Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eva A. Enyedy"'
Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells
Autor:
Kateryna Ohui, Iryna Stepanenko, Iuliana Besleaga, Maria V. Babak, Radu Stafi, Denisa Darvasiova, Gerald Giester, Vivien Pósa, Eva A. Enyedy, Daniel Vegh, Peter Rapta, Wee Han Ang, Ana Popović-Bijelić, Vladimir B. Arion
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1336 (2020)
Thiosemicarbazones continue to attract the interest of researchers as potential anticancer drugs. For example, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, or triapine, is the most well-known representative of this class of compounds that has
Externí odkaz:
https://doaj.org/article/f157861451a146cbb48e29d7fa7d856e
Autor:
Miljan N. M. Milunović, Oleg Palamarciuc, Angela Sirbu, Sergiu Shova, Dan Dumitrescu, Dana Dvoranová, Peter Rapta, Tatsiana V. Petrasheuskaya, Eva A. Enyedy, Gabriella Spengler, Marija Ilic, Harald H. Sitte, Gert Lubec, Vladimir B. Arion
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1213 (2020)
A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged trimethylammonium moiety ([H2LR]Cl, R = H, Me, Et, Ph) and four copper(II) complexes [Cu(HLR)Cl]Cl (1–4) were synthesised with the aim to study (i) their an
Externí odkaz:
https://doaj.org/article/2f59fdd67b2d49deb7893def752b1b9a
Autor:
Tamás Pivarcsik, Jakob Kljun, Sergio Clemente Rodriguez, David Cortéz Alcaraz, Uroš Rapuš, Márta Nové, Egon F Várkonyi, József Nyári, Anita Bogdanov, Gabriella Spengler, Iztok Turel, Éva A. Enyedy
Publikováno v:
ACS Omega, Vol 9, Iss 44, Pp 44601-44615 (2024)
Externí odkaz:
https://doaj.org/article/f1f1d15106bb40fa9469648a4a03909f
Publikováno v:
Cancer Research. 83:4901-4901
α-N-Heterocyclic thiosemicarbazones (TSCs) have long been investigated as anticancer compounds. Triapine is one of the best-known TSCs for anticancer therapy and is currently tested in a clinical phase III trial. To further improve the anticancer ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b94b7a3747c1a2db62ae0f5621c3dc3
https://doi.org/10.1158/1538-7445.am2023-4901
https://doi.org/10.1158/1538-7445.am2023-4901
Autor:
Christopher, Wittmann, Felix, Bacher, Eva A, Enyedy, Orsolya, Dömötör, Gabriella, Spengler, Christian, Madejski, Jóhannes, Reynisson, Vladimir B, Arion
Publikováno v:
Journal of medicinal chemistry. 65(3)
A series of latonduine and indoloquinoline derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cdeebaf24923ccd6d9b31a2ed60f697
https://pubmed.ncbi.nlm.nih.gov/35104137
https://pubmed.ncbi.nlm.nih.gov/35104137
Autor:
Éva A. Enyedy, Anett Giricz, Tatsiana V. Petrasheuskaya, János P. Mészáros, Nóra V. May, Gabriella Spengler, Ferenc Kovács, Barnabás Molnár, Éva Frank
Publikováno v:
Inorganics, Vol 12, Iss 2, p 49 (2024)
Steroids are often considered valuable molecular tools for the development of anticancer agents with improved pharmacological properties. Conjugation of metal chelating moieties with a lipophilic sterane backbone is a viable option to obtain novel an
Externí odkaz:
https://doaj.org/article/3f5173af62d34b5d961088bee0f4d261
Autor:
Nádia Ribeiro, Ipek Bulut, Baris Sergi, Vivien Pósa, Gabriella Spengler, Giuseppe Sciortino, Vânia André, Liliana P. Ferreira, Tarita Biver, Valeria Ugone, Eugenio Garribba, João Costa-Pessoa, Éva A. Enyedy, Ceyda Acilan, Isabel Correia
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
We report the synthesis and characterization of a group of benzoylhydrazones (Ln) derived from 2-carbaldehyde-8-hydroxyquinoline and benzylhydrazides containing distinct para substituents (R = H, Cl, F, CH3, OCH3, OH and NH2, for L1-7, respectively;
Externí odkaz:
https://doaj.org/article/39d0a688871541ab8b5f628dd3f7dc53
Autor:
Ana Isabel, Tomaz, Tamás, Jakusch, Tânia S, Morais, Fernanda, Marques, Rodrigo F M, de Almeida, Filipa, Mendes, Eva A, Enyedy, Isabel, Santos, João Costa, Pessoa, Tamás, Kiss, M Helena, Garcia
Publikováno v:
Journal of inorganic biochemistry. 117
Ruthenium complexes hold great potential as alternatives to cisplatin in cancer chemotherapy. We present results on the in vitro antitumor activity of an organometallic 'Ru(II)Cp' complex, [Ru(II)Cp(bipy)(PPh(3))][CF(3)SO(3)], designated as TM34 (PPh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8a587f55b4693c0eeca2f5278520b8a
https://pubmed.ncbi.nlm.nih.gov/22877927
https://pubmed.ncbi.nlm.nih.gov/22877927
Autor:
János P. Mészáros, Wolfgang Kandioller, Gabriella Spengler, Alexander Prado-Roller, Bernhard K. Keppler, Éva A. Enyedy
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 356 (2023)
Cancer chemotherapeutics usually have serious side effects. Targeting the special properties of cancer and activation of the anticancer drug in the tumor microenvironment in situ may decrease the intensity of the side effects and improve the efficacy
Externí odkaz:
https://doaj.org/article/f6ed983c09f24f838afa3157fcb3179c
Autor:
Tatsiana V. Petrasheuskaya, Ferenc Kovács, Nóra Igaz, Andrea Rónavári, Bálint Hajdu, Laura Bereczki, Nóra V. May, Gabriella Spengler, Béla Gyurcsik, Mónika Kiricsi, Éva Frank, Éva A. Enyedy
Publikováno v:
Molecules, Vol 28, Iss 1, p 54 (2022)
A series of novel estradiol-based salicylaldehyde (thio)semicarbazones ((T)SCs) bearing (O,N,S) and (O,N,O) donor sets and their Cu(II) complexes were developed and characterized in detail by 1H and ¹³C nuclear magnetic resonance spectroscopy, UV
Externí odkaz:
https://doaj.org/article/8955a198063c498eaca85577a98baf1a