Výsledky vyhledávání - "Eva Aguado Roca"

TRIAD3/RNF216 E3 ligase specifically synthesises K63-linked ubiquitin chains and is inactivated by mutations associated with Gordon Holmes syndrome

Autor: Meike Broemer, Lukas Schwintzer, Eva Aguado Roca

Publikováno v: Cell death discovery 5(1), 75 (2019). doi:10.1038/s41420-019-0158-6
Cell Death Discovery, Vol 5, Iss 1, Pp 1-11 (2019)
Cell Death Discovery

TRIAD3/RNF216 is a ubiquitin ligase of the RING-in-between-RING family. Recent publications identified TRIAD3 mutations in patients with neurological diseases, including Gordon Holmes syndrome and Huntington-like disorder. To understand the functiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a182e73c07a310b3dde6ba5475504849
https://pub.dzne.de/record/140619

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New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules

Autor: Susanne Schoch, Lukas Schwintzer, Ana-Maria Oprişoreanu, Marc Sylvester, Stanislav Vinopal, Eva Aguado Roca, Frank Bradke, Richa Das, Meike Broemer

Publikováno v: Journal of cell science 132(12), jcs229252 (2019). doi:10.1242/jcs.229252
Journal of Cell Science

Mechanisms that regulate the formation of membrane-less cellular organelles, such as neuronal RNA granules and stress granules, have gained increasing attention over the past years. These granules consist of RNA and a plethora of RNA-binding proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72354ae616046248ea9c7dbc33f77f1d
https://pub.dzne.de/record/140782

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The de-ubiquitylating enzyme DUBA is essential for spermatogenesis in Drosophila

Autor: Eli Arama, Timo Glatter, Meike Broemer, Juliane Melzer, Eva Aguado Roca, Lisa Koerver, Dominic Teichert

Publikováno v: Cell death and differentiation 23(12), 2019-2030 (2016). doi:10.1038/cdd.2016.79

De-ubiquitylating enzymes (DUBs) reverse protein ubiquitylation and thereby control essential cellular functions. Screening for a DUB that counteracts caspase ubiquitylation to regulate cell survival, we identified the Drosophila ovarian tumour-type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803440b53f89b9fce2f07f5337b468e0
https://pub.dzne.de/record/138902

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