Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Eva Crosas"'
Autor:
Eva Crosas-Molist, Vittoria Graziani, Oscar Maiques, Pahini Pandya, Joanne Monger, Remi Samain, Samantha L. George, Saba Malik, Jerrine Salise, Valle Morales, Adrien Le Guennec, R. Andrew Atkinson, Rosa M. Marti, Xavier Matias-Guiu, Guillaume Charras, Maria R. Conte, Alberto Elosegui-Artola, Mark Holt, Victoria Sanz-Moreno
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Cell migration is crucial for cancer dissemination. We find that AMP-activated protein kinase (AMPK) controls cell migration by acting as an adhesion sensing molecular hub. In 3-dimensional matrices, fast-migrating amoeboid cancer cells exer
Externí odkaz:
https://doaj.org/article/350286488c1e4475afc3dd506fdbc8ec
Autor:
Kara A Zielinski, Andreas Prester, Hina Andaleeb, Soi Bui, Oleksandr Yefanov, Lucrezia Catapano, Alessandra Henkel, Max O. Wiedorn, Olga Lorbeer, Eva Crosas, Jan Meyer, Valerio Mariani, Martin Domaracky, Thomas A. White, Holger Fleckenstein, Iosifina Sarrou, Nadine Werner, Christian Betzel, Holger Rohde, Martin Aepfelbacher, Henry N. Chapman, Markus Perbandt, Roberto A. Steiner, Dominik Oberthuer
Publikováno v:
IUCrJ, Vol 9, Iss 6, Pp 778-791 (2022)
Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility to routinely collect data at room temperature using micrometre-sized crystals of biological macromolecules. However, SSX data collection is not yet as routi
Externí odkaz:
https://doaj.org/article/1a539044df7442e893cbada6b50b1d5b
Autor:
Charlotte M. de Winde, Samantha L. George, Eva Crosas-Molist, Yukti Hari-Gupta, Abbey B. Arp, Agnesska C. Benjamin, Lindsey J. Millward, Spyridon Makris, Alexander Carver, Valerio Imperatore, Víctor G. Martínez, Victoria Sanz-Moreno, Sophie E. Acton
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102976- (2021)
Summary: Melanoma is an aggressive skin cancer developing from melanocytes, frequently resulting in metastatic disease. Melanoma cells utilize amoeboid migration as mode of local invasion. Amoeboid invasion is characterized by rounded cell morphology
Externí odkaz:
https://doaj.org/article/4ccbb9bd840641f084f5a6f000008701
Autor:
Julia Lieske, Maximilian Cerv, Stefan Kreida, Dana Komadina, Janine Fischer, Miriam Barthelmess, Pontus Fischer, Tim Pakendorf, Oleksandr Yefanov, Valerio Mariani, Thomas Seine, Breyan H. Ross, Eva Crosas, Olga Lorbeer, Anja Burkhardt, Thomas J. Lane, Sebastian Guenther, Julian Bergtholdt, Silvan Schoen, Susanna Törnroth-Horsefield, Henry N. Chapman, Alke Meents
Publikováno v:
IUCrJ, Vol 6, Iss 4, Pp 714-728 (2019)
Efficient and reliable sample delivery has remained one of the bottlenecks for serial crystallography experiments. Compared with other methods, fixed-target sample delivery offers the advantage of significantly reduced sample consumption and shorter
Externí odkaz:
https://doaj.org/article/9cf038e492ec4349b8a7aa1396ce04ee
Autor:
Remi Samain, Samantha George, Jaume Barcelo, Leonie Kohlhammer, Jose L. Orgaz, Eva Crosas-Molist, Victoria Sanz-Moreno, Oscar Maiques
Publikováno v:
Physiological Reviews. 102:455-510
Rho GTPases are a family of small G proteins that regulate a wide array of cellular processes related to their key roles controlling the cytoskeleton. Cancer is a multistep disease caused by the accumulation of genetic mutations and epigenetic altera
Autor:
Victoria Sanz-Moreno, Eva Crosas-Molist Crosas-Molist, Oscar Maiques, Vittoria Graziani, Pahini Pandya, Jo Monger, REmi Samain, Samantha George, Saba Malik, Jerrine Salise, Adrien Le_guennec, Robert Atkinson, Maria Conte, Mark Holt, Guillaume Charras
Cell migration are crucial for development, immunity and cancer dissemination. We find that AMPK controls cell migration by acting as an adhesion sensing molecular hub. In 3-dimensional (3D) matrices, fast migrating amoeboid cancer cells exert low ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968014fa3353a555c8cb2acb9591d2a3
https://doi.org/10.21203/rs.3.rs-1653312/v1
https://doi.org/10.21203/rs.3.rs-1653312/v1
Autor:
Christina S Kamma-Lorger, Christian Pinali, Juan Carlos Martínez, Jon Harris, Robert D Young, Cecilie Bredrup, Eva Crosas, Marc Malfois, Eyvind Rødahl, Keith M Meek, Carlo Knupp
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147948 (2016)
The role of Decorin in organising the extracellular matrix was examined in normal human corneas and in corneas from patients with Congenital Stromal Corneal Dystrophy (CSCD). In CSCD, corneal clouding occurs due to a truncating mutation (c.967delT) i
Externí odkaz:
https://doaj.org/article/2dc78dd99a2947dda0328e8160d7b867
Publikováno v:
Acta Crystallographica Section D Structural Biology. 76:971-981
The addition of compounds to scavenge the radical species produced during biological small-angle X-ray scattering (BioSAXS) experiments is a common strategy to reduce the effects of radiation damage and produce better quality data. As almost half of
Autor:
Alexander Carver, Spyridon Makris, Víctor G. Martínez, Valerio Imperatore, Yukti Hari-Gupta, Charlotte M. de Winde, Sophie E. Acton, Abbey B. Arp, Agnesska C. Benjamin, Samantha L. George, Eva Crosas-Molist, Lindsey J. Millward, Victoria Sanz-Moreno
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102976-(2021)
iScience
iScience
Summary Melanoma is an aggressive skin cancer developing from melanocytes, frequently resulting in metastatic disease. Melanoma cells utilize amoeboid migration as mode of local invasion. Amoeboid invasion is characterized by rounded cell morphology
Autor:
Eva Crosas-Molist, Lena Boehme, Faraz K. Mardakheh, Bruce Fanshawe, Jose L. Orgaz, Gilbert O. Fruhwirth, Irene Rodriguez-Hernandez, Victoria Sanz-Moreno, Oscar Maiques, Gaia Cantelli, Alessia Volpe
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
British Journal of Cancer
BRITISH JOURNAL OF CANCER
instname
British Journal of Cancer
BRITISH JOURNAL OF CANCER
© The Author(s) 2021.
[Background]: Metastasis is a hallmark of cancer and responsible for most cancer deaths. Migrastatics were defined as drugs interfering with all modes of cancer cell invasion and thus cancers’ ability to metastasise. Fir
[Background]: Metastasis is a hallmark of cancer and responsible for most cancer deaths. Migrastatics were defined as drugs interfering with all modes of cancer cell invasion and thus cancers’ ability to metastasise. Fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0245a51b1650d282bfda2f05b9dbaede
http://hdl.handle.net/10261/264785
http://hdl.handle.net/10261/264785