Výsledky vyhledávání - "Eva A, Enyedy"

Akademický článek

Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells

Autor: Kateryna Ohui, Iryna Stepanenko, Iuliana Besleaga, Maria V. Babak, Radu Stafi, Denisa Darvasiova, Gerald Giester, Vivien Pósa, Eva A. Enyedy, Daniel Vegh, Peter Rapta, Wee Han Ang, Ana Popović-Bijelić, Vladimir B. Arion

Publikováno v: Biomolecules, Vol 10, Iss 9, p 1336 (2020)

Thiosemicarbazones continue to attract the interest of researchers as potential anticancer drugs. For example, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, or triapine, is the most well-known representative of this class of compounds that has

Externí odkaz: https://doaj.org/article/f157861451a146cbb48e29d7fa7d856e

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

Autor: Miljan N. M. Milunović, Oleg Palamarciuc, Angela Sirbu, Sergiu Shova, Dan Dumitrescu, Dana Dvoranová, Peter Rapta, Tatsiana V. Petrasheuskaya, Eva A. Enyedy, Gabriella Spengler, Marija Ilic, Harald H. Sitte, Gert Lubec, Vladimir B. Arion

Publikováno v: Biomolecules, Vol 10, Iss 9, p 1213 (2020)

A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged trimethylammonium moiety ([H2LR]Cl, R = H, Me, Et, Ph) and four copper(II) complexes [Cu(HLR)Cl]Cl (1–4) were synthesised with the aim to study (i) their an

Externí odkaz: https://doaj.org/article/2f59fdd67b2d49deb7893def752b1b9a

Zobrazit plný text záznamu

Plný text ve formátu HTML

Abstract 4901: The role of protein disulfide isomerase and copper in the paraptotic cell death of clinically investigated anticancer thiosemicarbazones

Autor: Sonja Hager, Walter Berger, Christian R. Kowol, Eva A. Enyedy, Petra Heffeter

Publikováno v: Cancer Research. 83:4901-4901

α-N-Heterocyclic thiosemicarbazones (TSCs) have long been investigated as anticancer compounds. Triapine is one of the best-known TSCs for anticancer therapy and is currently tested in a clinical phase III trial. To further improve the anticancer ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b94b7a3747c1a2db62ae0f5621c3dc3
https://doi.org/10.1158/1538-7445.am2023-4901

Zobrazit plný text záznamu

Akademický článek

Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors

Autor: Eva Anna Enyedy, Orsolya Dömötör, Attila Borics, Bernhard K. Keppler, Christian R. Kowol

Publikováno v: Proceedings, Vol 22, Iss 1, p 27 (2019)

Binding interactions between human serum albumin and four clinically approved epidermal [...]

Externí odkaz: https://doaj.org/article/8e7e66176d3e426780ea14e967a9b920

Zobrazit plný text záznamu

[RuII(η⁵-C₅H₅)(bipy)(PPh₃)]⁺, a promising large spectrum antitumor agent: cytotoxic activity and interaction with human serum albumin

Autor: Ana Isabel, Tomaz, Tamás, Jakusch, Tânia S, Morais, Fernanda, Marques, Rodrigo F M, de Almeida, Filipa, Mendes, Eva A, Enyedy, Isabel, Santos, João Costa, Pessoa, Tamás, Kiss, M Helena, Garcia

Publikováno v: Journal of inorganic biochemistry. 117

Ruthenium complexes hold great potential as alternatives to cisplatin in cancer chemotherapy. We present results on the in vitro antitumor activity of an organometallic 'Ru(II)Cp' complex, [Ru(II)Cp(bipy)(PPh(3))][CF(3)SO(3)], designated as TM34 (PPh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8a587f55b4693c0eeca2f5278520b8a
https://pubmed.ncbi.nlm.nih.gov/22877927

Zobrazit plný text záznamu