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pro vyhledávání: '"Eva Avila-Munoz"'
Autor:
Ana C. Valencia-Olvera, Deebika Balu, Naomi Faulk, Aspasia Amiridis, Yueting Wang, Christine Pham, Eva Avila-Munoz, Jason M. York, Gregory R. J. Thatcher, Mary Jo LaDu
Publikováno v:
Neurotherapeutics.
APOE4, encoding apolipoprotein E4 (apoE4), is the greatest genetic risk factor for Alzheimer’s disease (AD), compared to the common APOE3. While the mechanism(s) underlying APOE4-induced AD risk remains unclear, increasing the lipidation of apoE4 i