Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Eva Ekblad"'
Autor:
Ulrikke Voss, Eva Ekblad
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114044 (2014)
ObjectiveIntestinal barrier function is vital for homeostasis. Conditions where the mucosal barrier is compromised lead to increased plasma content of lipopolysaccharide (LPS). LPS acts on Toll-like receptor 4 (TLR4) and initiates cellular inflammato
Externí odkaz:
https://doaj.org/article/58f01c1874b54013a21c538679fb2660
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81413 (2013)
OBJECTIVE: Obese and/or diabetic patients have elevated levels of free fatty acids and increased susceptibility to gastrointestinal symptoms. Since the enteric nervous system is pivotal in regulating gastrointestinal functions alterations or neuropat
Externí odkaz:
https://doaj.org/article/e6f04bf8aa3041c8aafe895c4a1f9a6d
Publikováno v:
Cell and Tissue Research. 376:189-197
In this study, a novel subset of doublecortin-like kinase 1 (DCLK1)-immunoreactive (IR) tuft cells that also contain serotonin (5-hydroxytryptamine, 5HT) is described, in terms of their number, regional distribution, possible synthesis or reuptake of
Publikováno v:
Peptides. 151:170776
Autor:
Daniel Nebel, Ulrikke Voss, Daniel Svensson, Alexandra Aidoukovitch, Emma Anders, Birgitta Agerberth, Bengt-Olof Nilsson, Fredrik Andersson, Eva Ekblad, Dan Ericson
Publikováno v:
European Journal of Oral Sciences. 126:93-100
The human host defense peptide, LL-37, is an important player in the first line of defense against invading microorganisms. LL-37 and its precursor, hCAP18, have been detected in unstimulated whole saliva but no reports showing hCAP18/LL-37 in isolat
Publikováno v:
International Journal of Experimental Pathology. 99:38-45
Reduced blood flow to the brain induces cerebral ischaemia, potentially causing central injury and peripheral complications including gastrointestinal (GI) dysfunction. The pathophysiology behind GI symptoms is suspected to be neuropathy in the enter
Publikováno v:
Cell and Tissue Research. 366:353-362
The biologically active form of vitamin D, 1α,25-dihydroxyvitamin D3 (1,25D3), has been reported to positively regulate the human cathelicidin anti-microbial peptide (CAMP) gene coding for LL-37, but the mechanisms are not completely understood. We
Publikováno v:
Autonomic Neuroscience. 193:104-107
Background Clinical observations have suggested repeated gonadotropin-releasing hormone (GnRH) exposure to cause intestinal dysfunction and loss of enteric neurons. This has been further studied and confirmed in a rat in vivo model involving iterated
Publikováno v:
Experimental cell research. 369(1)
Tuft cells are gastrointestinal (GI) sensory cells recognized by their characteristic shape and their microvilli “tuft”. Aims of the present study were to elucidate their regional distribution and spatial connections with satiety associated endoc
Autor:
Eva Ekblad, Bilal Omar, Bo Ahrén, Ulrikke Voss, J E Foley, Maria Sörhede Winzell, Jenny Vikman
Publikováno v:
Diabetologia. 56:1752-1760
Studies have shown that dipeptidyl peptidase-4 (DPP4) inhibitors stimulate insulin secretion and increase beta cell mass in rodents. However, in these models hyperglycaemia has been induced early on in life and the treatment periods have been short.