Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Eva, Hadaschik"'
Autor:
Johanna Matull, Jan-Malte Placke, Georg Lodde, Anne Zaremba, Jochen Utikal, Patrick Terheyden, Claudia Pföhler, Rudolf Herbst, Alexander Kreuter, Julia Welzel, Julia Kretz, Inga Möller, Antje Sucker, Annette Paschen, Elisabeth Livingstone, Lisa Zimmer, Eva Hadaschik, Selma Ugurel, Dirk Schadendorf, Carl Maximilian Thielmann, Klaus Georg Griewank
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundScreening for gene mutations has become routine clinical practice across numerous tumor entities, including melanoma. BAP1 gene mutations have been identified in various tumor types and acknowledged as a critical event in metastatic uveal m
Externí odkaz:
https://doaj.org/article/ffb5dcdffd0f4202acd393d8e273a129
Autor:
Oskar Krueger, Robin Eisenburger, Alpaslan Tasdogan, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Sarah Theurer, Berthold Brodin, Dirk Schadendorf, Selma Ugurel
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Melanoma causes the majority of skin cancer-related deaths. Despite novel therapy options, metastatic melanoma still has a poor prognosis. Immune checkpoint inhibition (ICI) therapy has been shown to prolong overall survival in patients with advanced
Externí odkaz:
https://doaj.org/article/2dc0c31a91ef40a985a8c6019dc6fbb7
Autor:
Jan‐Malte Placke, Maximilian Zahn, Hannah Zillikens, Frederik Krefting, Georg C. Lodde, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Antje Sucker, Alexander Roesch, Alpaslan Tasdogan, Nalini K. Srinivas, Dirk Schadendorf, Jürgen C. Becker, Selma Ugurel
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 4, Pp 810-818 (2023)
Abstract Background Merkel cell carcinoma (MCC) is one of the deadliest skin cancers. Despite existing national guidelines, treatment of MCC patients is not as well standardized as for more common skin cancers. Objectives The study objective was to i
Externí odkaz:
https://doaj.org/article/188049c65be2447ba65d4615d59cda63
Autor:
Carl M. Thielmann, Antje Kampmeier, Alma Küchler, Martin Zenker, Ilse Wieland, Johanna Matull, Frederik Krefting, Klaus Griewank, Eva Hadaschik
Publikováno v:
JEADV Clinical Practice, Vol 1, Iss 4, Pp 416-419 (2022)
Abstract Giant congenital melanocytic naevi (CMN) are large melanocytic lesions commonly associated with neurologic abnormalities. Patients diagnosed with giant melanocytic naevi are at an increased risk of developing melanoma compared to patients wi
Externí odkaz:
https://doaj.org/article/7604a5c3f0f944a1a79aca15ca67cb6e
Autor:
Jan-Malte Placke, Mona Kimmig, Klaus Griewank, Rudolf Herbst, Patrick Terheyden, Jochen Utikal, Claudia Pföhler, Jens Ulrich, Alexander Kreuter, Peter Mohr, Ralf Gutzmer, Friedegund Meier, Edgar Dippel, Julia Welzel, Daniel Robert Engel, Sophia Kreft, Antje Sucker, Georg Lodde, Frederik Krefting, Ingo Stoffels, Joachim Klode, Alexander Roesch, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Jürgen C. Becker, Michael Weichenthal, Alpaslan Tasdogan, Dirk Schadendorf, Selma Ugurel
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104774- (2023)
Summary: Background: PD-1-based immune checkpoint inhibition (ICI) is the major backbone of current melanoma therapy. Tumor PD-L1 expression represents one of few biomarkers predicting ICI therapy outcome. The objective of the present study was to sy
Externí odkaz:
https://doaj.org/article/2d744a8eed3741f3b79556e7478f0af0
Autor:
