Výsledky vyhledávání - "Eva A S Koster"

Akademický článek

DNA barcoded peptide-MHC multimers to measure and monitor minor histocompatibility antigen-specific T cells after allogeneic stem cell transplantation

Autor: Sine R Hadrup, Marieke Griffioen, J H Frederik Falkenburg, Mirjam H M Heemskerk, Marian van de Meent, Michel G D Kester, Kyra J Fuchs, Marcus Göransson, Natasja W Ettienne, Rob C M de Jong, Eva A S Koster, Constantijn J M Halkes, Ferenc Scheeren, Peter van Balen

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 12 (2024)

Allogeneic stem cell transplantation (alloSCT) provides a curative treatment option for hematological malignancies. After HLA-matched alloSCT, donor-derived T cells recognize minor histocompatibility antigens (MiHAs), which are polymorphic peptides p

Externí odkaz: https://doaj.org/article/5ad0d9de316d4c61a49201b465e22f42

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Akademický článek

Risk factors for graft-versus-host-disease after donor lymphocyte infusion following T-cell depleted allogeneic stem cell transplantation

Autor: Eva A. S. Koster, Peter A. von dem Borne, Peter van Balen, Erik W. A. Marijt, Jennifer M. L. Tjon, Tjeerd J. F. Snijders, Daniëlle van Lammeren, Hendrik Veelken, J. H. Frederik Falkenburg, Constantijn J. M. Halkes, Liesbeth C. de Wreede

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionUnmodified donor lymphocyte infusions (DLI) after allogeneic stem cell transplantation (alloSCT) can boost the beneficial Graft-versus-Leukemia (GvL) effect but may also induce severe Graft-versus-Host-Disease (GvHD). To improve the balan

Externí odkaz: https://doaj.org/article/f91495ebee1a4669a0b7b64a4d0daa90

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Akademický článek

Joint models quantify associations between immune cell kinetics and allo-immunological events after allogeneic stem cell transplantation and subsequent donor lymphocyte infusion

Autor: Eva A. S. Koster, Edouard F. Bonneville, Peter A. von dem Borne, Peter van Balen, Erik W. A. Marijt, Jennifer M. L. Tjon, Tjeerd J. F. Snijders, Daniëlle van Lammeren, Hendrik Veelken, Hein Putter, J. H. Frederik Falkenburg, Constantijn J. M. Halkes, Liesbeth C. de Wreede

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Alloreactive donor-derived T-cells play a pivotal role in alloimmune responses after allogeneic hematopoietic stem cell transplantation (alloSCT); both in the relapse-preventing Graft-versus-Leukemia (GvL) effect and the potentially lethal complicati

Externí odkaz: https://doaj.org/article/80d6d14acc53406c9e680ff7959ef80a

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Akademický článek

The added value of multi‐state modelling in a randomized controlled trial: The HOVON 102 study re‐analyzed

Autor: Katerina Bakunina, Hein Putter, Jurjen Versluis, Eva A. S. Koster, Bronno van derHolt, Markus G. Manz, Dimitri A. Breems, Bjorn T. Gjertsen, Jacqueline Cloos, Peter J. M. Valk, Jakob Passweg, Thomas Pabst, Gert J. Ossenkoppele, Bob Löwenberg, Jan J. Cornelissen, Liesbeth C. deWreede

Publikováno v: Cancer Medicine, Vol 11, Iss 3, Pp 630-640 (2022)

Abstract Clofarabine is an active antileukemic drug for subgroups of patients with acute myeloid leukemia (AML). Multi‐state models can provide additional insights to supplement the original intention‐to‐treat analysis of randomized controlled

Externí odkaz: https://doaj.org/article/efddc38d4b904e3199e4f5412bc60ca2

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Akademický článek

Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity

Autor: Aicha Laghmouchi, Michel G. D. Kester, Conny Hoogstraten, Lois Hageman, Wendy de Klerk, Wesley Huisman, Eva A. S. Koster, Arnoud H. de Ru, Peter van Balen, Sebastian Klobuch, Peter A. van Veelen, J. H. Frederik Falkenburg, Inge Jedema

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

In the context of HLA-DP-mismatched allogeneic stem cell transplantation, mismatched HLA-DP alleles can provoke profound allo-HLA-DP-specific immune responses from the donor T-cell repertoire leading to graft-versus-leukemia effect and/or graft-versu

Externí odkaz: https://doaj.org/article/d97ad938d6f94d7bbb24d680cfd08676

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Tracking the Progeny of Virus-specific T-cell Products in Patients Post-Transplant using TCR-Sequencing

Autor: Wesley, Huisman, Marthe C J, Roex, Lois, Hageman, Eva A S, Koster, Sabrina A J, Veld, Conny, Hoogstraten, Peter, van Balen, H M Esther, van Egmond, Cornelis A M, Van Bergen, Hermann, Einsele, Lothar, Germeroth, Derk, Amsen, J H Frederik, Falkenburg, Inge, Jedema

Publikováno v: Blood advances.

Adoptive cellular therapies with T cells are increasingly used to treat a variety of conditions. For instance, in a recent phase I/II trial, we prophylactically administered multi-virus-specific T-cell products to protect recipients of T-cell deplete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c6fc3eca857b2870dcc8146b8a290a1f
https://pubmed.ncbi.nlm.nih.gov/36121440

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The added value of multi-state modelling in a randomized controlled trial

Autor: Katerina Bakunina, Hein Putter, Jurjen Versluis, Eva A. S. Koster, Bronno Holt, Markus G. Manz, Dimitri A. Breems, Bjorn T. Gjertsen, Jacqueline Cloos, Peter J. M. Valk, Jakob Passweg, Thomas Pabst, Gert J. Ossenkoppele, Bob Löwenberg, Jan J. Cornelissen, Liesbeth C. Wreede

Publikováno v: Bakunina, Katerina; Putter, Hein; Versluis, Jurjen; Koster, Eva A S; van der Holt, Bronno; Manz, Markus G; Breems, Dimitri A; Gjertsen, Bjorn T; Cloos, Jacqueline; Valk, Peter J M; Passweg, Jakob; Pabst, Thomas; Ossenkoppele, Gert J; Löwenberg, Bob; Cornelissen, Jan J; de Wreede, Liesbeth C (2022). The added value of multi-state modelling in a randomized controlled trial: The HOVON 102 study re-analyzed. Cancer medicine, 11(3), pp. 630-640. Wiley 10.1002/cam4.4392
Cancer Medicine, 11(3), 630-640. WILEY
Cancer Medicine, Vol 11, Iss 3, Pp 630-640 (2022)
Cancer Medicine
Cancer Medicine, 11(3), 630-640. John Wiley & Sons Ltd.
Bakunina, K, Putter, H, Versluis, J, Koster, E A S, van der Holt, B, Manz, M G, Breems, D A, Gjertsen, B T, Cloos, J, Valk, P J M, Passweg, J, Pabst, T, Ossenkoppele, G J, Löwenberg, B, Cornelissen, J J & de Wreede, L C 2021, ' The added value of multi-state modelling in a randomized controlled trial : The HOVON 102 study re-analyzed ', Cancer Medicine . https://doi.org/10.1002/cam4.4392
Cancer Medicine. John Wiley and Sons Ltd

Clofarabine is an active antileukemic drug for subgroups of patients with acute myeloid leukemia (AML). Multi-state models can provide additional insights to supplement the original intention-to-treat analysis of randomized controlled trials (RCT). W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d2b76eb855955a9ca323a31f9fbcc8
https://hdl.handle.net/1887/3276352

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