Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Eva Drazanova"'
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Akademický článek
Chronic citalopram effects on the brain neurochemical profile and perfusion in a rat model of depression detected by the NMR techniques – spectroscopy and perfusion
Autor: Iveta Harastova-Pavlova, Eva Drazanova, Lucie Kratka, Petra Amchova, Maria Hrickova, Ondrej Macicek, Jiri Vitous, Radovan Jirik, Jana Ruda-Kucerova
Publikováno v: Biomedicine & Pharmacotherapy, Vol 181, Iss , Pp 117656- (2024)
Background: Major depressive disorder (MDD) is a mental illness with a high worldwide prevalence and suboptimal pharmacological treatment, which necessitates the development of novel, more efficacious MDD medication. Nuclear magnetic resonance (NMR)
Externí odkaz: https://doaj.org/article/85ee4d08964d423eb85aabdcd0d44f41
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2
Akademický článek
Potent synergistic effects of dulaglutide and food restriction in prevention of olanzapine-induced metabolic adverse effects in a rodent model
Autor: Katerina Horska, Jan Kucera, Eva Drazanova, Gabriela Kuzminova, Petra Amchova, Maria Hrickova, Jana Ruda-Kucerova, Silje Skrede
Publikováno v: Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116763- (2024)
Background: Antipsychotics are indispensable in the treatment of severe mental illneses, however adverse metabolic effects including diabetes, weight gain, dyslipidemia, and related cardiovascular morbidity are common, and current pharmacological str
Externí odkaz: https://doaj.org/article/317d5309e5a84e589e27043d4e5ff927
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5
Olanzapine exposure diminishes perfusion and decreases volume of sensorimotor cortex in rats
Autor: Hana Kotolová, Zenon Starčuk, Katerina Horska, Zuzana Babinská, Eva Drazanova, Nadezda Vaskovicova, Radim Skoupy, Jana Ruda-Kucerova, Marcela Buchtová, Lucie Vrlíková, Lucie Krátká
Publikováno v: Pharmacological Reports. 71:839-847
Background Olanzapine is a frequently used atypical antipsychotic drug known to exert structural brain alterations in animals. This study investigated whether chronic olanzapine exposure alters regional blood brain perfusion assessed by Arterial Spin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257af4c3a83d6a5d061a7b56d61d0f35
https://doi.org/10.1016/j.pharep.2019.04.020
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6
Diffusion Kurtosis Imaging Detects Microstructural Changes in a Methamphetamine-Induced Mouse Model of Parkinson’s Disease
Autor: Zenon Starčuk, Jana Ruda-Kucerova, Alzbeta Sejnoha Minsterova, Eva Drazanova, Anas Arab, Nikoletta Szabó, Amit Khairnar, Irena Rektorová
Publikováno v: Neurotoxicity Research. 36:724-735
Methamphetamine (METH) abuse is known to increase the risk of Parkinson's disease (PD) due to its dopaminergic neurotoxicity. This is the rationale for the METH model of PD developed by toxic METH dosing (10 mg/kg four times every 2 h) which features
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103a8ed1f88eedcd54ce6bd505e12efa
https://doi.org/10.1007/s12640-019-00068-0
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7
Diffusion kurtosis imaging detects the time-dependent progress of pathological changes in the oral rotenone mouse model of Parkinson's disease
Autor: Irena Rektorová, Jana Ruda-Kucerova, Alexandra Chovsepian, Qi Shang, Zenon Starčuk, Eva Drazanova, Anas Arab, Constantinos Hadjistyllis, Nikoletta Szabó, Alzbeta Sejnoha Minsterova, Amit Khairnar, Francisco Pan-Montojo
Publikováno v: Journal of neurochemistryREFERENCES. 158(3)
Clinical diagnosis of Parkinson's disease (PD) occurs typically when a substantial proportion of dopaminergic neurons in the substantia nigra (SN) already died, and the first motor symptoms appear. Therefore, tools enabling the early diagnosis of PD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69634a3d7be0abb583729693e278d5c5
https://pubmed.ncbi.nlm.nih.gov/34107061
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9
Aripiprazole-induced adverse metabolic alterations in polyI:C neurodevelopmental model of schizophrenia in rats
Autor: Regina Demlová, Katerina Horska, Michal Karpisek, Tomáš Kašpárek, Eva Drazanova, Hana Kotolová, Jana Ruda-Kucerova
Publikováno v: Neuropharmacology. 123:148-158
Schizophrenia appears to be linked to higher incidence of metabolic syndrome even in the absence of antipsychotic treatment. Atypical antipsychotics substantially differ in their propensity to induce metabolic alterations. Aripiprazole is considered
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3aa7ee163ce4c43c6bf8d0505db50e4
https://doi.org/10.1016/j.neuropharm.2017.06.003
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10
Different effects of prenatal MAM vs. perinatal THC exposure on regional cerebral blood perfusion detected by Arterial Spin Labelling MRI in rats
Autor: Tibor Štark, Michal Maryška, Eva Drazanova, Filippo Drago, Martin Kuchar, Jana Ruda-Kucerova, Vincenzo Micale, Zenon Starčuk, Lucie Krátká
Publikováno v: Scientific Reports. 2019, vol. 9, issue 1, p. 1-10.
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Clinical studies consistently report structural impairments (i.e.: ventricular enlargement, decreased volume of anterior cingulate cortex or hippocampus) and functional abnormalities including changes in regional cerebral blood flow in individuals su
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a971e7d05561d4cd4e6d84f0550dab
https://hdl.handle.net/11012/202970
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