Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Eva, Severinson"'
Autor:
Natalija Gerasimčik, Minghui He, Carin I. M. Dahlberg, Nikolai V. Kuznetsov, Eva Severinson, Lisa S. Westerberg
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The Rho GTPases Cdc42, Rac1, and Rac2 coordinate receptor signaling to cell adhesion, migration, and proliferation. Deletion of Rac1 and Rac2 early during B cell development leads to failure in B cell entry into the splenic white pulp. Here, we sough
Externí odkaz:
https://doaj.org/article/e33076fef44b4b5c82948d2d89d2d338
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
We sought to identify genes necessary to induce cytoskeletal change in B cells. Using gene expression microarray, we compared B cells stimulated with interleukin-4 (IL-4) and anti-CD40 antibodies that induce B cell spreading, cell motility, tight agg
Externí odkaz:
https://doaj.org/article/1031b4ffff70428283bc588be3caf0e8
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1821
B-cell migration and adhesion are critical to form a germinal center response, the site for B-cell production of high-affinity antibodies. Here, we describe two assays that can be used to examine B-cell cytoskeletal responses needed during the germin
Publikováno v:
Methods in Molecular Biology ISBN: 9781493986118
B-cell migration and adhesion are critical to form a germinal center response, the site for B-cell production of high-affinity antibodies. Here, we describe two assays that can be used to examine B-cell cytoskeletal responses needed during the germin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f100bbe1a16f88dbace15eeb55c0ce
https://doi.org/10.1007/978-1-4939-8612-5_16
https://doi.org/10.1007/978-1-4939-8612-5_16
Autor:
Michel J. Massaad, Raif S. Geha, Carin I. M. Dahlberg, Eva Severinson, Natalija Gerasimcik, Lisa S. Westerberg, Marisa A. P. Baptista
Publikováno v:
The Journal of Immunology. 194:4750-4758
The Rho GTPase Cdc42 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the Wiskott–Aldrich syndrome protein. We sought to define the role of intrinsic expression of Cdc42 by mature B cells in their activ
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
We sought to identify genes necessary to induce cytoskeletal change in B cells. Using gene expression microarray, we compared B cells stimulated with Interleukin-4 (IL-4) and anti-CD40 antibodies that induce B cell spreading, cell motility, tight agg
Publikováno v:
Frontiers in Immunology
We sought to identify genes necessary to induce cytoskeletal change in B cells. Using gene expression microarray, we compared B cells stimulated with interleukin-4 (IL-4) and anti-CD40 antibodies that induce B cell spreading, cell motility, tight agg
Autor:
Benjamin Leveau, George Klein, Noémi Nagy, Dorina Ujvari, Monika Adori, Eva Severinson, Liang Wu, Loránd L. Kis, Minghui He, Eva Klein, Daniel Salamon, Peter Bönelt
Publikováno v:
Cytokine. 57:360-371
Type I interferons (IFN) exert multiple effects on both the innate and adaptive immune system in addition to their antiviral and antiproliferative activities. Little is known, however about the direct effects of type I IFNs on germinal center (GC) B
Publikováno v:
Blood. 109:159-167
Germline (GL) transcription is regulated by specific promoters and immunoglobulin heavy chain (IgH) 3′ locus enhancers and is necessary for Ig class-switch recombination (CSR). We have generated different transgenic lines containing the GL ϵ promo
Autor:
Carmen Salvadores Fernandez, Samantha J. Hardy, Eva Severinson, Malin Larsson, Adrian J. Thrasher, Lisa S. Westerberg
Publikováno v:
Blood. 105:1144-1152
The Wiskott-Aldrich syndrome protein (WASp) is mutated in the severe immunodeficiency disease Wiskott-Aldrich syndrome (WAS). The function of B cells and the physiologic alterations in WAS remain unclear. We show that B cells from WAS patients exhibi