Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eva Geuss"'
Autor:
Typhaine Anquetil, Marie-Pierre Gratacap, Gaëtan Chicanne, Christoph Kleinschnitz, Eva Geuss, Vincent Larrue, Jean Darcourt, Julien Viaud, Karim Hnia, Aude Jaffre, Denis Vivien, Bernard Payrastre, Cyrille Orset, Romain Solinhac, Bart Vanhaesebroeck
Publikováno v:
EMBO Rep
Endothelium protection is critical, because of the impact of vascular leakage and edema on pathological conditions such as brain ischemia. Whereas deficiency of class II phosphoinositide 3‐kinase alpha (PI3KC2α) results in an increase in vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4958548fa9eb8e8f063adeb207098171
https://doi.org/10.15252/embr.202051299
https://doi.org/10.15252/embr.202051299
Autor:
Katja Aurbach, Sascha Geue, Christoph Kleinschnitz, Harald Schulze, Britta Walker-Allgaier, Oliver Borst, Daniela Semeniak, Madhumita Chatterjee, Irina Pleines, Melanie Märklin, Thierry Buchou, Eva Geuss, Meinrad Gawaz, David Stegner, Patrick Münzer, Helmut R. Salih, David W. Litchfield, Friederike Langhauser, Irene Gonzalez Menendez, Florian Lang, Bernhard Nieswandt, Leticia Quintanilla-Martinez
Publikováno v:
Blood. 130:2774-2785
Platelets, anucleated megakaryocyte (MK)-derived cells, play a major role in hemostasis and arterial thrombosis. Although protein kinase casein kinase 2 (CK2) is readily detected in MKs and platelets, the impact of CK2-dependent signaling on MK/plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dc20cd1d476e7340cfacac240a01dc2
https://doi.org/10.1182/blood-2017-05-784413
https://doi.org/10.1182/blood-2017-05-784413
Publikováno v:
Experimental Neurology, 288, 94-103. Elsevier Science
Treatment of neuropathic pain remains challenging as the etiology is heterogeneous and pathomechanisms are incompletely understood. One possible mechanism is oxidative stress due to unphysiological reactive oxygen species (ROS) formation. The only kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8f5e0af61a6533357dd440c40e332a
https://doi.org/10.1016/j.expneurol.2016.11.008
https://doi.org/10.1016/j.expneurol.2016.11.008
Autor:
Christoph Kleinschnitz, Josua Guthmann, Michael K. Schuhmann, Janine Gronewold, Dirk M. Hermann, Guido Stoll, Peter Kraft, Eva Geuss, Anne-Carina Scharf, Michael Bieber, Friederike Langhauser, Stine Mencl, Thorsten R. Doeppner, Sarah C. Hopp, Jonas Leinweber
Publikováno v:
Stroke. 50(10)
Background and Purpose— The selection of appropriate neurological scores and tests is crucial for the evaluation of stroke consequences. The validity and reliability of neurological deficit scores and tests has repeatedly been questioned in ischemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ac2e9c7f317a2f1aa924036479c7d1
https://pubmed.ncbi.nlm.nih.gov/31412755
https://pubmed.ncbi.nlm.nih.gov/31412755
Autor:
Valerie Gailus-Durner, Eva Geuss, Manuela G. López, Christoph Kleinschnitz, Dirk H. Busch, Martin Hrabé de Angelis, Pamela W. M. Kleikers, Ana I. Casas, Harald H.H.W. Schmidt, Thure Adler, Friederike Langhauser, Javier Egea
Publikováno v:
Journal of Clinical Investigation, 129(4), 1772-1778. American Society for Clinical Investigation
Journal of Clinical Investigation
J. Clin. Invest. 129, 1772-1778 (2019)
Journal of Clinical Investigation
J. Clin. Invest. 129, 1772-1778 (2019)
Ischemic stroke is a predominant cause of disability worldwide, with thrombolytic or mechanical removal of the occlusion being the only therapeutic option. Reperfusion bears the risk of an acute deleterious calcium-dependent breakdown of the blood-br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e1ff7a57eacd128f9a7b45a3869851
https://cris.maastrichtuniversity.nl/en/publications/8f6e9b7d-9ac2-4c15-b203-351e73cdd4c8
https://cris.maastrichtuniversity.nl/en/publications/8f6e9b7d-9ac2-4c15-b203-351e73cdd4c8
Autor:
