Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Euzenir Nunes, Sarno"'
Autor:
Clarissa Neves Spitz, Izabela Jardim R. Pitta, Ligia Andrade, Larissa Bittencourt de Carvalho, Diogo Matheus Terrana de Carvalho, Felipe da Rocha Schmidt, Ana Caroline Siquara de Sousa, Silvana Machado Mendonça, Euzenir Nunes Sarno, Anna Maria Sales, Roberta Olmo Pinheiro, Marcia Rodrigues Jardim
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Hansen’s disease, or leprosy, is a disease characterized by dermatological and neurological disorders. A neural form also exists, in which peripheral neuropathy occurs in the absence of skin lesions. However, cases of leprosy that involve the centr
Externí odkaz:
https://doaj.org/article/bd22034c41c842558aa2fc541a0769d1
Autor:
Izabela Jardim R. Pitta, Debora Bartzen Moraes Angst, Roberta Olmo Pinheiro, Joyce Soares da Silva Vieira, Clarissa Neves Spitz, Ligia Rocha Andrade, Larissa Bittencourt Carvalho, Mariana Andrea Hacker, Euzenir Nunes Sarno, Marcia Rodrigues Jardim
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPure Neural Leprosy (PNL) is a form of this long time known disease that affects only the peripheral nervous system. Since it is a rare form of the disease, its pathophisiology is still poorly understood.ObjectiveDescribe the cytokines pr
Externí odkaz:
https://doaj.org/article/3bbedcce9e6b46d5b5127ff73f947148
Autor:
Patricia Sola Penna, Sergio Augusto Lopes De Souza, Paulo Gustavo Limeira Nobre De Lacerda, Izabela Jardim Rodrigues Pitta, Clarissa Neves Spitz, Anna Maria Sales, Flavio Alves Lara, Ana Caroline Siquara De Souza, Euzenir Nunes Sarno, Roberta Olmo Pinheiro, Marcia Rodrigues Jardim
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 6, p e0011383 (2023)
BackgroundLeprosy is caused by multiple interactions between Mycobacterium leprae (M. leprae) and the host's peripheral nerve cells. M. leprae primarily invades Schwann cells, causing nerve damage and consequent development of disabilities. Despite i
Externí odkaz:
https://doaj.org/article/c66ffc5831bd4d8cb27b3816388ef3c5
Autor:
Clarissa Neves Spitz, Izabela Jardim Rodrigues Pitta, Ligia Rocha Andrade, Anna Maria Sales, Euzenir Nunes Sarno, Nivaldo Ribeiro Villela, Roberta Olmo Pinheiro, Marcia Rodrigues Jardim
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
One of the main manifestations of leprosy is peripheral nerve impairment. Early diagnosis and treatment are important to reduce the impact of neurological impairment, which can cause deformities and physical disabilities. Leprosy neuropathy can be ac
Externí odkaz:
https://doaj.org/article/190c811dd02c4c4f9ab35b5fc56b1c0d
Autor:
Eloisa Helena Medeiros Cunha, Pedro Henrique Ferreira Marçal, Rafael Silva Gama, Lorena Bruna Pereira de Oliveira, Roberta Olmo Pinheiro, Euzenir Nunes Sarno, Joaquim Pedro Brito-de-Sousa, Márcio Luís Moreira de Souza, Jessica Kathleen Fairley, Thaisa Netto Souza Valente, Cibele Velloso-Rodrigues, Olindo Assis Martins-Filho, Dirce Ribeiro de Oliveira, Lucia Alves de Oliveira Fraga
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe aim of the present study was to investigate the association between the single nucleotide polymorphism (SNP) rs1927914 A/G in TLR4 gene and the immunological profile of household contacts (HHC) of leprosy patients. Leprosy classificat
Externí odkaz:
https://doaj.org/article/bd372c38fa88494ab209f968a1e168f3
Autor:
Rhana Berto da Silva Prata, Mayara Abud Mendes, Vinicius Cardoso Soares, Jaqueline França-Costa, Anna Maria Sales, Nádia Cristina Duppré, Valéria de Matos Borges, Tatiana Pereira da Silva, Patricia Torres Bozza, Marcelo Torres Bozza, Euzenir Nunes Sarno, Milton Ozório Moraes, Gilberto Marcelo Sperandio da Silva, Roberta Olmo Pinheiro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Leprosy household contacts are generally more prone to develop the disease compared to the general population. Previous studies have demonstrated that genes related to the alternative activation (M2) profile in macrophages are associated wit
Externí odkaz:
https://doaj.org/article/5bb55f4a9acf46eaacdfd1f0bbc6cdd2
Autor:
Louise Mara Giesel, Yara Hahr Marques Hökerberg, Izabela Jardim Rodrigues Pitta, Lígia Rocha Andrade, Debora Bartzen Moraes, José Augusto da Costa Nery, Euzenir Nunes Sarno, Marcia Rodrigues Jardim
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Diagnosing neuritis in leprosy patients with neuropathic pain or chronic neuropathy remains challenging since no specific laboratory or neurophysiological marker is available. Methods In a cross-sectional study developed at a lepr
Externí odkaz:
https://doaj.org/article/78c4bd174ac34f89b1e4e036db8243d9
Autor:
Euzenir Nunes Sarno
Publikováno v:
Revista Brasileira de Educação Médica, Vol 4, Iss 1, Pp 2-4 (2022)
Externí odkaz:
https://doaj.org/article/5fc6b9dae3574c56bca4536628939b58
Autor:
Helen Ferreira, Thyago Leal-Calvo, Mayara Abud Mendes, Charlotte Avanzi, Philippe Busso, Andrej Benjak, Anna Maria Sales, Cássio Porto Ferreira, Márcia de Berrêdo-Pinho, Stewart Thomas Cole, Euzenir Nunes Sarno, Milton Ozório Moraes, Roberta Olmo Pinheiro
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Multidrug therapy (MDT) has been successfully used in the treatment of leprosy. However, although patients are cured after the completion of MDT, leprosy reactions, permanent disability, and occasional relapse/reinfection are frequently observed in p
Externí odkaz:
https://doaj.org/article/322b90006fe1492baddc5a9e4e25637a
Autor:
Mariana Andrea Hacker, Anna Maria Sales, Nádia Cristina Duppre, Euzenir Nunes Sarno, Milton Ozório Moraes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Reduction in incidence has been associated with the introduction of novel approaches, like chemo/immune-prophylaxis. Incidence determined through follow-up cohort studies can evaluate the implementation of these innovative policies towards c
Externí odkaz:
https://doaj.org/article/4f52d0bafff44e62bc5db82505002b7f