Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eva Rached"'
Autor:
Aldert H. Piersma, Rex E. FitzGerald, Manuela Tiramani, Florianne Monnet-Tschudi, Helena T. Hogberg, Gabriele Schmuck, Ellen Fritsche, Anna Bal-Price, Sandra Allen, Marcel Leist, Nathalie Delrue, Thomas Hartung, Martin Paparella, Daniela Maria Oggier, Timo Ylikomi, Timo Buetler, Eva Rached, Walter Lichtensteiger, Benoît Schilter, Susanne Hougaard Bennekou, Marta Axelstad, Michael Arand, Kevin M. Crofton, Martin F. Wilks, Tuula Heinonen, Luc Stoppini, Enrico Tongiorgi
Publikováno v:
Bal-Price, A, Crofton, K M, Leist, M, Allen, S, Arand, M, Buetler, T, Delrue, N, FitzGerald, R E, Hartung, T, Heinonen, T, Hogberg, H, Bennekou, S H, Lichtensteiger, W, Oggier, D, Paparella, M, Petersen, M A, Piersma, A, Rached, E, Schilter, B, Schmuck, G, Stoppini, L, Tongiorgi, E, Tiramani, M, Monnet-Tschudi, F, Wilks, M F, Ylikomi, T & Fritsche, E 2015, ' International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes ', Archives of Toxicology, vol. 89, no. 2, pp. 269-287 . https://doi.org/10.1007/s00204-015-1464-2
Archives of Toxicology, vol. 89, no. 2, pp. 269-287
Archives of Toxicology
Archives of Toxicology, vol. 89, no. 2, pp. 269-287
Archives of Toxicology
A major problem in developmental neurotoxicity (DNT) risk assessment is the lack of toxicological hazard information for most compounds. Therefore, new approaches are being considered to provide adequate experimental data that allow regulatory decisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5930c858834c129b367351d4e39bee46
https://doi.org/10.1007/s00204-015-1464-2
https://doi.org/10.1007/s00204-015-1464-2
Publikováno v:
Carcinogenesis. 30:711-719
Ochratoxin A (OTA) is a potent renal carcinogen, but little is known regarding the mechanism of OTA carcinogenicity. Early histopathological alterations induced by OTA in rat kidney include single cell death, stimulation of cell proliferation and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43bf474133451dc658a3bbc67e0efce
https://doi.org/10.1093/carcin/bgp049
https://doi.org/10.1093/carcin/bgp049
Publikováno v:
Toxicological Sciences. 103:371-381
The kidney is one of the main targets of xenobiotic-induced toxicity, but early detection of renal damage is difficult. Recently, several novel biomarkers of nephrotoxicity have been identified by transcription profiling, including kidney injury mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607d6904f452b307f2e42383b4d09ec2
https://doi.org/10.1093/toxsci/kfn040
https://doi.org/10.1093/toxsci/kfn040
Autor:
John J. Callanan, Heidrun Ellinger-Ziegelbauer, Arnd Brandenburg, Melanie Adler, William M. Gallagher, Katja Matheis, Alexandra Sposny, Joseph V. Bonventre, Frank Dieterle, Wolfgang Dekant, Frank Staedtler, Dana Hoffmann, Vishal S. Vaidya, Jean C. Gautier, Eva Rached, Angela Mally, Philip G. Hewitt, Laoighse Mulrane
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 116(1)
The kidney is one of the main targets of drug toxicity, but early detection of renal damage is often difficult. As part of the InnoMed PredTox project, a collaborative effort aimed at assessing the value of combining omics technologies with conventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d117aa1aeacdc7146df5a208febeccdd
https://pubmed.ncbi.nlm.nih.gov/20118187
https://pubmed.ncbi.nlm.nih.gov/20118187
Autor:
Silvia Wagner, Alexander Amberg, Angela Mally, Eva Rached, Maximilian Sieber, Wolfgang Dekant
Publikováno v:
Chemical research in toxicology. 22(7)
For early detection of toxicity and improved mechanistic understanding, GC/MS-, 1H NMR-, and LC/MS-based metabonomics were applied to urine samples from a rodent toxicity study on the mycotoxin and renal carcinogen ochratoxin A (OTA). OTA was adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17c07cb341269b258436ec62fc251d8
https://pubmed.ncbi.nlm.nih.gov/19610676
https://pubmed.ncbi.nlm.nih.gov/19610676
Autor:
John J. Callanan, Angela Mally, Wolfgang Dekant, Dana Hoffmann, Matthew B. Clement, Joseph V. Bonventre, Alexander Amberg, Eva Rached, Max Sieber, Nadine Zidek, Vishal S. Vaidya, Melanie Adler
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 109(2)
Although early detection of toxicant induced kidney injury during drug development and chemical safety testing is still limited by the lack of sensitive and reliable biomarkers of nephrotoxicity, omics technologies have brought enormous opportunities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93339f133314128795230703ea0457f8
https://pubmed.ncbi.nlm.nih.gov/19349640
https://pubmed.ncbi.nlm.nih.gov/19349640
Autor:
Werner K. Lutz, Regina Draheim, Angela Mally, Wolfgang Dekant, Ulrich Steger, Sibel Ozden, Kai Blumbach, Klaus Weber, Gordon C. Hard, Eva Rached
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 97(2)
Ochratoxin A (OTA) is nephrotoxic and a potent renal carcinogen. Male rats are most susceptible to OTA toxicity, and chronic administration of OTA (70 and 210 microg/kg bw) for 2 years has been shown to induce high incidences of adenomas and carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff97ef699c751ee4f8a70db53df4779f
https://pubmed.ncbi.nlm.nih.gov/17344223
https://pubmed.ncbi.nlm.nih.gov/17344223
Publikováno v:
Carcinogenesis; Apr2009, Vol. 30 Issue 4, p711-719, 9p
Autor:
Max Sieber, Dana Hoffmann, Melanie Adler, Vishal S. Vaidya, Matthew Clement, Joseph V. Bonventre, Nadine Zidek, Eva Rached, Alexander Amberg, John J. Callanan, Wolfgang Dekant, Angela Mally
Publikováno v:
Toxicological Sciences; Jun2009, Vol. 109 Issue 2, p336-336, 1p
Publikováno v:
Toxicological Sciences; Jun2008, Vol. 103 Issue 2, p371-371, 1p