Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Eva Grosse Berkhoff"'
Autor:
Mike W Helms, Walter Stöcker, Gertrud Brachtendorf, Eva Grosse Berkhoff, Frank Wegmann, Oliver Schilling, Irene Yiallouros, Jasna Peter-Katalinić, Astrid Auge, Simone König, Hans Jürgen Hinz, Bernd Beermann, Reinhild Kappelhoff
Astacin (EC 3.4.24.21) is a prototype for the astacin family and for the metzincin superfamily of zinc peptidases, which comprise membrane-bound and secreted enzymes involved in extracellular proteolysis during tissue development and remodelling. Gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd875a3c701d9b7e7d3d8dd2ccc0f11f
https://doi.org/10.1016/s0022-2836(02)01102-6
https://doi.org/10.1016/s0022-2836(02)01102-6
Autor:
Walter Stöcker, Markus Höwel, Vera Hintze, Carsten Wermter, Irene Yiallouros, Eva Grosse Berkhoff, Bernd Beermann, Christoph Becker-Pauly
Publikováno v:
Biochemistry. 45(21)
The procollagen C-proteinase (PCP) is a zinc peptidase of the astacin family and the metzincin superfamily. The enzyme removes the C-terminal propeptides of fibrillar procollagens and activates other matrix proteins. Besides its catalytic protease do
Publikováno v:
FEBS Letters. (3):224-228
The catalytic zinc of astacin, a prototype of the astacin family and the metzincin superfamily of metalloproteinases is coordinated by three histidines, a glutamate bound water and a tyrosine. In order to assess the roles of active site key residues,