Výsledky vyhledávání

Antigen Specific T-Cell Responses Against Tumor Antigens are Controlled by Regulatory T Cells in Patients With Prostate Cancer

Autor: Markus Hohenfellner, Eva Huter, Yingzi Ge, Boris Hadaschik, Yun Su, Philipp Beckhove

Publikováno v: Journal of Urology. 187:1458-1465

Immunotherapy is a promising approach in an effort to control castration resistant prostate cancer. We characterized tumor antigen reactive T cells in patients with prostate cancer and analyzed the suppression of antitumor responses by regulatory T c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ea9c2f9b31e2c07f2e9eef2bd0da4f
https://doi.org/10.1016/j.juro.2011.11.083

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Engagement of TLR2 Does not Reverse the Suppressor Function of Mouse Regulatory T Cells, but Promotes Their Survival

Autor: Todd S. Davidson, Ethan M. Shevach, Eva Huter, Qian Chen

Publikováno v: The Journal of Immunology. 183:4458-4466

TLRs are a class of conserved pattern recognition receptors that are used by cells of the innate immune system. Recent studies have demonstrated the expression of TLRs on both human and mouse T cells raising the possibility that TLRs play a direct ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3d51962ce4a3e2b6f507c3968c3067a
https://doi.org/10.4049/jimmunol.0901465

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Induction of strong and persistent MelanA/MART-1-specific immune responses by adjuvant dendritic cell-based vaccination of stage II melanoma patients

Autor: Jürgen Knop, Helmut Jonuleit, Andrea Tuettenberg, Eva Huter, Alexander Enk, Christian Becker

Publikováno v: 27. Deutscher Krebskongress; 20060322-20060326; Berlin; DOCPO612 /20060320/

A significant percentage of stage II melanoma patients (tumor thickness >1 mm) remain at risk of tumor recurrence after primary tumor excision. In this study, we used tumor antigen-pulsed dendritic cells as an adjuvant for immunization of these “hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11f3d248c14aea2ec47d3dfbc1acac0
https://doi.org/10.1002/ijc.21679

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17. Mainzer Allergie-Workshop

Autor: Thomas Werfel, A. Cistero-Bahima, Alexander Gerbaulet, Sabine Ohlemacher, Bernadette Eberlein-König, Detlef Zillikens, Sonja Bailey, Mette Ribel, S. Soost, A. Güttsches, Hansjörg Schild, K. Heeg, Wolf-Georg Forssmann, Gabriele Weimer, C. Freising, R. Ludwig, Helmut Jonuleit, Stefanie Sommer, Yasemin Darcan, Robert Sabat, Jürgen Knop, Armin Braun, Ulf Forssmann, Tilo Biedermann, K. Ghoreschi, M. O’Keeffe, Shelley J Allen, Thilo Jakob, Stephan Sudowe, S. Ewig, Christian Kutzleb, Delphine C. Malherbe, G. Roider, Claudia Traidl-Hoffmann, Dave Dawbarn, Mar San-Miguel Moncin, Christoph Hüls, G. Burow, A.-K. Illner, M. Wittmann, Edgar Serfling, C. Bilitewski, Henning Weigt, M. Huhn, J. Kressel, D. Ernst, Kenny Pollock, Jürgen Grabbe, Stefanie Foerster, S. Glaser, T. Brüning, Franziska Ruëff, Â. Gaspar, Claudia Borelli, Carolyn Bauer, G. Pires, Eva Huter, M. Neumaier, Norbert Krug, Hanspeter Mart, Joachim Saloga, Valeska Heib, Eva Zahradnik, Jörg Kleine-Tebbe, Uta Jappe, S. Mkhlof, A. Conti, Lilla Landeck, Comelia Blume, S. Barth, S. Bade, Veit J. Erpenbeck, V. van Kampen, Eva Zindler, D. Wicklein, Arnd Petersen, Alexander Enk, Ulrike Seitzer, Tibor Veres, P. Rozynek, Stephan Baldus, Stefanie Förster, I. Dorn, Tobias Bopp, M. Meurer, Jan Kubach, U. Herz, Dagmar Simon, Helmut Renz, Franz-Josef Schneider, S. Werner, F. Haamann, M. Stöcker, Thomas Herzinger, M. Vetter, Torsten Zuberbier, Angelika B. Reske-Kunz, Günther Lametschwandtner, Guido Heine, M. Klotz, U. Zähringer, B. Backhaus, B. Summer, A. Boldt, W. Weber, Samuel B. Lehrer, Alex Straumann, Pius Heer, Stefan Vieths, Frank Siebenhaar, Peter Thomas, Tilmann Oppel, Eva Scharrer, Bernhard Przybilla, Torsten Schäfer, Shipra Gupta, Esra Tas, Lasse R. Braathen, K. Simon, Sebastian Straube, Karin Hartmann, T. Klockenbring, Andreas Wollenberg, Hae-Hyuk Lee, C. Hartz, G. Rohde, M. Schmelz, Milena Milovanovic, Margitta Worm, H. Hochrein, Jo Rae Wright, Ingrid Sander, W. A. Nockher, Christoph Schwärzler, K. Reinitz-Rademacher, Christina Nassenstein, Monika Raulf-Heimsoth, Albrecht Bufe, M. Schindewolf, S. Sel, C. Rundfeldt, Edgar Schmitt, Ingo Böttcher, Olga Weikum, Christoph Richter, Jan Gutermuth, P. Ahmad-Nejad, Iris Bellinghausen, Christian Müller, Tanja Stünkel, I. Weichenmeier, Katharina Albert, F. Alessandrini, S. Maier, Matthias Klein, Christina Hartmann, P. Rieber, P C Konturek, Rolf Merget, F. Eberhardt, Claudia Günther, Petra Weingarten, C. Hahn, K. Breuer, Evelyn Montermann, U.-C. Hipler, S. Schmelz, Wolf-Meinhard Becker, Julia Viebranz, B. Belloni, A. Nabe, Martin Raithel, R. Kaufmann, Jeroen Buters, S. Abraham, Hans-Peter Rihs, Claudia M. Trujillo-Vargas, Christian Becker, Rahul Purwar, D. Hartwig, Jens M. Hohlfeld, Jürgen Galle, Jörn Elsner, S. Klaus, Stephan Scheurer, S. Lubitz, Oliver Drews, Eckhart G. Hahn, Klaus J. Erb, E. P. Rieber, Wolfgang Schober, C. Betzel, S. Mrabet-Dahbi, Bernhard F. Gibbs, S. Wildner, W. H. Boehncke, A. Ebling, B. Schuhmann, Ralf Bälder, Bettina König, Stefanie Randow, Sandra Schulz-Maronde, Ulf Darsow, Martin Blüggel, M. M. San Miguel-Moncin, Martina Thiel, S. Kespohl, Andreas J. Bircher, Ursula Krämer, Petra Lutter, E. Lindhoff-Last, M. Wegmann, Michael Stassen, Heidrun Behrendt, Aleksandra Heitland, Hans-Uwe Simon, Franziska Ruäff, A. Kasche, K. Gehlhar, Liane M. Preussner, Kilian Eyerich, Jabbar Ahmed, Johannes Huss-Marp, Katja Langer, Stefan Klein-Heßling, Peter Elsner, Alexander Kapp, M. Hoffmann, Michael Weidenhiller, Markus Magerl, Steffen Schmitt, B. Schlatter, Knut Schäkel, Dietmar A. Herold, Barbara Fuchs, C. Fleischer, Marcus Maurer, S.E. Escher, Gerald Reese, Andrea Bauer, S. Löseke, E.-M. Fiedler, Antal Rot, H.-H. Gorris, Angelika Görg, José M. Carballido, Alois Palmetshofer, Knut Brockow, M. Braun-Falco, Iris Lauer, Johannes Ring, Karl Sotlar, Tina Ristau, K. Hirsch, S. Riecken, R. Draheim, A. Pirayesh, M. Heitmann, Kirsten Tangemann

