Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Euzébio Guimaraes Barbosa"'
Autor:
Luana Carvalho de Oliveira, Danielle Lima Bezerra de Menezes, Valéria Costa da Silva, Estela Mariana Guimarães Lourenço, Paulo Henrique Santana Miranda, Márcia de Jesus Amazonas da Silva, Emerson Silva Lima, Valdir Florêncio da Veiga Júnior, Ricardo Neves Marreto, Attilio Converti, Euzébio Guimaraes Barbosa, Ádley Antonini Neves de Lima
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9882 (2021)
α,β-amyrenone (ABAME) is a triterpene derivative with many biological activities; however, its potential pharmacological use is hindered by its low solubility in water. In this context, the present work aimed to develop inclusion complexes (ICs) of
Externí odkaz:
https://doaj.org/article/e51bdb72055a4dba9d3d68f2dbda6475
Autor:
Jéssika de Oliveira Viana, Eden Silva e Souza, Nicolau Sbaraini, Marilene Henning Vainstein, Joilly Nilce Santana Gomes, Ricardo Olímpio de Moura, Euzébio Guimarães Barbosa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The concept of “one target, one drug, one disease” is not always true, as compounds with previously described therapeutic applications can be useful to treat other maladies. For example, acridine derivatives have several potential therap
Externí odkaz:
https://doaj.org/article/bbc3da205576417d97c63b4d8e1ccceb
Autor:
Priscilla Suene de Santana Nogueira Silverio, Jéssika de Oliveira Viana, Euzébio Guimarães Barbosa
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 59 (2023)
Abstract Quantitative Structure-Activity Relationship (QSAR) is a computer-aided technology in the field of medicinal chemistry that seeks to clarify the relationships between molecular structures and their biological activities. Such technologies al
Externí odkaz:
https://doaj.org/article/d9f68ffb89ad4dfba7d81306acde55cb
Autor:
Sergio Ortiz, François Peurois, Euzébio Guimarães Barbosa, Mohamed Selkti, Pascale Lemoine, Jacqueline Cherfils, Raphaël Grougnet, Sabrina Boutefnouchet
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 6, Iss , Pp 100090- (2022)
The GDP/GTP conformational change of Arf GTPase proteins by different guanine exchange factor GEFs proteins (Big1Sec7, ARNOSec7, Brag1Sec7, etc.), modulates important eukaryotes cell functions, such as secretion, endocytosis, phagocytosis, cytokinesi
Externí odkaz:
https://doaj.org/article/49fd9101b00a4736b8b7e124c4f4cef8
Autor:
Estela Mariana Guimarães Lourenço, Juliana Fortes Di Iório, Fernanda da Silva, Felipe Leonardo Bley Fialho, Melquisedeque Mateus Monteiro, Adilson Beatriz, Renata Trentin Perdomo, Euzébio Guimarães Barbosa, Jean Pierre Oses, Carla Cardozo Pinto de Arruda, Wagner Alves de Souza Júdice, Jamal Rafique, Dênis Pires de Lima
Publikováno v:
Microorganisms, Vol 11, Iss 1, p 225 (2023)
Leishmaniasis is a neglected tropical disease, affecting more than 350 million people globally. However, there is currently no vaccine available against human leishmaniasis, and current treatment is hampered by high cost, side-effects, and painful ad
Externí odkaz:
https://doaj.org/article/48865976a47f4ad58151c668d88f1786
Autor:
Eden Silva e Souza, Vanessa de Abreu Barcellos, Nicolau Sbaraini, Júlia Catarina Vieira Reuwsaat, Rafael de Oliveira Schneider, Adriana Corrêa da Silva, Ane Wichine Acosta Garcia, Gilsane Lino von Poser, Euzébio Guimarães Barbosa, João Paulo Matos Santos Lima, Marilene Henning Vainstein
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Cryptococcosis is a fungal infection caused mainly by the pathogenic yeasts Cryptococcus neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules that are then deposited in the lungs. If not properly treated, cryp
Externí odkaz:
https://doaj.org/article/8c721fbdf7f94f43b8e2cf8733fc070a
Autor:
Catarina G. Pereira, Carolina Borsoi Moraes, Caio H. Franco, Clarissa Feltrin, Raphaël Grougnet, Euzébio Guimarães Barbosa, Michele Panciera, Carlos Roque D. Correia, Maria João Rodrigues, Luísa Custódio
Publikováno v:
Plants, Vol 10, Iss 11, p 2235 (2021)
Marine halophytes are an outstanding reservoir of natural products and several species have anti-infectious traditional uses. However, reports about their potential use against neglected tropical ailments, such as Chagas disease, are scarce. This wor
Externí odkaz:
https://doaj.org/article/2a6d57c8fffe49b39b1b3c0696afffa5
Autor:
Thalita Sévia Soares de Almeida Magalhães, Pollyana Cristina de Oliveira Macedo, Stephany Yumi Kawashima Pacheco, Sofia Santos da Silva, Euzébio Guimarães Barbosa, Rayanne Rocha Pereira, Roseane Maria Ribeiro Costa, José Otávio Carréra Silva Junior, Marília Andreza da Silva Ferreira, José Cezário de Almeida, Pedro José Rolim Neto, Attilio Converti, Ádley Antonini Neves de Lima
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 942 (2020)
The development of inclusion complexes is used to encapsulate nonpolar compounds and improve their physicochemical characteristics. This study aims to develop complexes made up of Euterpe oleracea Mart oil (EOO) and β-cyclodextrin (β-CD) or hydroxy
Externí odkaz:
https://doaj.org/article/eb18ad338ba8418aa7af0c69bb75c688
Autor:
Jonas Gabriel de Oliveira Pinheiro, Emanuella de Aragão Tavares, Sofia Santos da Silva, Juliana Félix Silva, Yasmim Maria Barbosa Gomes de Carvalho, Magda Rhayanny Assunção Ferreira, Adriano Antunes de Souza Araújo, Euzébio Guimarães Barbosa, Matheus de Freitas Fernandes Pedrosa, Luiz Alberto Lira Soares, Eduardo Pereira de Azevedo, Valdir Florêncio da Veiga Júnior, Ádley Antonini Neves de Lima
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2388 (2017)
Complexation with cyclodextrins (CDs) is a technique that has been extensively used to increase the aqueous solubility of oils and improve their stability. In addition, this technique has been used to convert oils into solid materials. This work aims
Externí odkaz:
https://doaj.org/article/7717e690839541199dc88976ced0f32a
Autor:
Elen Diana Dantas, Fabia Julliana Jorge de Souza, William Nascimento Litaiff Nogueira, Cláudia Cândida Silva, Pedro Henrique Antunes de Azevedo, Cícero Flávio Soares Aragão, Patricia Danielle Oliveira de Almeida, Mariana Filomena do Carmo Cardoso, Fernando de Carvalho da Silva, Eduardo Pereira de Azevedo, Euzébio Guimarães Barbosa, Emerson Silva Lima, Vitor Francisco Ferreira, Ádley Antonini Neves de Lima
Publikováno v:
Molecules, Vol 22, Iss 10, p 1631 (2017)
Chagas disease is an endemic parasitic infection that occurs in 21 Latin American countries. New therapies for this disease are urgently needed, as the only two drugs available (nifurtimox and benznidazol) have high toxicity and variable efficacy in
Externí odkaz:
https://doaj.org/article/bf4afbb8fc744ed4baf32d030ed766e1