Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eva, Erlandsson"'
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Autor:
Fatemeh Safi, Parashar Dhapola, Sarah Warsi, Mikael Sommarin, Eva Erlandsson, Jonas Ungerbäck, Rebecca Warfvinge, Ewa Sitnicka, David Bryder, Charlotta Böiers, Ram Krishna Thakur, Göran Karlsson
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113357- (2023)
Externí odkaz:
https://doaj.org/article/afa99b9a000946b79b1053681bd6ceed
Autor:
Parashar Dhapola, Johan Rodhe, Rasmus Olofzon, Thomas Bonald, Eva Erlandsson, Shamit Soneji, Göran Karlsson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
As the scale of single-cell genomics experiments grows into the millions, the computational requirements to process this data are beyond the reach of many. Here the authors present Scarf, a modularly designed Python package that makes the analysis wo
Externí odkaz:
https://doaj.org/article/60f7efb619a7412992aebe738a7a79f6
In vitro clonal multilineage differentiation of distinct murine hematopoietic progenitor populations
Autor:
Fatemeh Safi, Parashar Dhapola, Eva Erlandsson, Linda Geironson Ulfsson, Ariana S. Calderón, Charlotta Böiers, Göran Karlsson
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101965- (2023)
Summary: Here we describe an in vitro co-culture system that can differentiate hematopoietic progenitor populations to all major hematopoietic lineages at clonal level. We present both a sensitive single-cell switch-culture system as well as a less l
Externí odkaz:
https://doaj.org/article/5c57f55d5800494682503c01d97127a2
Autor:
Jenny Mattsson, Ludvig Ekdahl, Fredrik Junghus, Ram Ajore, Eva Erlandsson, Abhishek Niroula, Maroulio Pertesi, Björn Frendéus, Ingrid Teige, Björn Nilsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Efficient deconvolution of antibody targets is needed for phenotype-based discovery. Here, the authors investigate a deconvolution approach based on pooled CRISPR Cas9 to achieve 97% deconvolution success rate.
Externí odkaz:
https://doaj.org/article/6e2a5135b9de48a8b79f53b16495e80f
Autor:
Talia Velasco-Hernandez, Shamit Soneji, Isabel Hidalgo, Eva Erlandsson, Jörg Cammenga, David Bryder
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 112-121 (2019)
Summary: Relapse of acute myeloid leukemia (AML) remains a significant clinical challenge due to limited therapeutic options and poor prognosis. Leukemic stem cells (LSCs) are the cellular units responsible for relapse in AML, and strategies that tar
Externí odkaz:
https://doaj.org/article/9b5de8aba92f4d12b38fcb0636e34c0c
Autor:
Martin Wahlestedt, Eva Erlandsson, Trine Kristiansen, Rong Lu, Cord Brakebusch, Irving L. Weissman, Joan Yuan, Javier Martin-Gonzalez, David Bryder
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Age-associated decline in tissue function has been linked to alterations in adult stem cells, with implications for organ homeostasis and cellular therapy. Here, the authors study the heterogeneity of ageing mouse haematopoietic stem cells (HSCs) and
Externí odkaz:
https://doaj.org/article/45468cb969c947199083e10e2b6af32d
Autor:
Petter Säwen, Mohamed Eldeeb, Eva Erlandsson, Trine A Kristiansen, Cecilia Laterza, Zaal Kokaia, Göran Karlsson, Joan Yuan, Shamit Soneji, Pankaj K Mandal, Derrick J Rossi, David Bryder
Publikováno v:
eLife, Vol 7 (2018)
A hallmark of adult hematopoiesis is the continuous replacement of blood cells with limited lifespans. While active hematopoietic stem cell (HSC) contribution to multilineage hematopoiesis is the foundation of clinical HSC transplantation, recent rep
Externí odkaz:
https://doaj.org/article/c65d59c4c6b34c25b69c383fd329544e
Autor:
Björn Nilsson, Björn Frendéus, Eva Erlandsson, Maroulio Pertesi, Ingrid Teige, Abhishek Niroula, Jenny Mattsson, Ludvig Ekdahl, Fredrik Junghus, Ram Ajore
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature Communications
Therapeutic antibodies are transforming the treatment of cancer and autoimmune diseases. Today, a key challenge is finding antibodies against new targets. Phenotypic discovery promises to achieve this by enabling discovery of antibodies with therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbe886e3f1eab630bb3eed30348af9b
https://doaj.org/article/6e2a5135b9de48a8b79f53b16495e80f
https://doaj.org/article/6e2a5135b9de48a8b79f53b16495e80f
Autor:
Parashar Dhapola, Johan Rodhe, Rasmus Olofzon, Thomas Bonald, Eva Erlandsson, Shamit Soneji, Göran Karlsson
Publikováno v:
Nature communications. 13(1)
As the scale of single-cell genomics experiments grows into the millions, the computational requirements to process this data are beyond the reach of many. Herein we present Scarf, a modularly designed Python package that seamlessly interoperates wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da504ed086c1a3a29848c1efb6f71a2c
https://pubmed.ncbi.nlm.nih.gov/35941103
https://pubmed.ncbi.nlm.nih.gov/35941103
Autor:
Shamit Soneji, David Bryder, Talia Velasco-Hernandez, Eva Erlandsson, Isabel Hidalgo, Jörg Cammenga
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 112-121 (2019)
Stem Cell Reports
Stem Cell Reports
Summary Relapse of acute myeloid leukemia (AML) remains a significant clinical challenge due to limited therapeutic options and poor prognosis. Leukemic stem cells (LSCs) are the cellular units responsible for relapse in AML, and strategies that targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded7804ab0b72b6dab612df088703984
http://www.sciencedirect.com/science/article/pii/S2213671118304922
http://www.sciencedirect.com/science/article/pii/S2213671118304922