Publikováno v: Allergo Journal. 14:30-47

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08d81aafb53f887ada4cf01a1f758c7c
https://doi.org/10.1007/bf03370389

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Single Base Mutation in the Fumarate Hydratase Gene Leading to Segmental Cutaneous Leiomyomatosis

Autor: Alexander Enk, Eva Huter, Uta Jappe, Wolfgang Hartschuh, Noel C. Wortham

Publikováno v: Acta Dermato-Venereologica. 88:63-65

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a38c57b73ea766c2a8b387f04c27be3
https://doi.org/10.2340/00015555-0341

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The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells

Autor: Julia Horn, Richard A. Kroczek, Sabine Stoll, Eva Huter, Bodo Grimbacher, Mario Hubo, Jürgen Knop, Helmut Jonuleit, Andrea Tuettenberg

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 182(6)

Tolerogenic dendritic cells (DC) play an important role in maintaining peripheral T cell tolerance in steady-state conditions through induction of anergic, IL-10-producing T cells with suppressive properties. ICOS, an activation-induced member of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66905caba35a1113546858d585694ef6
https://pubmed.ncbi.nlm.nih.gov/19265111

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Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function

Autor: Jürgen Knop, John Wijdenes, Petra Lutter, Christian Becker, Tobias Bopp, Sabine Stoll, Eva Huter, Christoph Richter, Hansjörg Schild, Jan Kubach, Petra Weingarten, Stefan Müllner, Tobias Warger, Edgar Schmitt, Helmut Jonuleit

Publikováno v: Blood. 110(5)

CD4+CD25+Foxp3+ regulatory T cells (CD25+ Treg cells) direct the maintenance of immunological self-tolerance by active suppression of autoaggressive T-cell populations. However, the molecules mediating the anergic state and regulatory function of CD2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a134c920ddafdd5b0310f77236bb310a
https://pubmed.ncbi.nlm.nih.gov/17502455

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Dendritic cells: sentinels of immunity and tolerance

Autor: Eva Huter, Jan Kubach, Helmut Jonuleit, Christian Becker, Edgar Schmitt, Andrea Tuettenberg, Kerstin Steinbrink

Publikováno v: International journal of hematology. 81(3)

The induction of effective antigen-specific T-cell immunity to pathogens without the initiation of autoimmunity has evolved as a sophisticated and highly balanced immunoregulatory mechanism. This mechanism assures the generation of antigen-specific e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75936c52d66d8a5fc85fbf3aebafd6bb
https://pubmed.ncbi.nlm.nih.gov/15814330

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Spontaneous Regression and Recurrence in a Case of Nodular Fasciitis

Autor: Mark C Udey, Richard M. Sherry, Eva Huter, Chyi-Chia Richard Lee

Publikováno v: Acta Dermato Venereologica. 89:438-439

Nodular fasciitis is a sporadic tumor that results from a benign proliferation of myofibroblasts in soft tissues. It presents clinically as a rapidly-growing firm nodule, most often localized in the subcutaneous tissue (1). While it may arise in any

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a6959c8f57ccd4073b0ddb40413e835
https://doi.org/10.2340/00015555-0664

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