Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Eva, Brcakova"'
Autor:
Cibickova, Lubica a, ⁎, Radomir, Hyspler b, Stanislav, Micuda c, Norbert, Cibicek d, Helena, Zivna e, Daniel, Jun f, Alena, Ticha b, Eva, Brcakova c, Vladimir, Palicka d
Publikováno v:
In Steroids 2009 74(1):13-19
Publikováno v:
Open Journal of Endocrine and Metabolic Diseases. :46-51
Objective: We studied the influence of bile duct obstruction (BDO) after 28 days on bone metabolism status and their modification by resveratrol in male Wistar rats. Methods: The rats were divided into 3 groups: Sham group with laparotomy and vehicul
Autor:
Martina Slanarova, Zbynek Strasky, Lenka Vecerova, Eva Brcakova, Stanislav Micuda, Jana Rathouska, Petr Nachtigal
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 19:115-126
Aim: Transforming growth factor-beta (TGF-β) plays important role in atherogenesis via TGF-β receptors and Smad proteins, which determine its signaling activity. In this study, we hypothesized, whether non-lipid related effects of atorvastatin, aff
Autor:
Eva Brcakova, Gabriela Kolouchova, Leos Fuksa, Petra Hirsova, Hana Lastuvkova, Jolana Cermanova, Jaroslav Mokry, Petr Nachtigal, Stanislav Micuda
Publikováno v:
Life Sciences. 89:717-724
Aims To evaluate iron biochemistry and contributing liver mechanisms during obstructive cholestasis and pravastatin treatment in rats. Main methods A rat model of cholestasis induced by bile duct ligation (BDL) was used for the study. The detection o
Autor:
Jolana Cermanova, Pavel Tomsik, Halka Lotková, Ludek Sispera, Martina Slanarova, Radek Hyspler, Stanislav Micuda, Eva Brcakova, Leos Fuksa, Gabriela Kolouchova, Petra Hirsova
Publikováno v:
Journal of Gastroenterology and Hepatology. 26:1544-1551
Background and Aim: The administration of pravastatin to patients with cholestatic liver disease has suggested the potential of the drug with regard to reducing raised plasma cholesterol and bile acid levels. Information about the mechanisms associat
Autor:
Lenka Bruckova, Tomáš Soukup, Eva Brcakova, Lenka Kucerova, Stanislav Micuda, Jaroslav Mokry, Jana Pavelkova, Jiri Moos, Benjamin Visek, Karel Rezabek, Martina Moosova
Publikováno v:
Journal of Assisted Reproduction and Genetics. 28:939-950
The aim of this study was to develop and optimize a strategy for long-term cultivation of luteinizing human granulosa cells (GCs).GCs were cultivated in DMEM/F12 medium supplemented with 2% fetal calf serum. In vitro proliferation of GCs was supporte
Autor:
Zuzana Červinková, Tomáš Roušar, Eva Brcakova, Lukás Kohoutek, Gabriela Kolouchova, Stanislav Micuda, Otto Kucera, Halka Lotková, Pavla Staňková
Publikováno v:
General Physiology and Biophysics. 30:66-74
Antiinflammatory effect of statins mediated by the reduction of cytokine IL-6 in hepatocytes have been reported. Contrary to beneficial effect, statins can increase susceptibility to mitochondrial dysfunction. Extrahepatic biliary obstruction is asso
Autor:
Eva Brcakova, Lenka Vecerova, Zbynek Strasky, Martina Slanarova, Zdenka Kudlackova, Jana Rathouska, Petr Nachtigal, Stanislav Micuda, Ctirad Andrys
Publikováno v:
Circulation Journal. 75:1747-1755
Background: The aim of the study was to evaluate whether cholesterol-rich diet affects transforming growth factor-β-RIII (endoglin) levels in blood and 2 endoglin-related pathways in the aorta of ApoE/LDLR double knockout mice. Methods and Results:
Methotrexate released in vitro from bone cement inhibits human stem cell proliferation in S/G2 phase
Autor:
Gabriela Kolouchova, Jaroslav Mokry, Stanislav Micuda, Eva Brcakova, Jolana Cermanova, Milos Hroch, Karel Urban, Tomáš Soukup, Egon Prochazka, Leos Fuksa
Publikováno v:
International Orthopaedics. 34:137-142
Methotrexate (MTX) released from bone cement showed a useful local effect in animal models of bone tumours. However, local toxic reactions such as impaired wound healing were observed in areas surrounding the MTX-loaded implant. Therefore, we hypothe
Autor:
Jaroslav Mokry, Frantisek Staud, Norbert Cibicek, Jolana Cermanova, Jan Österreicher, Leos Fuksa, Eva Brcakova, Stanislav Micuda, Jirina Martinkova
Publikováno v:
Journal of Gastroenterology and Hepatology. 23:e225-e230
Background and Aim: The present study was aimed to evaluate the hepatic zonation of multidrug resistance-associated protein 2 (mrp2), an important drug transporter, and its potential changes during the induction of its expression by known inducer, de