Antje Sucker, Iris Helfrich, Luiza Martins Nascentes Melo, Dayana Herrera-Rios, Daniel Hinze, Stefanie Löffek, Irem Oezel, Juliane Klein, Sonia Leonardelli, Isa-Vanessa Westedt, Yahya Al-Matary, Sara Egea-Rodriguez, Alexandra Brenzel, Maja Bau, Eva Hadaschik, Florian Wirsdörfer, Niklas Uhlenbrock, Daniel Rauh, Joanna Poźniak, Florian Rambow, Jean-Christophe Marine, Maike Effern, Nicole Glodde, Jadwiga Jablonska
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Background Immune responses against tumors are subject to negative feedback regulation. Immune checkpoint inhibitors (ICIs) blocking Programmed cell death protein 1 (PD-1), a receptor expressed on T cells, or its ligand PD-L1 have significantly impro
Externí odkaz:
https://doaj.org/article/eb05894568da4d9e909a3aa7f4f8edb4
Autor:
Tanja Klaus, Alicia S. Wilson, Elisabeth Vicari, Eva Hadaschik, Matthias Klein, Sara Salome Clara Helbich, Nadine Kamenjarin, Katrin Hodapp, Jenny Schunke, Maximilian Haist, Florian Butsch, Hans Christian Probst, Alexander H. Enk, Karsten Mahnke, Ari Waisman, Monika Bednarczyk, Matthias Bros, Tobias Bopp, Stephan Grabbe
Publikováno v:
JCI Insight, Vol 7, Iss 24 (2022)
Leukocyte adhesion deficiency type 1 (LAD-1) is a rare disease resulting from mutations in the gene encoding for the common β-chain of the β2-integrin family (CD18). The most prominent clinical symptoms are profound leukocytosis and high susceptibi
Externí odkaz:
https://doaj.org/article/e28c3e696f2746a1a0b61970c4320b2c
Autor:
Jan-Malte Placke, Camille Soun, Jenny Bottek, Rudolf Herbst, Patrick Terheyden, Jochen Utikal, Claudia Pföhler, Jens Ulrich, Alexander Kreuter, Christiane Pfeiffer, Peter Mohr, Ralf Gutzmer, Friedegund Meier, Edgar Dippel, Michael Weichenthal, Lisa Zimmer, Elisabeth Livingstone, Jürgen C. Becker, Georg Lodde, Antje Sucker, Klaus Griewank, Susanne Horn, Eva Hadaschik, Alexander Roesch, Dirk Schadendorf, Daniel Robert Engel, Selma Ugurel
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPD-1-based immune checkpoint blockade (ICB) is a highly effective therapy in metastatic melanoma. However, 40-60% of patients are primarily resistant, with valid predictive biomarkers currently missing. This study investigated the digitally
Externí odkaz:
https://doaj.org/article/967680da967d4d1da0a6265a5de347ab
Autor:
Jan-Malte Placke, Josefine Rawitzer, Henning Reis, Jassin Rashidi-Alavijeh, Elisabeth Livingstone, Selma Ugurel, Eva Hadaschik, Klaus Griewank, Kurt Werner Schmid, Dirk Schadendorf, Alexander Roesch, Lisa Zimmer
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundGastritis induced by checkpoint inhibitors (CPI) is a rare but severe drug-related side effect. The reference standard for confirming CPI-associated gastritis (CPI-assGastritis) is histopathological assessment; however, the histopathologica
Externí odkaz:
https://doaj.org/article/6a873420be894074b315ac7dc5fca2fc
Autor:
Philipp Jansen, Hansgeorg Müller, Georg C. Lodde, Anne Zaremba, Inga Möller, Antje Sucker, Annette Paschen, Stefan Esser, Jörg Schaller, Matthias Gunzer, Fabian Standl, Sebastian Bauer, Dirk Schadendorf, Thomas Mentzel, Eva Hadaschik, Klaus G. Griewank
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Cutaneous vascular tumors consist of a heterogeneous group of benign proliferations, including a range of hemangiomas and vascular malformations, as well as heterogeneous groups of both borderline and malignant neoplasms such as Kaposi’s sarcoma an
Externí odkaz:
https://doaj.org/article/34acb5afcadb41cab7bece0492221111