Proteoglycans involved in bidirectional communication between mast cells and hippocampal neurons

Autor: Juan Antonio Flores, María Pilar Ramírez-Ponce, María Ángeles Montes, Santiago Balseiro-Gómez, Jorge Acosta, Guillermo Álvarez de Toledo, Eva Alés

Publikováno v: Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)

Abstract Background Mast cells (MCs) in the brain can respond to environmental cues and relay signals to neurons that may directly influence neuronal electrical activity, calcium signaling, and neurotransmission. MCs also express receptors for neurot

Externí odkaz: https://doaj.org/article/0c1407c252134a37b6521c505c5e0cf2

Mast Cell Changes the Phenotype of Microglia via Histamine and ATP

Autor: Juan A. Flores, Jorge Acosta, M.D. Maldonado, Santiago Balseiro-Gomez, María Pilar Ramírez-Ponce, Alejandro Sola-Garcia, Eva Alés

Publikováno v: Cellular Physiology and Biochemistry, Vol 55, Iss 1, Pp 17-32 (2021)

BACKGROUND/AIMS: Microglia are the dynamic motile phagocytes of the brain considered the first line of defense against threats or disturbances to the Central Nervous System (CNS). Microglia help orchestrate the immunological response by interacting w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cda82e5b15cefa3b7b5f8f0f57b411
https://doi.org/10.33594/000000324

The human-specific duplicated α7 gene inhibits the ancestral α7, negatively regulating nicotinic acetylcholine receptor-mediated transmitter release

Autor: Gema Atienza, Eva Alés, Arturo Chávez-Reyes, Carolina Martín-Sánchez, Francisco Arnalich, José Luis Cedillo, Anna Bordas, Santiago Balseiro-Gomez, Carmen Montiel, María Extremera

Publikováno v: The Journal of Biological Chemistry

Gene duplication generates new functions and traits, enabling evolution. Human-specific duplicated genes in particular are primary sources of innovation during our evolution although they have very few known functions. Here we examine the brain funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a881750a98efc25dc22b75c59d0177a
http://europepmc.org/articles/PMC7949125

Proteoglycans involved in bidirectional communication between mast cells and hippocampal neurons

Autor: María Pilar Ramírez-Ponce, María Ángeles Montes, Guillermo Alvarez de Toledo, Santiago Balseiro-Gomez, Juan A. Flores, Jorge Acosta, Eva Alés

Publikováno v: idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Journal of Neuroinflammation
idUS. Depósito de Investigación de la Universidad de Sevilla
instname

Background: Mast cells (MCs) in the brain can respond to environmental cues and relay signals to neurons that may directly influence neuronal electrical activity, calcium signaling, and neurotransmission. MCs also express receptors for neurotransmitt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3f6ad35aec819bbe40c8832420563a
https://doi.org/10.1186/s12974-019-1504-6

Identification of a New Exo-Endocytic Mechanism Triggered by Corticotropin-Releasing Hormone in Mast Cells

Autor: Santiago Balseiro-Gomez, Eva Alés, M. Pilar Ramirez-Ponce, Juan A. Flores, Jorge Acosta

Publikováno v: The Journal of Immunology. 195:2046-2056

The key role of mast cells (MC), either in development of inflammatory pathologies or in response to environmental stress, has been widely reported in recent years. Previous studies have described the effects of corticotropin-releasing hormone (CRH),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372e059579f32728bbbaa8951c7de61f
https://doi.org/10.4049/jimmunol.1500253