Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Eva Berghausen"'
Autor:
Martin Mollenhauer, Senai Bokredenghel, Simon Geißen, Anna Klinke, Tobias Morstadt, Merve Torun, Sabrina Strauch, Wibke Schumacher, Martina Maass, Jürgen Konradi, Vera B. M. Peters, Eva Berghausen, Marius Vantler, Stephan Rosenkranz, Dennis Mehrkens, Simon Braumann, Felix Nettersheim, Alexander Hof, Sakine Simsekyilmaz, Holger Winkels, Volker Rudolph, Stephan Baldus, Matti Adam, Henrik ten Freyhaus
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The six-transmembrane protein of prostate 2 (Stamp2) acts as an anti-inflammatory protein in macrophages by protecting from overt inflammatory signaling and Stamp2 deficiency accelerates atherosclerosis in mice. Herein, we describe an unexpected role
Externí odkaz:
https://doaj.org/article/19b28f4d94d949c4b63ace97d42ca06e
Autor:
Miguel A. Alejandre Alcazar, Henrik ten Freyhaus, M Zierden, Dickson W.L. Wong, Christine Joseph, Leoni L. Gnatzy-Feik, Stephan Baldus, Rajkumar Savai, Jean J. Zhao, Anna Klinke, Ralph T. Schermuly, Soni Savai Pullamsetti, Arnica Behringer, Wiebke Janssen, Max Krause, Marius Vantler, Eva Berghausen, Peter Boor, Stephan Rosenkranz
Publikováno v:
J Clin Invest
Enhanced signaling via RTKs in pulmonary hypertension (PH) impedes current treatment options because it perpetuates proliferation and apoptosis resistance of pulmonary arterial smooth muscle cells (PASMCs). Here, we demonstrated hyperphosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e49f43982802a26f06f13689188e6ea
https://doi.org/10.1172/jci136939
https://doi.org/10.1172/jci136939
Publikováno v:
European Heart Journal. 42
Rationale Pulmonary arterial hypertension (PAH) is a vascular disease characterized by chronic increases in pulmonary vascular resistance (PVR), pulmonary arterial pressure (PAP), and right ventricular (RV) hypertrophy. Increased activation of recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cf0d1757b10e8a27d9b6fea215e0730
https://doi.org/10.1093/eurheartj/ehab724.3422
https://doi.org/10.1093/eurheartj/ehab724.3422
Autor:
Stephan Baldus, Eva Berghausen, Martin Mollenhauer, Stephan Rosenkranz, Dennis Mehrkens, Marius Vantler, Matti Adam, M Zierden
Publikováno v:
European Heart Journal. 41
Background In smooth muscle cells (SMCs), the PI 3-kinase isoform p110α mediates receptor tyrosine kinase dependent proliferation, chemotaxis and cell survival. Since mice, harbouring a smooth muscle specific p110α deficiency (SM-p110α−/−), di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998a71f127cbeaf4b8f25947dc75b02e
https://doi.org/10.1093/ehjci/ehaa946.2315
https://doi.org/10.1093/ehjci/ehaa946.2315
Autor:
M Zierden, L Feik, Stephan Rosenkranz, Eva Berghausen, Stephan Baldus, C Millarg, Marius Vantler
Publikováno v:
European Heart Journal. 41
Introduction and purpose Atherosclerosis is a chronic inflammatory disease of arteries, critically involving leukocytes like macrophages as well as T and B lymphocytes. Macrophages are major drivers of disease through the ingestion of lipoproteins, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9012f734612ab0184360008376f638b
https://doi.org/10.1093/ehjci/ehaa946.3749
https://doi.org/10.1093/ehjci/ehaa946.3749
Autor:
M Zierden, L Feik, Emilio Hirsch, Marius Vantler, Stephan Rosenkranz, Eva Berghausen, Stephan Baldus
Publikováno v:
European Heart Journal. 41
Introduction Pulmonary hypertension (PH) is a pulmonary vascular disease that is associated with unacceptably high morbidity and mortality. PH is characterized by chronically increased pulmonary arterial pressure, increased pulmonary vascular resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea94181f12d3e09db9710ac340e962cc
https://doi.org/10.1093/ehjci/ehaa946.3811
https://doi.org/10.1093/ehjci/ehaa946.3811
Autor:
Ralph T. Schermuly, M Batool, Stephan Rosenkranz, Henrik ten Freyhaus, M Zierden, Stephan Baldus, Eva Berghausen, Marius Vantler
Publikováno v:
Basic Research in Cardiology
Six-transmembrane protein of prostate (Stamp2) protects from diabetes and atherosclerosis in mice via anti-inflammatory mechanisms. As chronic inflammation is a hallmark of pulmonary arterial hypertension (PAH), we investigated the role of Stamp2. St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91e27670eb6c10668dc086f5e3b581d
https://pubmed.ncbi.nlm.nih.gov/33188479
https://pubmed.ncbi.nlm.nih.gov/33188479
Publikováno v:
European Heart Journal. 40
Rationale Pulmonary arterial hypertension (PAH) is characterized by vascular remodeling in pulmonary arterioles. Increased activation of receptor tyrosine kinase (RTK)-mediated signaling pathways lead to increased proliferation and chemotaxis of pulm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6443e52e0134f89a48bc68bc215a9df
https://doi.org/10.1093/eurheartj/ehz748.0685
https://doi.org/10.1093/eurheartj/ehz748.0685
Publikováno v:
European Heart Journal. 40
Introduction and purpose Atherosclerosis is a chronic inflammatory disease of arteries and represents the main underlying cause of death worldwide. Macrophages are major drivers of atherosclerosis by ingestion of lipoproteins, foam cell formation, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a553e942df25dcf0e48414275cbd0472
https://doi.org/10.1093/eurheartj/ehz745.0714
https://doi.org/10.1093/eurheartj/ehz745.0714
Autor:
M Zierden, H. ten Freyhaus, Stephan Baldus, Eva Berghausen, Stephan Rosenkranz, Marius Vantler, M Batool
Publikováno v:
European Heart Journal. 40
Background The six-transmembrane protein of prostate (Stamp2) is a potent anti-inflammatory player in adipocytes and also in macrophages. Stamp2's actions in these cells protects from diet-induced diabetes and from atherosclerosis mice. As chronic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65e962f8cad64cd583b8f792b47dd1b0
https://doi.org/10.1093/eurheartj/ehz745.0718
https://doi.org/10.1093/eurheartj/ehz745.0718