Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Eva Bober"'
Autor:
Tatsuya Yoshizawa, Yoshifumi Sato, Shihab U. Sobuz, Tomoya Mizumoto, Tomonori Tsuyama, Md. Fazlul Karim, Keishi Miyata, Masayoshi Tasaki, Masaya Yamazaki, Yuichi Kariba, Norie Araki, Eiichi Araki, Shingo Kajimura, Yuichi Oike, Thomas Braun, Eva Bober, Johan Auwerx, Kazuya Yamagata
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Sirtuins have been reported to positively regulate brown adipose tissue thermogenesis. Here the authors report that brown adipocytic SIRT7 suppresses whole-body energy expenditure and thermogenesis in mice, potentially by attenuating batokine gene ex
Externí odkaz:
https://doaj.org/article/7b51c06d17574f72b35f0b3884a3c7fe
Autor:
Angelina M. Georgieva, Xinyue Guo, Marek Bartkuhn, Stefan Günther, Carsten Künne, Christian Smolka, Ann Atzberger, Ulrich Gärtner, Kamel Mamchaoui, Eva Bober, Yonggang Zhou, Xuejun Yuan, Thomas Braun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Utrophin is a dystrophin-related protein stabilizing the sarcolemma in absence of dystrophin. Here the authors report that inactivation of the protein deacetylase SIRT6, involved in the deacetylation of the epigenetic mark H3K56ac in muscle cells, in
Externí odkaz:
https://doaj.org/article/f98f5858e11c424f9ecb03f39cf07309
Autor:
Masatoshi Fukuda, Tatsuya Yoshizawa, Md. Fazlul Karim, Shihab U. Sobuz, Wataru Korogi, Daiki Kobayasi, Hiroki Okanishi, Masayoshi Tasaki, Katsuhiko Ono, Tomohiro Sawa, Yoshifumi Sato, Mami Chirifu, Takeshi Masuda, Teruya Nakamura, Hironori Tanoue, Kazuhisa Nakashima, Yoshihiro Kobashigawa, Hiroshi Morioka, Eva Bober, Sumio Ohtsuki, Yuriko Yamagata, Yukio Ando, Yuichi Oike, Norie Araki, Shu Takeda, Hiroshi Mizuta, Kazuya Yamagata
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
SP7/Osterix is a transcription factor involved in osteoblast differentiation. Here, the authors show that Sirtuin 7 activates Osterix posttranslationally by regulating its lysine acylation, and that mice lacking Sirtuin 7 in osteoblasts show reduced
Externí odkaz:
https://doaj.org/article/5d154c78ddfa43f09911b245d2d21134
Autor:
Irene Santos-Barriopedro, Laia Bosch-Presegué, Anna Marazuela-Duque, Carolina de la Torre, Carlota Colomer, Berta N. Vazquez, Thomas Fuhrmann, Bárbara Martínez-Pastor, Wenfu Lu, Thomas Braun, Eva Bober, Thomas Jenuwein, Lourdes Serrano, Manel Esteller, Zhenbang Chen, Silvia Barceló-Batllori, Raúl Mostoslavsky, Lluis Espinosa, Alejandro Vaquero
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Sirtuins are involved in the regulation of responses to diverse types of cellular stress. Here the authors describe the SirT6-dependent cysteine monoubiquitination of the histone methyltransferase Suv39h1 as part of a regulatory circuit for the NF-κ
Externí odkaz:
https://doaj.org/article/5703e4bf0087489eaecd2013c1eb52d7
Autor:
Annalisa Buniello, Rachel E Hardisty-Hughes, Johanna C Pass, Eva Bober, Richard J Smith, Karen P Steel
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56274 (2013)
The recessive mouse mutant headbobber (hb) displays the characteristic behavioural traits associated with vestibular defects including headbobbing, circling and deafness. This mutation was caused by the insertion of a transgene into distal chromosome
Externí odkaz:
https://doaj.org/article/8c63d1aab8a343f39d05222242db5f9f
Autor:
Naomi Nakagata, Satoru Yamamura, Taishi Nakamura, Kazuya Yamagata, Masahiro Yamamoto, Eiichiro Yamamoto, Yoichi Sunagawa, Yuichiro Arima, Kenji Sakamoto, Eva Bober, Yuichi Kimura, Shinsuke Hanatani, Koichi Kaikita, Thomas Braun, Yasuhiro Izumiya, Satoshi Araki, Yoshiro Onoue, Toshihiro Yamada, Kenichi Tsujita, Tatsuya Yoshizawa, Toshifumi Ishida, Tatsuya Morimoto
Publikováno v:
Hypertension. 75:98-108
Sirt (Sirtuin) 7, the most recently identified mammalian sirtuin, has been shown to contribute to appropriate wound healing processes after acute cardiovascular insult. However, its role in the development of cardiac remodeling after pressure overloa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c372ea422acefeaee5b9ed8a83419907
https://doi.org/10.1161/hypertensionaha.119.13357
https://doi.org/10.1161/hypertensionaha.119.13357
Autor:
Shinsuke Hanatani, Koichi Kaikita, Kazuya Yamagata, Taishi Nakamura, Naomi Nakagata, Satoru Yamamura, Eiichiro Yamamoto, Yuichi Kimura, Kenichi Tsujita, Shokei Kim-Mitsuyama, Tatsuya Yoshizawa, Yuichiro Arima, Eva Bober, Thomas Braun, Toshifumi Ishida, Masataka Sata, Yoshiro Onoue, Satoshi Araki, Yasuhiro Izumiya, Takafumi Senokuchi
Publikováno v:
Circulation journal : official journal of the Japanese Circulation Society. 85(12)
Background: Sirt7 is a recently identified sirtuin and has important roles in various pathological conditions, including cancer progression and metabolic disorders. It has previously been reported that Sirt7 is a key molecule in acute myocardial woun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273d919db417185062d825e23f43851c
https://pubmed.ncbi.nlm.nih.gov/33762514
https://pubmed.ncbi.nlm.nih.gov/33762514
Autor:
Daniela Popescu, Alessandro Ianni, Poonam Kumari, Marcus Krüger, Claudia Fiorillo, Andreas J. Schmidt, Shijing Yue, Alejandro Vaquero, Soraya Hölper, Nicolas G. Simonet, Eva Bober, Shahriar Tarighi, Christian Smolka, Thomas Braun, Stefan Guenther
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Proc Natl Acad Sci U S A
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Proc Natl Acad Sci U S A
Adaptation to different forms of environmental stress is crucial for maintaining essential cellular functions and survival. The nucleolus plays a decisive role as a signaling hub for coordinating cellular responses to various extrinsic and intrinsic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489d71847621b68f7d5860acefb5d22b
https://doi.org/10.1073/pnas.2015339118
https://doi.org/10.1073/pnas.2015339118
Publikováno v:
Pediatric Cardiology
Cardiovascular diseases represent a major cause of death and morbidity. Cardiac and vascular pathologies develop predominantly in the aged population in part due to lifelong exposure to numerous risk factors but are also found in children and during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fefae0bf4acf6d17618bc3cd0d3c1e
http://europepmc.org/articles/PMC5958173
http://europepmc.org/articles/PMC5958173
Publikováno v:
Biochemical and Biophysical Research Communications. 492:434-440
Maintenance of highly compact heterochromatin at ribosomal DNA (rDNA) segments is essential to prevent homologous recombination between rDNA repeats and for preserving genomic stability and nucleolar architecture. Here, we investigated the role of Si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab0a1a85a17857e571593fdd685f80b
https://doi.org/10.1016/j.bbrc.2017.08.081
https://doi.org/10.1016/j.bbrc.2017.08.081