Catharina C. Gross, Linda Groeneweg, Venu Narayanan, Tilman Schneider-Hohendorf, Christoph Kleinschnitz, Alexander M. Herrmann, Sven G. Meuth, Susann Eichler, Beate E. Kehrel, Heinz Wiendl, Monika Merker, Lisa Schüngel, Chloi-Magdalini Asaridou, Eva Geuß, Tobias Ruck, Kerstin Göbel
Blood–brain barrier (BBB) disruption and transendothelial trafficking of immune cells into the central nervous system (CNS) are pathophysiological hallmarks of neuroinflammatory disorders like multiple sclerosis (MS). Recent evidence suggests that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2181b0feff36d4f1f0d135ec07139100
https://www.ncbi.nlm.nih.gov/pubmed/30559188
https://www.ncbi.nlm.nih.gov/pubmed/30559188
Autor:
Elizabeth J. Haining, Eva Geuss, Christoph Kleinschnitz, Ayesha A. Baig, David Stegner, Bernhard Nieswandt, Attila Braun, Podchanart Wanitchakool, Sarah Beck, Johan W. M. Heemskerk, Karl Kunzelmann, Frauke Swieringa, Michael K. Schuhmann
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 36(11), 2152-2157. LIPPINCOTT WILLIAMS & WILKINS
Objective— It is known that both platelets and coagulation strongly influence infarct progression after ischemic stroke, but the mechanisms and their interplay are unknown. Our aim was to assess the contribution of the procoagulant platelet surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc53be583f3f251689677476524da425
https://doi.org/10.1161/atvbaha.116.307727
https://doi.org/10.1161/atvbaha.116.307727
Autor:
Florian Lang, Daniela Eißler, Martin Schaller, Gregor Hron, Eva Geuss, Dominik Rath, Christoph Kleinschnitz, Tobias Geisler, Elke Schaeffeler, Sascha Geue, Stefan Winter, Matthias Schwab, Oliver Borst, Andreas Greinacher, Meinrad Gawaz, Patrick Münzer, Monika Meinert, Britta Walker-Allgaier
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36:1507-1516
Objective— Activation of platelets by subendothelial collagen results in an increase of cytosolic Ca 2+ concentration ([Ca 2+ ] i ) and is followed by platelet activation and thrombus formation that may lead to vascular occlusion. The present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3746cd88c046e7993ea6939b80d46d07
https://doi.org/10.1161/atvbaha.115.307105
https://doi.org/10.1161/atvbaha.115.307105
Autor:
Pamela W. M. Kleikers, Jörg Menche, Manuela G. López, Friederike Langhauser, Christoph Kleinschnitz, Ana I. Casas, Vu-Thao-Vi Dao, Harald H.H.W. Schmidt, Eva Geuss, Albert-L Barabási, Emre Guney
Publikováno v:
NPJ Systems Biology and Applications
npj Systems Biology and Applications, Vol 4, Iss 1, Pp 1-13 (2018)
NPJ systems biology and applications, 4:8. Nature Publishing Group
npj Systems Biology and Applications, Vol 4, Iss 1, Pp 1-13 (2018)
NPJ systems biology and applications, 4:8. Nature Publishing Group
Network medicine utilizes common genetic origins, markers and co-morbidities to uncover mechanistic links between diseases. These links can be summarized in the diseasome, a comprehensive network of disease–disease relationships and clusters. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a911853aeaf50da6ed8b412a44b2b3
http://europepmc.org/articles/PMC5799370
http://europepmc.org/articles/PMC5799370
Autor:
Patrick, Münzer, Britta, Walker-Allgaier, Sascha, Geue, Friederike, Langhauser, Eva, Geuss, David, Stegner, Katja, Aurbach, Daniela, Semeniak, Madhumita, Chatterjee, Irene, Gonzalez Menendez, Melanie, Märklin, Leticia, Quintanilla-Martinez, Helmut R, Salih, David W, Litchfield, Thierry, Buchou, Christoph, Kleinschnitz, Florian, Lang, Bernhard, Nieswandt, Irina, Pleines, Harald, Schulze, Meinrad, Gawaz, Oliver, Borst
Publikováno v:
Blood. 130(25)
Platelets, anucleated megakaryocyte (MK)-derived cells, play a major role in hemostasis and arterial thrombosis. Although protein kinase casein kinase 2 (CK2) is readily detected in MKs and platelets, the impact of CK2-dependent signaling on MK/plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9eaeca9c49cb16d3ca9c70e96a165755
https://pubmed.ncbi.nlm.nih.gov/29269531
https://pubmed.ncbi.nlm.nih.gov/29269531