Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Eva Figueroa"'
Publikováno v:
Con A de Animación, Iss 5, Pp 78-87 (2015)
El Asombroso Mundo de Gumball (The Amazing World of Gumball, Ben Bocquelet, Mic Graves), es una serie que, desde su comienzo en 2011, se ha ganado un hueco especial en la parrilla de Cartoon Network, siendo, junto con Hora de aventuras (Adventure Tim
Externí odkaz:
https://doaj.org/article/7e2f96a48fcf46a48e798568d973c5d7
Autor:
Noelia Eva Figueroa
Publikováno v:
Revista Filosofía UIS, Vol 14, Iss 2 (2015)
Este articulo aborda, desde los escritos de Walter Benjamin, la peculiar forma del autor de pensar la intervencion politica practica desde el lugar de los intelectuales. Para esto, hemos elegido debatir sobre algunas de las figuras del heroe en la mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f96c6ab6ce57c33ca94d2efa06928e
https://revistas.uis.edu.co/index.php/revistafilosofiauis/article/view/5706
https://revistas.uis.edu.co/index.php/revistafilosofiauis/article/view/5706
Autor:
David M. Cross, Glyn Williams, Steven Howard, Julia E. Matthews, Marc O'Reilly, Mladen Vinkovic, Paul Graham Wyatt, Adrian Liam Gill, Lindsay A. Devine, John A. Boulstridge, Jayne Curry, Lynsey Fazal, Michelle Heathcote, Rachel McMenamin, Eva Figueroa Navarro, Valerio Berdini, Michael Alistair O'brien, Sarita Maman, Maria Grazia Carr, Theresa Rachel Early, Dominic Tisi, Matthias Reule, David C. Rees
Publikováno v:
Journal of Medicinal Chemistry. 52:379-388
Here, we describe the identification of a clinical candidate via structure-based optimization of a ligand efficient pyrazole-benzimidazole fragment. Aurora kinases play a key role in the regulation of mitosis and in recent years have become attractiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da04922729ad83e0f7fa4188e4f45b3
https://doi.org/10.1021/jm800984v
https://doi.org/10.1021/jm800984v
Autor:
John A. Boulstridge, Theresa Rachel Early, Gordon Saxty, Rachel McMenamin, Matthias Reule, David M. Cross, Lindsay A. Devine, Gary Trewartha, Michael Alistair O'brien, E. Jonathan Lewis, Paul Graham Wyatt, Eva Figueroa Navarro, M. Squires, Margaret T. Walker, Alison Jo-Anne Woolford, Lisa C A Seavers, Valerio Berdini, Marc O'Reilly, Maria Grazia Carr, Andrew James Woodhead, Donna-Michelle Smith, Deborah J. Davis, Ruth Feltell
Publikováno v:
Journal of Medicinal Chemistry. 51:4986-4999
The application of fragment-based screening techniques to cyclin dependent kinase 2 (CDK2) identified multiple (>30) efficient, synthetically tractable small molecule hits for further optimization. Structure-based design approaches led to the identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8871c4117346be79e808d8fa39ce199e
https://doi.org/10.1021/jm800382h
https://doi.org/10.1021/jm800382h
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
Con A de Animación, Iss 5, Pp 78-87 (2015)
instname
Con A de Animación, Iss 5, Pp 78-87 (2015)
[EN] Ben Bocquelet’s & Mic Graves’ The Amazing world of Gumball is a TV series that since 2011 has earned a special position in the programming of Cartoon Network. Along with Pendleton Ward’s Adventure Time (2010-) and J.G. Quintel’s Regular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733f6928fcc8d5891de104963c0b262d
https://doi.org/10.4995/caa.2015.3544
https://doi.org/10.4995/caa.2015.3544
