Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Eva Hrubá"'
1
Akademický článek
Metastasising ameloblastoma or ameloblastic carcinoma? A case report with mutation analyses
Autor: Pavel Hurník, Barbora Moldovan Putnová, Tereza Ševčíková, Eva Hrubá, Iveta Putnová, Josef Škarda, Martin Havel, Oldřich Res, Jakub Cvek, Marcela Buchtová, Jan Štembírek
Publikováno v: BMC Oral Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Ameloblastic carcinoma and metastasising ameloblastoma are rare epithelial odontogenic tumours with aggressive features. Distinguishing between these two lesions is often clinically difficult but necessary to predict tumour behavi
Externí odkaz: https://doaj.org/article/673c883fc97c4c0bbeba890c7662d8f9
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2
Akademický článek
Epigenetic Regulations of Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Autor: Pavel Hurník, Zuzana Chyra, Tereza Ševčíková, Jan Štembírek, Kateřina Smešný Trtková, Daria A. Gaykalova, Marcela Buchtová, Eva Hrubá
Publikováno v: Frontiers in Genetics, Vol 13 (2022)
Carcinomas of the oral cavity and oropharynx belong among the ten most common malignancies in the human population. The prognosis of head and neck squamous cell carcinoma (HNSCC) is determined by the degree of invasiveness of the primary tumor and by
Externí odkaz: https://doaj.org/article/7c08e8d0d1a54f2892d0a45881e22b4e
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3
Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling
Autor: Tomáš Zikmund, Miroslav Varecha, Maria Hovorakova, Michaela Kavkova, Pavel Krejci, Linda Dalecka, Marcela Buchtová, Jozef Kaiser, Eva Hrubá, Miloš Macholán, Michaela Bosakova
Publikováno v: Journal of Bone and Mineral Research. 36:2258-2274
The Sprouty family is a highly conserved group of intracellular modulators of receptor tyrosine kinase (RTK)-signaling pathways, which have been recently linked to primary cilia. Disruptions in the structure and function of primary cilia cause inheri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1201f537862320187e827407fc38c275
https://doi.org/10.1002/jbmr.4427
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4
Adherence to Oral Nutritional Supplements After Being Discharged from the Hospital is Low but Improves Outcome in Patients with Advanced Chronic Liver Disease
Autor: Pavol Molcan, Jana Vnencakova, Beata Skvarkova, Lukáš Lafférs, Eva Hrubá, Tomas Koller, Lubomir Skladany
Publikováno v: Patient preference and adherence
Lubomir Skladany,1 Jana Vnencakova,1 Lukas Laffers,2 Beata Skvarkova,1 Eva Hrubá,1 Pavol Molcan,1 Tomas Koller3 1Hepatology, Gastroenterology and Transplantation (HEGITO) Department of the 2nd Department of Medicine, Slovak Medical University, FD Ro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7cf0a7ced39ca0b6c24ac0673c004c
http://europepmc.org/articles/PMC7802017
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5
Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling
Autor: Marcela Buchtová, Jiri Kohoutek, Ganesh V. Pusapati, Katerina Svozilova, Isabelle Thiffault, Ivan Duran, Lukas Balek, Pavel Krejci, Sara P. Abraham, Michael J. Bamshad, Daniel H. Cohn, Deborah Krakow, Michaela Bosakova, S. Paige Taylor, Tomáš Bárta, Deborah A. Nickerson, Vitezslav Bryja, Tomasz Witold Radaszkiewicz, Eva Hrubá, Eric T. Rush, Miroslav Varecha, Alexandru Nita, Rajat Rohatgi, Jorge H. Martin
Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
Mutations in genes affecting primary cilia cause ciliopathies, a diverse group of disorders often affecting skeletal development. This includes Jeune syndrome or asphyxiating thoracic dystrophy (ATD), an autosomal recessive skeletal disorder. Unravel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208e6515d54d4288226d733a8d34fa33
https://pubmed.ncbi.nlm.nih.gov/33200460
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7
In Vitro Transformation of Human Bronchial Epithelial Cells by Diesel Exhaust Particles: Gene Expression Profiling and Early Toxic Responses
Autor: Miroslav Machala, Jan Topinka, Eva Hrubá, Aage Haugen, Kristine B. Gutzkow, Kristyna Vrbova, Yke Jildouw Arnoldussen, Anani K.J. Afanou, Helena Libalova, Steen Mollerup, Øivind Skare, Pavel Rossner, Iselin Rynning, Jørn A. Holme, Jiri Neca
Publikováno v: Toxicological Sciences
Occupational exposure to diesel exhaust may cause lung cancer in humans. Mechanisms include DNA-damage and inflammatory responses. Here, the potential of NIST SRM2975 diesel exhaust particles (DEP) to transform human bronchial epithelial cells (HBEC3
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7eda172dbc79d1d8878f7bb6abdcaf
https://doi.org/10.1093/toxsci/kfy183
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8
Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro
Autor: Kateřina Pěnčíková, Petra Brenerová, Eva Hrubá, Lenka Pálková, Lucie Svržková, Jan Vondráček, Hans-Joachim Lehmler, Miroslav Machala
Publikováno v: Environmental science and pollution research international. 25(17)
PCB 136 is an environmentally relevant chiral PCB congener, which has been found in vivo to be present in form of rotational isomers (atropisomers). Its atropselective biotransformation or neurotoxic effects linked with sensitization of ryanodine rec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e559b22c95184855489affe4830c29
https://pubmed.ncbi.nlm.nih.gov/29124635
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