Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eva Bettens"'
Autor:
Piet Wigerinck, Maryam Ehteshami, Jerome Deval, Bertrand Van Schoubroeck, Tania Ivens, Marcia Van Ginderen, Eva Bettens, Dirk Jochmans, Matthias Götte, Inky De Baere, Pascale Dehertogh, Kurt Hertogs, Bart Rudolf Romanie Kesteleyn, Herwig Van Marck
Publikováno v:
Journal of Virology. 80:12283-12292
We have discovered a novel class of human immunodeficiency virus (HIV) reverse transcriptase (RT) inhibitors that block the polymerization reaction in a mode distinct from those of the nucleoside or nucleotide RT inhibitors (NRTIs) and nonnucleoside
Autor:
Géry Dams, Rudi Pauwels, Kurt Hertogs, Christel Van den Eynde, Erik Nijs, Eva Bettens, Tania Ivens, Asa Ohagen, Koen Van Acker
Publikováno v:
Journal of Virological Methods
The severity and global spread of the 2003 outbreak of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) highlighted the risks to human health posed by emerging viral diseases and emphasized the need for specific therapeutic age
Autor:
Christophe Gabriel Marcel Demestre, Benoit Antoine Schmitt, Céline Isabelle Mordant, Laurence Queguiner, C. Masungi, Paul J. Lewi, Jerome Emile Georges Guillemont, Elisabeth Thérèse Jeanne Pasquier, Anik Peeters, Liesbeth Smeulders, Kurt Hertogs, Eva Bettens, Jan Heeres
Publikováno v:
European journal of medicinal chemistry. 42(5)
Novel diarylpyrimidines (DAPY), which represent next generation of non-nucleoside reverse transcriptase inhibitors (NNRTIs), were synthesized and their activities against human immunodeficiency virus type I (HIV-1) assessed. Modulations at positions
Autor:
Frits Daeyaert, Lucien Maria Henricus Koymans, Patrice Palandjian, Marie-Pierre de Béthune, Elisabeth Thérèse Jeanne Pasquier, Sandrine Gaurrand, Eddy Arnold, Maarten Vinkers, R Pauwels, Koen Andries, Piet Wigerinck, Daniel F J Vernier, Paul J. Lewi, Marc René De Jonge, Kalyan Das, Eva Bettens, Jan Heeres, Kurt Hertogs, Jerome Emile Georges Guillemont, Philip Timmerman, Paul Adriaan Jan Janssen
Publikováno v:
Journal of medicinal chemistry
This paper reports the synthesis and the antiviral properties of new diarylpyrimidine (DAPY) compounds as nonnucleoside reverse transcriptase inhibitors (NNRTIs). The synthesis program around this new DAPY series was further optimized to produce comp