Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eva Chenail"'
Autor:
Darrell Panza, Kristine Svenson, Jason Shaoyun Xiang, Xianbin Tian, Christian E. Johnson, Xin Xu, James Tobin, Xiangping Li, Huan-Qiu Li, Mylene Perreault, Joel Bard, Tarek S. Mansour, Seung Hahm, Eddine Saiah, Ariful Qadri, Vipin Suri, Eva Chenail, Zhao-Kui Wan, Manus Ipek, Yuzhe Xing
Publikováno v:
Journal of Medicinal Chemistry. 52:5449-5461
Cortisol and the glucocorticoid receptor signaling pathway have been implicated in the development of diabetes and obesity. The reduction of cortisone to cortisol is catalyzed by 11beta-hydroxysteroid dehydrogenase type I (11beta-HSD1). 2,4-Disubsitu
Autor:
Tarek S. Mansour, Mylene Perreault, Joel Bard, Eva Chenail, Xianbin Tian, James F. Tobin, Xiangping Li, Jason Shaoyun Xiang, Zhao-Kui Wan, Xin Xu, Manus Ipek, Darrell Panza, Kristine Svenson, Huan-Qiu Li, Eddine Saiah, Ariful Qadri, Vipin Suri, Mengmeng Wang, Christian E. Johnson, Seung Hahm
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoid cortisone to its active form, cortisol. The glucocorticoid receptor (GR) signaling pathway has been linked to the pathophysiology of diabetes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac55ea3454d8d6acc241eb07df394729
https://europepmc.org/articles/PMC4027441/
https://europepmc.org/articles/PMC4027441/
Synthesis of potent and orally efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitor HSD-016
Autor:
Huan-Qiu Li, S. Mansour Tarek, Zhao-Kui Wan, Wang Youchu, Walter W. Massefski, Christopher Kendall, Eddine Saiah, Stéphane Gingras, Jason Shaoyun Xiang, Eva Chenail
Publikováno v:
The Journal of organic chemistry. 76(17)
Cortisol and the glucocorticoid receptor (GR) signaling pathway has been linked to the development of diabetes and metabolic syndrome. In vivo, 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive cortisone to its
Autor:
Zhao-Kui Wan, Eva Chenail, Jason Xiang, Huan-Qiu Li, Manus Ipek, Joel Bard, Kristine Svenson, Tarek S. Mansour, Xin Xu, Xianbin Tian, Vipin Suri, Seung Hahm, Yuzhe Xing, Christian E. Johnson, Xiangping Li, Ariful Qadri, Darrell Panza, Mylene Perreault, James F. Tobin, Eddine Saiah
Publikováno v:
Journal of Medicinal Chemistry; Sep2009, Vol. 52 Issue 17, p5449-5461, 13p
Phosphonium- and Benzotriazolyloxy-Mediated Bond-Forming Reactions and Their Synthetic Applications.
Publikováno v:
Synlett; 2010, Issue 8, p1143-1169, 27p