Autor:
Hiroki Wada, Tony Raynham, Rebekah E. Beevers, Jeremy Major, Jess Taylor, Neil Grimster, David W. Walker, Parminder Kaur Ruprah, Svenja Burckhardt, Hannah Fiona Sore, James Nally, Alison Reid, Steven P. Langston, Andrew H. Henry, Helen J. Payne, Yvonne Ferguson, John C Reader, Eva Figueroa, Michael Shaw, Abid Masood, Nawaz Mohammed Khan, Valérie Reader, Lloyd J. Payne, Kerry Jenkins, Stephen Thompson, Ruth Adams, Matthew Stirling, Richard J. Boyce, Adam C. Talbot, Gilles Raphy, Jones Mark, Robert Judkins, James M. Cobb, Justine Y.Q. Lai
Publikováno v:
Medicinal Research Reviews. 25:310-330
This work describes the preparation of approximately 13,000 compounds for rapid identification of hits in high-throughput screening (HTS). These compounds were designed as potential serine/threonine or tyrosine kinase inhibitors. The library consists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c2cfd46838ec84ce2d3ca8b3d9e0bd
https://doi.org/10.1002/med.20026
https://doi.org/10.1002/med.20026
Autor:
Owen Callaghan, Eva Figueroa, Andrew James Woodhead, Christopher William Murray, Joseph E. Coyle, Maria Grazia Carr, Martyn Frederickson, Theresa Rachael Phillips, Miles Congreve, Rachel McMenamin, Robert Downham, M. Alistair O’Brien, Alison Jo-Anne Woolford, Sahil Patel, Suzanna Cowan, Gianni Chessari, Glyn Williams, Brent Graham
Publikováno v:
Journal of medicinal chemistry. 53(16)
Inhibitors of the chaperone Hsp90 are potentially useful as chemotherapeutic agents in cancer. This paper describes an application of fragment screening to Hsp90 using a combination of NMR and high throughput X-ray crystallography. The screening iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c594310a83bc1771903a5371059bc6
https://pubmed.ncbi.nlm.nih.gov/20718493
https://pubmed.ncbi.nlm.nih.gov/20718493
Autor:
Maria Grazia Carr, Jonathan Lewis, Gary Trewartha, Ruth Feltell, Brian John Williams, Martyn Frederickson, Lina Parra, Andrew James Woodhead, Alison Jo-Anne Woolford, Joseph E. Coyle, Christopher W. Murray, Lynsey Fazal, Theresa Rachael Phillips, Donna-Michelle Smith, Rachel McMenamin, Brent Graham, Eva Figueroa, Sharna J. Rich, Gianni Chessari, M. Alistair O’Brien, Miles Congreve, Sahil Patel, Jose Cosme, David C. Rees, Robert Downham, Philip J. Day, Hayley Angove, Mladen Vinkovic
Publikováno v:
Journal of medicinal chemistry. 53(16)
Inhibitors of the molecular chaperone heat shock protein 90 (Hsp90) are currently generating significant interest in clinical development as potential treatments for cancer. In a preceding publication (DOI: 10.1021/jm100059d ) we describe Astex's app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb185c0fbb87f767299335f3ff66cf7b
https://pubmed.ncbi.nlm.nih.gov/20662534
https://pubmed.ncbi.nlm.nih.gov/20662534
Autor:
Eva Figueroa, Noelia
Publikováno v:
Revista de Filosofía UIS; jul-dic2015, Vol. 14 Issue 2, p187-207, 21p
Autor:
Andrew J. Woodhead, Hayley Angove, Maria G. Carr, Gianni Chessari, Miles Congreve, Joseph E. Coyle, Jose Cosme, Brent Graham, Philip J. Day, Robert Downham, Lynsey Fazal, Ruth Feltell, Eva Figueroa, Martyn Frederickson, Jonathan Lewis, Rachel McMenamin, Christopher W. Murray, M. Alistair OâBrien, Lina Parra, Sahil Patel
Publikováno v:
Journal of Medicinal Chemistry; Aug2010, Vol. 53 Issue 16, p5956-5969, 14p