Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Euy Sung, Moon"'
Autor:
Tilman Läppchen, Adrianna Bilinska, Eirinaios Pilatis, Elena Menéndez, Surachet Imlimthan, Euy Sung Moon, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
Molecules, Vol 29, Iss 13, p 3093 (2024)
Background: FAP radiopharmaceuticals show promise for cancer diagnosis; however, their limited tumor residency hinders treatment. This study compared two FAPi derivatives, DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2, labeled with gallium-68 and lutetium-177,
Externí odkaz:
https://doaj.org/article/285d4217cb994469b1b11d23d67b90fa
Autor:
Rahul Viswanathan, Sanjana Ballal, Madhav P. Yadav, Frank Roesch, Parvind Sheokand, Swayamjeet Satapathy, Madhavi Tripathi, Shipra Agarwal, Euy Sung Moon, Chandrasekhar Bal
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 275 (2024)
Neuroendocrine tumors (NETs) are slow-growing tumors that express high levels of somatostatin receptors (SSTRs). Recent studies have shown the superiority of radiolabeled SSTR antagonists in theranostics compared to agonists. In this prospective stud
Externí odkaz:
https://doaj.org/article/fa1451c9d0304faeacd69e299083da0f
Autor:
Sanjana Ballal, Madhav P. Yadav, Frank Roesch, Nicky Wakade, Shobhana Raju, Parvind Sheokand, Prashant Mishra, Euy Sung Moon, Madhavi Tripathi, Marcel Martin, Chandrasekhar Bal
Publikováno v:
Pharmaceuticals, Vol 16, Iss 4, p 521 (2023)
This study aimed to compare the diagnostic performance of [68Ga]Ga-DOTA.SA.FAPi with that of [18F]F-FDG PET/CT in detecting primary and metastatic lesions of breast cancer. [18F]F-FDG and [68Ga]Ga-DOTA.SA.FAPi PET/CT scans of histologically proven br
Externí odkaz:
https://doaj.org/article/859dc10bbab44138b3eb8ab05751a9e8
Autor:
Jean-Philippe Sinnes, Ulrike Bauder-Wüst, Martin Schäfer, Euy Sung Moon, Klaus Kopka, Frank Rösch
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract Background The AAZTA chelator and in particular its bifunctional derivative AAZTA5 was recently investigated to demonstrate unique capabilities to complex diagnostic and therapeutic trivalent radiometals under mild conditions. This study pre
Externí odkaz:
https://doaj.org/article/d1a2d3b0fd9c4b479ae97266b454021c
Autor:
Michael Hofstetter, Euy Sung Moon, Fabio D’Angelo, Lucien Geissbühler, Ian Alberts, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-19 (2020)
Abstract Background Gastrin Releasing Peptide receptor (GRPr)-based radioligands have shown great promise for diagnostic imaging of GRPr-positive cancers, such as prostate and breast. The present study aims at developing and evaluating a versatile GR
Externí odkaz:
https://doaj.org/article/4a0fe7b14d8f475ab34e7db297ebd9f2
Autor:
Euy Sung Moon, Filipe Elvas, Gwendolyn Vliegen, Stef De Lombaerde, Christel Vangestel, Sven De Bruycker, An Bracke, Elisabeth Eppard, Lukas Greifenstein, Benedikt Klasen, Vasko Kramer, Steven Staelens, Ingrid De Meester, Pieter Van der Veken, Frank Rösch
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-20 (2020)
Abstract Background Fibroblast activation protein (FAP) is a proline selective serine protease that is overexpressed in tumor stroma and in lesions of many other diseases that are characterized by tissue remodeling. In 2014, a most potent FAP-inhibit
Externí odkaz:
https://doaj.org/article/6eef6de76ec3424eabc82ef799f24e24
Autor:
Berthold A. Nock, Panagiotis Kanellopoulos, Euy Sung Moon, Maritina Rouchota, George Loudos, Sanjana Ballal, Madhav P. Yadav, Chandrasekhar Bal, Prashant Mishra, Parvind Sheokand, Frank Roesch, Theodosia Maina
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 776 (2023)
Aiming to expand the application of the SST2R-antagonist LM4 (DPhe-c[DCys-4Pal-DAph(Cbm)-Lys-Thr-Cys]-DTyr-NH2) beyond [68Ga]Ga-DATA5m-LM4 PET/CT (DATA5m, (6-pentanoic acid)-6-(amino)methy-1,4-diazepinetriacetate), we now introduce AAZTA5-LM4 (AAZTA5
Externí odkaz:
https://doaj.org/article/2f0690fde7c64c7fa0a01549ebc2a9b7
Autor:
Lukas Greifenstein, Carsten S. Kramer, Euy Sung Moon, Frank Rösch, Andre Klega, Christian Landvogt, Corinna Müller, Richard P. Baum
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 1000 (2022)
Radiolabeled FAPI (fibroblast activation protein inhibitors) recently gained attention as widely applicable imaging and potential therapeutic compounds targeting CAF (cancer-associated fibroblasts) or DAF (disease-associated fibroblasts in benign dis
Externí odkaz:
https://doaj.org/article/8aa0836d946a4b78b8929321a35eeee3
Autor:
Guangfa Bao, Huimin Zhou, Sijuan Zou, Lixing Chen, Buchuan Zhang, Ziqiang Wang, Euy Sung Moon, Jun Zhao, Frank Roesch, Xiaohua Zhu
Publikováno v:
Molecular Pharmaceutics. 20:2443-2451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a25d3ade7bbb1f488937f96458d9bf
https://doi.org/10.1021/acs.molpharmaceut.2c01051
https://doi.org/10.1021/acs.molpharmaceut.2c01051
Autor:
Sanjana Ballal, Madhav Prasad Yadav, Euy Sung Moon, Vasko S Kramer, Frank Roesch, Samta Kumari, Chandrasekhar Bal
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1212 (2021)
Recently, great interest has been gained regarding fibroblast activation protein (FAP) as an excellent target for theranostics. Several FAP inhibitor molecules such as [68Ga]Ga-labelled FAPI-02, 04, 46, and DOTA.SA.FAPi have been introduced and are h
Externí odkaz:
https://doaj.org/article/54f75134215f4391981c9021e5e3ac07