Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eva Hoi Ching Tang"'
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Prostaglandin E2 (PGE2) is an endogenous lipid mediator, produced from the metabolism of arachidonic acids, upon the sequential actions of phospholipase A2, cyclooxygenases, and prostaglandin E synthases. The various biological functions governed by
Externí odkaz:
https://doaj.org/article/cd8bccebb52642bdb3a1054af24a3a5d
Autor:
Eva Hoi Ching Tang, Ishan Lakhani, Zhengyuan Xia, Hao Liu, Fan Ying, Ningning Liu, Shiming Liu
Publikováno v:
Biochemical and Biophysical Research Communications. 548:196-203
Background Cardiac fatty acid metabolism is essential for maintaining normal cardiac function at baseline and in response to various disease stress, like diabetes. EP4 is widely expressed in cardiomyocytes and has been demonstrated to play a role in
Autor:
Fan Ying, Xin Yi Chen, Aimin Xu, Eva Hoi Ching Tang, Paul M. Vanhoutte, Yin Cai, Hoi Kin Wong
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO3-6
Publikováno v:
The FASEB Journal. 31:4023-4036
The purpose of this study was to investigate whether genetic ablation of prostaglandin E receptor subtype 4 (EP4) affects white adipose tissue (WAT) remodeling mediated by β3-adrenergic stimulation...
Autor:
Zhengyuan Xia, Eva Hoi Ching Tang, Erfei Song, Dengwen Zhang, Fan Ying, Michael G. Irwin, Lin Wang, Yin Cai, Hao Liu, Liang Ge
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(3)
Ischemic heart disease is a leading cause of morbidity and mortality. Repressor activator protein 1 (Rap1), an established telomere-associated protein, is a novel modulator of hypoxia-induced apoptosis. This study aimed to explore the potential direc
Publikováno v:
Acta Physiologica. 219:22-96
The endothelium can evoke relaxations of the underlying vascular smooth muscle, by releasing vasodilator substances. The best-characterized endothelium-derived relaxing factor (EDRF) is nitric oxide (NO) which activates soluble guanylyl cyclase in th
Publikováno v:
The FASEB Journal. 32
Publikováno v:
The FASEB Journal. 29:4924-4936
Upon high-fat feeding, prostaglandin E receptor subtype 4 (EP4)-knockout mice gain less body weight than their EP4(+/+) littermates. We investigated the cause of the lean phenotype. The mice showed a 68.8% reduction in weight gain with diminished fat
Autor:
Koichi Shimizu, Ge Xuan, Chi Kin Wong, Paul M. Vanhoutte, Peter Libby, Yin Cai, Galina K. Sukhova, Viviane Z. Rocha, Eva Hoi Ching Tang, Aimin Xu
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 358-368 (2015)
Inflammation of adipose tissue induces metabolic derangements associated with obesity. Thus, determining ways to control or inhibit inflammation in adipose tissue is of clinical interest. The present study tested the hypothesis that in mouse adipose
Autor:
Ianto Bosheng Huang, Xin Yi Chen, Paul M. Vanhoutte, Zhengyuan Xia, Yin Cai, Fan Ying, Eva Hoi Ching Tang, Hoi Kin Wong, Aimin Xu
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1863(9)
Prostaglandin E receptor subtype 4 (EP4) knockout mice develops spontaneous hypercholesterolemia but the detailed mechanisms by which EP4 affects cholesterol homeostasis remains unexplored. We sought to determine the cause of hypercholesterolemia in