Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Eva Asp"'
Autor:
Irina A. Antonijevic, Brian R. Bettencourt, Peter Bialek, Pei Ge, Shi-Ying Ding, George Lai, Joseph Hedde, Eva Asp, Meetu Seth, George Marnellos, Katharine A. Whartenby, Darren G. Monckton, Sarah J. Tabrizi
Huntington disease (HD) is one of a growing number of rare genetic diseases characterized by the inheritance of an increased number of short tandem repeats within the affected gene. Many of these repeat expansion disorders (REDs) affect the brain. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb4d0a6d166957fe956c4e881986c53
https://eprints.gla.ac.uk/269853/1/269853.pdf
https://eprints.gla.ac.uk/269853/1/269853.pdf
Autor:
Michal Lulu, Rajaraman Krishnan, Cassandra Rockwell-Postel, Haim Tsubery, Ming Proschitsky, Eva Asp
Publikováno v:
Journal of Molecular Biology. 431:1920-1939
The M13 tip protein, g3p, binds the C-terminal domain of the bacterial membrane protein TolA via β-sheet augmentation, facilitating viral entry into Escherichia coli. G3p binding leads to rearrangement of the β strands and partial unfolding of TolA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a96567e5459b1c517c09b4fac289bc7
https://doi.org/10.1016/j.jmb.2019.03.022
https://doi.org/10.1016/j.jmb.2019.03.022
Autor:
Edward Holgate, Michal Lulu, Jason Wright, Jonathan M. Levenson, Cassandra Rockwell-Postel, Richard Fisher, Eva Asp, Kim McDowell, Charlotte Chung, Rajaraman Krishnan, Ming Proschitsky, Haim Tsubery
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d84e65e6902a2363792963c3ceaef2a
https://doi.org/10.1016/j.jalz.2017.06.1400
https://doi.org/10.1016/j.jalz.2017.06.1400
Publikováno v:
Mechanisms of Development. 131:137-149
The Hedgehog pathway plays important roles in embryonic development, adult stem cell maintenance and tumorigenesis. In mammals these effects are mediated by Sonic, Desert and Indian Hedgehog (Shh, Dhh and Ihh). Shh undergoes autocatalytic cleavage an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6014042cd0ae23981434645b6a57ce22
https://doi.org/10.1016/j.mod.2013.12.002
https://doi.org/10.1016/j.mod.2013.12.002
Publikováno v:
Eukaryotic Cell. 7:328-338
Signaling by stress-activated mitogen-activated protein kinase (MAPK) pathways influences translation efficiency in mammalian cells and budding yeast. We have investigated the stress-activated MAPK from fission yeast, Sty1, and its downstream protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e417d9e91c438493d47c66141c47aea
https://doi.org/10.1128/ec.00358-07
https://doi.org/10.1128/ec.00358-07
Autor:
Michal Lulu, Michael Grundman, Richard Fisher, Edward Rockenstien, Sharon Gilead, Beka Solomon, Rajaraman Krishnan, Jason Wright, Eliezer Masliah, Muhamad Nadeem, Michelle Gray, Jenna C. Carroll, Sally Schroeter, Franz Hefti, Eva Asp, Haim Tsubery, Elliott J. Mufson, Myra Gartner, Jonathan M. Levenson, Valerie Cullen, Ming Proschitsky, Kimberley Gannon
Publikováno v:
Alzheimer's & Dementia. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f11c1cfe0b1239b85d23d234e8131c
https://doi.org/10.1016/j.jalz.2015.07.051
https://doi.org/10.1016/j.jalz.2015.07.051
Autor:
Jonathan M. Levenson, Valerie Cullen, Eliezer Masliah, Michal Lulu, Myra Gartner, Richard Fisher, Haim Tsubery, Elliott J. Mufson, Jason Wright, Rajaraman Krishnan, Sally Schroeter, Kimberley Gannon, Beka Solomon, Sharon Gilead, Ming Proschitsky, Edward Rockenstein, Jenna C. Carroll, Muhammad Nadeem, Jonathon Waltho, Peter Davis, David G. Myszka, Eva Asp
Publikováno v:
Alzheimer's & Dementia. 10
antioxidants (GSH and catalase activities) were assessed. Furthermore, the Kaplan-Meier test was used to calculate the average life expectancy. Results: 3xTgAD mice showed lower values of macrophage functions, lymphocyte chemotaxis, NK cells proporti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c77aeaae83f6d44c38fbd7dcf3c951e3
https://doi.org/10.1016/j.jalz.2014.05.741
https://doi.org/10.1016/j.jalz.2014.05.741
Autor:
Ming Proschitsky, Haim Tsubery, Shadiyat Shoaga, Hemraj B. Dodiya, Jenna C. Carroll, Richard Fisher, Beka Solomon, Sally Schroeter, Muhammad Nadeem, Jonathan M. Levenson, Valerie Cullen, Eva Asp, Rajaraman Krishnan, Elliott J. Mufson, Kimberley Gannon
Publikováno v:
Alzheimer's & Dementia. 10
for the development of both symptom modifying and disease modifying therapeutics. Tau oligomers are toxic to neurons, inhibit long term potentiation in hippocampal slices, impair the formation of associative fear memory in mice, and induce the propag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0b6cc891bf5a02f9336bb3837162ea4
https://doi.org/10.1016/j.jalz.2014.05.1731
https://doi.org/10.1016/j.jalz.2014.05.1731
Autor:
Myra Gartner, Peter Davis, Haim Tsubery, Beka Solomon, Jason Wright, Michal Lulu, Andrea M. Hounslow, Richard Fisher, Daniel A. Kirschner, Ming Proschitsky, Jonathan P. Waltho, Sharon Gilead, Rajaraman Krishnan, David G. Myszka, Hideyo Inouye, Eva Asp
Publikováno v:
Journal of molecular biology. 426(13)
Misfolded protein aggregates, characterized by a canonical amyloid fold, play a central role in the pathobiology of neurodegenerative diseases. Agents that bind and sequester neurotoxic intermediates of amyloid assembly, inhibit the assembly or promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7e5e9ef92159d0775713b560b34f8d
https://pubmed.ncbi.nlm.nih.gov/24768993
https://pubmed.ncbi.nlm.nih.gov/24768993
Publikováno v:
Gene. 243:11-18
SMGB and PSP are among the most abundant products of the immature acinar cells in developing rat parotid and submandibular glands and are also products of the sublingual gland serous demilunes. Previous analysis of Smgb and Psp cDNA clones demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7595faadf448d7883e369b47d2d6b071
https://doi.org/10.1016/s0378-1119(99)00538-7
https://doi.org/10.1016/s0378-1119(99)00538-7