Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Eva Guijarro Perez"'
Autor:
Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
RNF5 is a ubiquitin ligase regulating ER stress response. Here the authors show that Rnf5 deficiency potentiates immune response against melanoma via altered microbiota, and isolate bacterial strains that confer the same phenotype to wild type mice.
Externí odkaz:
https://doaj.org/article/47e63127b17f4776963dab1e5a8faa8f
Autor:
Lisa Elmén, Dennie T. Frederick, Yibo Xian, Bas J. G. Baaten, Yan Li, Amir Orian, Hyungsoo Kim, Robert Schmaltz, Kevin M. Brown, Glenn Merlino, Roberto Tinoco, Eytan Ruppin, Ali Khateb, Ilanit Boyango, Avinash Das Sahu, Eva Guijarro Perez, Yongmei Feng, Randal J. Kaufman, Chi-Ping Day, Ze'ev Ronai, Tao Long, Lihi Tzur, Gil Bar-Sela, Emily Avitan-Hersh, Marcus Bosenberg, Shiri K. Ashkenazi, Mitchell P. Levesque, Shoshana Roizman, Linda M. Bradley, Raphy Zarecki, Yu Fujita, Scott N. Peterson, Colin R. Goding, Kerrie L. Marie, Reinhard Dummer, Rafael S. Segura Muñoz, Shibu Yooseph, Keith T. Flaherty, Tongwu Zhang, Amanda E. Ramer-Tait, Igor Segota, Miguel A. Tam
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Li, Y, Tinoco, R, Elmén, L, Segota, I, Xian, Y, Fujita, Y, Sahu, A, Zarecki, R, Marie, K L, Feng, Y, Khateb, A, Frederick, D T, Ashkenazi, S K, Kim, H, Pérez-Guijarro, E, Day, C-P, Segura Muñoz, R S, Schmaltz, R, Yooseph, S, Tam, M A, Zhang, T, Avitan-Hersh, E, Tzur, L, Roizman, S, Boyango, I, Bar-Sela, G, Orian, A, Kaufman, R J, Bosenberg, M, Goding, C R, Baaten, B, Levesque, M P, Dummer, R, Brown, K M, Merlino, G, Ruppin, E, Flaherty, K T, Ramer-Tait, A, Long, T, Peterson, S N, Bradley, L M & Ronai, Z A 2019, ' Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice ', Nature Communications, vol. 10, 1492, pp. 1-16 . https://doi.org/10.1038/s41467-019-09525-y
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Li, Y, Tinoco, R, Elmén, L, Segota, I, Xian, Y, Fujita, Y, Sahu, A, Zarecki, R, Marie, K L, Feng, Y, Khateb, A, Frederick, D T, Ashkenazi, S K, Kim, H, Pérez-Guijarro, E, Day, C-P, Segura Muñoz, R S, Schmaltz, R, Yooseph, S, Tam, M A, Zhang, T, Avitan-Hersh, E, Tzur, L, Roizman, S, Boyango, I, Bar-Sela, G, Orian, A, Kaufman, R J, Bosenberg, M, Goding, C R, Baaten, B, Levesque, M P, Dummer, R, Brown, K M, Merlino, G, Ruppin, E, Flaherty, K T, Ramer-Tait, A, Long, T, Peterson, S N, Bradley, L M & Ronai, Z A 2019, ' Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice ', Nature Communications, vol. 10, 1492, pp. 1-16 . https://doi.org/10.1038/s41467-019-09525-y
Nature Communications
Accumulating evidence points to an important role for the gut microbiome in anti-tumor immunity. Here, we show that altered intestinal microbiota contributes to anti-tumor immunity, limiting tumor expansion. Mice lacking the ubiquitin ligase RNF5 exh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034278988dcad7bc3424498560983469
https://doi.org/10.1038/s41467-019-09525-y
https://doi.org/10.1038/s41467-019-09525-y