Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Eva Karamitopoulou"'
Autor:
Asma Ahmed, Cindy Reinhold, Eileen Breunig, Truong San Phan, Lea Dietrich, Feodora Kostadinova, Corinne Urwyler, Verena M. Merk, Mario Noti, Israel Toja da Silva, Konstantin Bode, Fatima Nahle, Anna Pia Plazzo, Julia Koerner, Regula Stuber, Constantin Menche, Eva Karamitopoulou, Henner F. Farin, Kenneth J. Gollob, Thomas Brunner
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1545-1566 (2023)
Control of tumour development and growth by the immune system critically defines patient fate and survival. What regulates the escape of colorectal tumours from destruction by the immune system remains currently unclear. Here, we investigated the rol
Externí odkaz:
https://doaj.org/article/e2887ae1833f4172bd9bbea51ee70193
Autor:
L. Paige Ferguson, Jovylyn Gatchalian, Matthew L. McDermott, Mari Nakamura, Kendall Chambers, Nirakar Rajbhandari, Nikki K. Lytle, Sara Brin Rosenthal, Michael Hamilton, Sonia Albini, Martin Wartenberg, Inti Zlobec, José A. Galván, Eva Karamitopoulou, Vera Vavinskaya, Alexis Wascher, Andrew M. Lowy, Christian M. Schürch, Pier Lorenzo Puri, Benoit G. Bruneau, Diana C. Hargreaves, Tannishtha Reya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Clinical management of pancreatic cancer remains challenging. Here, the authors suggest SMARCD3 as a potential epigenetic dependency establishing the metabolic landscape in aggressive pancreatic cancer cells and as a potential therapeutic target in p
Externí odkaz:
https://doaj.org/article/eadb3f5725a947ddb9882b3a7d976ccc
Autor:
Christiane Palm, Catherine E. Connolly, Regina Masser, Barbara Padberg Sgier, Eva Karamitopoulou, Quentin Simon, Beata Bode, Marianne Tinguely
Publikováno v:
Diagnostics, Vol 13, Iss 1, p 168 (2023)
The expression of human epidermal growth factor receptor 2 (HER2) protein or gene transcripts is critical for therapeutic decision making in breast cancer. We examined the performance of a digitalized and artificial intelligence (AI)-assisted workflo
Externí odkaz:
https://doaj.org/article/368f7b588e374b6382fda9a077729234
Autor:
Hassan Sadozai, Animesh Acharjee, Serenella Eppenberger-Castori, Beat Gloor, Thomas Gruber, Mirjam Schenk, Eva Karamitopoulou
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Background: The aggressive biology and treatment refractory nature of pancreatic ductal adenocarcinoma (PDAC) significantly limits long-term survival. Examining the tumor microenvironment (TME) of long-term survivors (LTS) of PDAC offers the potentia
Externí odkaz:
https://doaj.org/article/b5ae6b665e234a4cad33f6dbbcdd3069
Autor:
Eva Karamitopoulou
Publikováno v:
Cancers, Vol 14, Iss 6, p 1523 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is a biologically aggressive malignancy showing a remarkable resistance to existing therapies and is often diagnosed at an advanced stage, leaving only about 15–20% of patients with an option for surgical res
Externí odkaz:
https://doaj.org/article/f0e09e2ee51243b592d6340ea512b516
Autor:
Estefania Carrasco-Garcia, Lidia Lopez, Veronica Moncho-Amor, Fernando Carazo, Paula Aldaz, Manuel Collado, Donald Bell, Ayman Gaafar, Eva Karamitopoulou, Alexandar Tzankov, Manuel Hidalgo, Ángel Rubio, Manuel Serrano, Charles H. Lawrie, Robin Lovell-Badge, Ander Matheu
Publikováno v:
Cancers, Vol 14, Iss 4, p 916 (2022)
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers mainly due to spatial obstacles to complete resection, early metastasis and therapy resistance. The molecular events accompanying PDAC progression remain poorly und
Externí odkaz:
https://doaj.org/article/e8d1e6d226b6418f9784e565cc7bdb4d
Pancreatic Cancers with High Grade Tumor Budding Exhibit Hallmarks of Diminished Anti-Tumor Immunity
Publikováno v:
Cancers, Vol 13, Iss 5, p 1090 (2021)
Tumor budding is associated with epithelial-mesenchymal transition and diminished survival in a number of cancer types including pancreatic ductal adenocarcinoma (PDAC). In this study, we dissect the immune landscapes of patients with high grade vers
Externí odkaz:
https://doaj.org/article/79aafb3f517c4e8a8089bc2e906cc617
Autor:
Eva Karamitopoulou
Publikováno v:
Cancers, Vol 12, Iss 10, p 3076 (2020)
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis along with rising incidence rates and will be responsible for many cancer deaths in the future [...]
Externí odkaz:
https://doaj.org/article/742f0cfc11854ef4811608b1b23e565a
Autor:
Lukas Franz Mager, Viktor Hendrik Koelzer, Regula Stuber, Lester Thoo, Irene Keller, Ivonne Koeck, Maya Langenegger, Cedric Simillion, Simona P Pfister, Martin Faderl, Vera Genitsch, Irina Tcymbarevich, Pascal Juillerat, Xiaohong Li, Yu Xia, Eva Karamitopoulou, Ruth Lyck, Inti Zlobec, Siegfried Hapfelmeier, Rémy Bruggmann, Kathy D McCoy, Andrew J Macpherson, Christoph Müller, Bruce Beutler, Philippe Krebs
Publikováno v:
eLife, Vol 6 (2017)
Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease. Here, we reveal a critical role of the AS regulator epithelial splicing reg
Externí odkaz:
https://doaj.org/article/46127925fa504c6795248c15aa1ffdf6
Autor:
Giuseppe Sconocchia, Serenella Eppenberger-Castori, Inti Zlobec, Eva Karamitopoulou, Roberto Arriga, Andrea Coppola, Sara Caratelli, Giulio Cesare Spagnoli, Davide Lauro, Alessandro Lugli, Junyi Han#, Giandomenica Iezzi, Cristina Ferrone, Amedeo Ferlosio, Luigi Tornillo, Raoul Droeser, Piero Rossi, Antonio Attanasio, Soldano Ferrone, Luigi Terracciano
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 1, Pp 31-42 (2014)
The goal of this study was to determine the frequency of HLA class II antigen expression in colorectal carcinoma (CRC) tumors, its association with the clinical course of the disease, and the underlying mechanism(s). Two tissue microarrays constructe
Externí odkaz:
https://doaj.org/article/b1b1b96da2874fa2a0833dfda078018f