Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eva Balaziova"'
Publikováno v:
Biomedical Papers, Vol 161, Iss 3, Pp 252-260 (2017)
Background and Aims: Proteolytic enzymes contribute to the progression of various cancers. We previously reported increased expression of the proline specific peptidases dipeptidyl peptidase-IV (DPP-IV) and its closest paralogue fibroblast activation
Externí odkaz:
https://doaj.org/article/8d539186030f41528aaa015a42a4c056
Autor:
Evzen Krepela, Zdislava Vanickova, Petr Hrabal, Michal Zubal, Barbora Chmielova, Eva Balaziova, Petr Vymola, Ivana Matrasova, Petr Busek, Aleksi Sedo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1046 (2021)
The proline-specific serine protease fibroblast activation protein (FAP) can participate in the progression of malignant tumors and represents a potential diagnostic and therapeutic target. Recently, we demonstrated an increased expression of FAP in
Externí odkaz:
https://doaj.org/article/9c1abe665d8a440eb7a05833f56f2e28
Autor:
Petr Busek, Rosana Mateu, Karla Svobodova, Zuzana Zemanova, R. Tomas, Aleksi Sedo, P Hrabal, Petr Vymola, D Netuka, Eva Balaziova
Publikováno v:
Neuro Oncol
BACKGROUND Increased expression of fibroblast activation protein (FAP) is characteristic for several cancer types including human glioblastomas (GBM). FAP is expressed on both cancer as well as stromal cells which were demonstrated in extracranial tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f432b384c56346a8615c2c97be4a055a
https://europepmc.org/articles/PMC8427329/
https://europepmc.org/articles/PMC8427329/
Autor:
Petr Busek, Martin Syrucek, Ivana Matrasova, Robert Tomas, Jaromir Belacek, Marek Hilser, Evzen Krepela, Aleksi Sedo, Eva Balaziova, Zuzana Zemanova
Publikováno v:
Scopus-Elsevier
Glioblastomas are deadly neoplasms resistant to current treatment modalities. Fibroblast activation protein (FAP) is a protease which is not expressed in most of the normal adult tissues but is characteristically present in the stroma of extracranial
Publikováno v:
Europe PubMed Central
BACKGROUND: Fibroblast activation protein (FAP) is a protease selectively expressed in a number of extracranial cancers especially in cancer associated fibroblasts (CAF). CAF play an important role in the pathogenesis of malignant tumors through extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1640c96d762f1ef3f9866c8233ce0e
https://europepmc.org/articles/PMC6144288/
https://europepmc.org/articles/PMC6144288/
Autor:
Jarmila Stremenova, Petr Busek, Eva Balaziova, Evzen Krepela, Aleksi Sedo, Lucie Sromova, Hynek Strnad, Dalibor Kosek, Marek Hilser, Jana Trylcova
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 44:738-747
Malignant gliomas exhibit abnormal expression of proteolytic enzymes that may participate in the uncontrolled cell proliferation and aberrant interactions with the brain extracellular matrix. The multifunctional membrane bound serine aminopeptidase d
Autor:
Petr Busek, Lucie Sromova, Libuse Lizcova, Jarmila Stremenova, Evzen Krepela, Aleksi Sedo, Eva Balaziova
Publikováno v:
Molecular and Cellular Biochemistry. 354:283-289
Dipeptidyl peptidase-IV (DPP-IV) and fibroblast activation protein-α (FAP) are speculated to participate in the regulation of multiple biological processes, because of their unique enzymatic activity, as well as by non-hydrolytic molecular interacti
Publikováno v:
Clinica Chimica Acta. 411:1046-1050
Background Dipeptidyl peptidase-IV (DPP-IV) enzymatic activity controls biological halftime of multiple local mediators. Its deregulation is associated with pathogenesis of several autoimmune diseases, including rheumatoid arthritis (RA). Although DP
Autor:
Lucie Sromova, Evzen Krepela, Aleksi Sedo, Marek Hilser, Eva Balaziova, I. Vomelova, Petr Busek
Publikováno v:
Europe PubMed Central
Fibroblast activation protein alpha (FAP) is a dual specificity serine protease that is strongly associated with the development and progression of human carcinomas and represents a potential stromal target for anticancer treatment. Due to its gelati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a234d97c31058a53b61082936fd190
https://europepmc.org/articles/PMC4185866/
https://europepmc.org/articles/PMC4185866/
Autor:
Evzen Krepela, Aleksi Sedo, Marek Hilser, Petr Busek, R. Tomas, Eva Balaziova, M. Syrucek, Ivana Matrasova, Zuzana Zemanova
Publikováno v:
Europe PubMed Central