Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eva, Pindurová"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveThe cytochrome P450 2D6 (CYP2D6) is an enzyme involved in the oxidative biotransformation of various widely used drugs, including paroxetine, a substrate and strong inhibitor of the enzyme. The aim is to report on a case of protracted intoxi
Externí odkaz:
https://doaj.org/article/2cd9ad09c4e149d49221e554bad51256
Autor:
Ondřej Zendulka, Eva Pindurová, Richard Barteček, Tomáš Kašpárek, J. Jurica, A. Zourkova, Alexandra Šulcová
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 37:486-490
What is known and Objective: Accurate prediction of actual CYP2D6 metabolic activity may prevent some adverse drug reactions and improve therapeutic response in patients receiving CYP2D6 substrates. Dextromethorphan-to-dextrorphan metabolic ratio (MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d39250cb60189fd7b0e8aed39ec6e43
https://doi.org/10.1111/j.1365-2710.2012.01333.x
https://doi.org/10.1111/j.1365-2710.2012.01333.x
Autor:
Eva Pindurová, Michaela Cvanová, Alexandra Žourková, Ondřej Slanař, Jiří Jarkovský, Ivana Palčíková
Publikováno v:
Journal of sexmarital therapy. 39(1)
Paroxetine-induced sexual dysfunction represents a frequent treatment complication of otherwise efficient antidepressants. The genetic polymorphism of pharmacokinetic genes may contribute to the occurrence of such dysfunctions. This study presents th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bbf418053aa0c66ca2ffe91abc1ac9
https://pubmed.ncbi.nlm.nih.gov/23152970
https://pubmed.ncbi.nlm.nih.gov/23152970
Publikováno v:
Molecular biotechnology. 53(1)
High-resolution melting curve analysis (HRM) of polymerase chain reaction (PCR) amplicons has been described as a fast, cheap, and reliable closed-tube method of genotyping with no need for labeled primers or labeled probes. We adapted this melting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a15602fae85ca96e23cd9b147f43fd
https://pubmed.ncbi.nlm.nih.gov/22367691
https://pubmed.ncbi.nlm.nih.gov/22367691
Autor:
Richard, Barteček, Jan, Juřica, Jana, Zrůstová, Tomáš, Kašpárek, Eva, Pindurová, Alexandra, Žourková
Publikováno v:
Neuro endocrinology letters. 33(2)
The objective of this prospective, naturalistic study, conducted in first-episode psychosis patients from a Central-European population, was to assess the utility of Cytochrome P-450 2D6 (CYP2D6) genotype testing under normal clinical setting.A total
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d907e44f012ec91e9d95648135c5f0e
https://pubmed.ncbi.nlm.nih.gov/22592207
https://pubmed.ncbi.nlm.nih.gov/22592207