Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery

Autor: Eva Kicková, Amir Sadeghi, Jooseppi Puranen, Shirin Tavakoli, Merve Sen, Veli-Pekka Ranta, Blanca Arango-Gonzalez, Sylvia Bolz, Marius Ueffing, Stefano Salmaso, Paolo Caliceti, Elisa Toropainen, Marika Ruponen, Arto Urtti

Publikováno v: Pharmaceutics, Vol 14, Iss 1, p 12 (2021)

The treatment of retinal diseases by intravitreal injections requires frequent administration unless drug delivery systems with long retention and controlled release are used. In this work, we focused on pullulan (≈67 kDa) conjugates of dexamethaso

Externí odkaz: https://doaj.org/article/612633861f1142a38420b60bad55386f

Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery

Autor: Eva Kicková, Amir Sadeghi, Jooseppi Puranen, Shirin Tavakoli, Merve Sen, Veli-Pekka Ranta, Blanca Arango-Gonzalez, Silvia Bolz, Marius Ueffing, Stefano Salmaso, Paolo Caliceti, Elisa Toropainen, Marika Ruponen, Arto Urtti

Publikováno v: Pharmaceutics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::51624e26664f38c56e3dfef01b62a010

Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery

Autor: Urtti, Eva Kicková, Amir Sadeghi, Jooseppi Puranen, Shirin Tavakoli, Merve Sen, Veli-Pekka Ranta, Blanca Arango-Gonzalez, Sylvia Bolz, Marius Ueffing, Stefano Salmaso, Paolo Caliceti, Elisa Toropainen, Marika Ruponen, Arto

Publikováno v: Pharmaceutics; Volume 14; Issue 1; Pages: 12

The treatment of retinal diseases by intravitreal injections requires frequent administration unless drug delivery systems with long retention and controlled release are used. In this work, we focused on pullulan (≈67 kDa) conjugates of dexamethaso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::162785c0a127d493c3b36dc2d05a1fb4

Retinal neuroprotection by controlled release of a VCP inhibitor from self-assembled nanoparticles

Autor: Paolo Caliceti, Merve Sen, Blanca Arango-Gonzalez, Jooseppi Puranen, Eva Kicková, Al-Amin, Amir Sadeghi, Arto Urtti, Stefano Salmaso, Marius Ueffing

Publikováno v: J Control Release

Mutations in rhodopsin lead to its misfolding resulting in autosomal dominant retinitis pigmentosa (adRP). Pharmacological inhibition of the ATP-driven chaperone valosin-containing protein (VCP), a molecular checkpoint for protein quality control, sl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d304fe058f673522e81030f4ae407d

Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery.

Autor: Kicková, Eva¹ (AUTHOR) eva.kickova@yahoo.com, Sadeghi, Amir² (AUTHOR) amir.sadeghi@uef.fi, Puranen, Jooseppi² (AUTHOR) jooseppi.puranen@uef.fi, Tavakoli, Shirin³ (AUTHOR) shirin.tavakoli@helsinki.fi, Sen, Merve⁴ (AUTHOR) merve.sen@uni-tuebingen.de, Ranta, Veli-Pekka² (AUTHOR) veli-pekka.ranta@uef.fi, Arango-Gonzalez, Blanca⁴ (AUTHOR) blanca.arango-gonzalez@klinikum.uni-tuebingen.de, Bolz, Sylvia⁴ (AUTHOR) sylvia.bolz@uni-tuebingen.de, Ueffing, Marius⁴ (AUTHOR) mue@klinikum.uni-tuebingen.de, Salmaso, Stefano¹ (AUTHOR) stefano.salmaso@unipd.it, Caliceti, Paolo¹ (AUTHOR) paolo.caliceti@unipd.it, Toropainen, Elisa² (AUTHOR) elisa.toropainen@uef.fi, Ruponen, Marika² (AUTHOR) marika.ruponen@uef.fi, Urtti, Arto^2,3,5 (AUTHOR) arto.urtti@uef.fi

Publikováno v: Pharmaceutics. Jan2022, Vol. 14 Issue 1, p12-12. 1p.