Výsledky vyhledávání - "Eustacia Zellmer"

Canine DLA-79 gene: an improved typing method, identification of new alleles and its role in graft rejection and graft-versus-host disease

Autor: Rainer Storb, Dan Geraghty, Beverly Torok-Storb, Gopalakrishnan M. Venkataraman, Barry E. Storer, Eustacia Zellmer, Jenifer Fox, Scott S. Graves

Publikováno v: Tissue Antigens. 81:204-211

Developing a preclinical canine model that predicts outcomes for hematopoietic cell transplantation in humans requires a model that mimics the degree of matching between human donor and recipient major histocompatibility complex (MHC) genes. The poly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1da16b07812e9d607c55a5d7fb55cf9
https://doi.org/10.1111/tan.12094

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Principles of Peripheral Blood Mononuclear Cell Apheresis in a Preclinical Canine Model of Hematopoietic Cell Transplantation

Autor: Marilena Lupu, R Storb, Ted Gooley, Scott S. Graves, Eustacia Zellmer

Publikováno v: Journal of Veterinary Internal Medicine. 22:74-82

Background: Preclinical studies of peripheral blood mononuclear cell (PBMC) transplantation conducted in a well-established canine hematopoietic cell transplantation (HCT) model have been successfully translated to human patients over the past 5 deca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dac26956dea1a775203ec8a846150bc
https://doi.org/10.1111/j.1939-1676.2007.0016.x

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Failure of Donor Lymphocyte Infusion to Prevent Graft Rejection in Dogs Given DLA-Identical Marrow after 1 Gy of Total Body Irradiation

Autor: Mohamed L. Sorror, Brenda M. Sandmaier, Rainer Storb, Frédéric Baron, Barry E. Storer, Eustacia Zellmer

Publikováno v: Biology of Blood and Marrow Transplantation. 12:813-817

We investigated in a preclinical canine model of hematopoietic cell transplantation (HCT) whether preemptive donor lymphocyte infusion (DLI) given 1 month after HCT could prevent late graft rejection that was the rule in historical dogs given subopti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d3ea1fd6628bceb476953838567c11
https://doi.org/10.1016/j.bbmt.2006.05.001

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Use of multigeneration-family molecular dog leukocyte antigen typing to select a hematopoietic cell transplant donor for a dog with T-cell lymphoma

Autor: Edmund W. Sullivan, Peter F Moore, Eustacia Zellmer, Rainer Storb, Theresa E. Westfall, B. J. Weigler, Marie Térèse Little, Marilena Lupu, Christian S. Kuhr, Patrice A. Stroup

Publikováno v: Journal of the American Veterinary Medical Association. 228:728-732

Case Description—A 7-year-old Golden Retriever was examined because of anorexia, lethargy, vomiting, and gradual weight loss. Clinical Findings—Splenomegaly, pancytopenia, high serum calcium concentration, and high alkaline phosphatase activity w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf25ee5f881e4ab5fe3d45c2dbe3e590
https://doi.org/10.2460/javma.228.5.728

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Hematopoietic stem cell transplantation does not restore dystrophin expression in Duchenne muscular dystrophy dogs

Autor: Marie Térèse Little, Serina Gisburne, Stephen J. Tapscott, Barry J. Cooper, Christian S. Kuhr, Zejing Wang, Chiara Dell'Agnola, Joe N. Kornegay, Richard S. Lee, George E. Sale, Stephen D. Hauschka, Eustacia Zellmer, Rainer Storb, Janet R. Bogan, Ted Gooley

Publikováno v: Blood. 104:4311-4318

Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene on the X-chromosome that result in skeletal and cardiac muscle damage and premature death. Studies in mice, including the mdx mouse model of DMD, have demonstrated that c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2127ccf97a2e37033adbef95e22e0d7c
https://doi.org/10.1182/blood-2004-06-2247

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FTY720 does not abrogate acute graft-versus-host disease in the dog leukocyte antigennonidentical unrelated canine model1

Autor: Richard S. Lee, Rainer Storb, Eustacia Zellmer, William J. Hogan, Christian S. Kuhr, Marie Térèse Little, George E. Sale

Publikováno v: Transplantation. 76:1155-1158

Background Acute graft-versus-host disease (GVHD) remains a significant impediment to successful hematopoietic stem-cell transplantation (HSCT). Here, we examined the effectiveness of 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol hydrochloride (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1eb564532e0c9b5b8342d82a7c98886
https://doi.org/10.1097/01.tp.0000083891.14089.b8

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RDP58 Does Not Prevent Graft-Versus-Host Disease After Dog Leukocyte Antigen–Nonidentical Canine Hematopoietic Cell Transplantation

Autor: Marilena Lupu, Marie-Térèse Little, Rainer Storb, Christian S. Kuhr, Eustacia Zellmer, George E. Sale

Publikováno v: Transplantation. 81:1460-1462

Graft-versus-host disease (GVHD) remains a cause of substantial morbidity for patients undergoing allogeneic hematopoietic cell transplantation (HCT). The present study was undertaken to investigate the effectiveness of RDP58, a peptide derived from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfafd1d9edc5a814f34db60dacd040d
https://doi.org/10.1097/01.tp.0000203323.82681.7d

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The Homeodomain Protein Arix Interacts Synergistically with Cyclic AMP to Regulate Expression of Neurotransmitter Biosynthetic Genes

Autor: Douglas J. Swanson, Elaine J. Lewis, Eustacia Zellmer

Publikováno v: Journal of Biological Chemistry. 272:27382-27392

Transcription of the neurotransmitter biosynthetic genes tyrosine hydroxylase and dopamine beta-hydroxylase (DBH) is regulated by cell type-specific transcription factors, including the homeoprotein Arix, and second messengers, including cyclic AMP.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89db9b54ff06abe32a510692aa7c4ddf
https://doi.org/10.1074/jbc.272.43.27382

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Delaying DLA-Haploidentical Hematopoietic Cell Transplantation After Total Body Irradiation

Autor: Reza Forough, George E. Sale, Scott S. Graves, Barry E. Storer, Eustacia Zellmer, Brenda M. Sandmaier, Laura J. Peterson, George E. Georges, Marcello Rotta, Yunchuan Ding, Rainer Storb, Christian S. Kuhr

Exposure to accidental or deliberate radiation poses a threat to public health, proving lethal at higher doses in large part because of deleterious effects on marrow. In those cases, allogeneic hematopoietic cell transplantation (HCT) might be requir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c59150f085fac456e168e2da8d41cd6
https://europepmc.org/articles/PMC2757126/

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Intussusception in canine recipients of hematopoietic cell grafts and surgical correction

Autor: Murad Y, Yunusov, Fabio, Kerbauy, Kraig, Abrams, Eustacia, Zellmer, Michele, Spector, Christian S, Kuhr, Billanna, Hwang, Barry, Storer, George E, Georges, Benjamin J, Weigler, Rainer, Storb, Richard A, Nash

Publikováno v: Comparative medicine. 57(3)

Intussusception is a common complication after canine hematopoietic cell transplantation (HCT). The present study was undertaken to evaluate predisposing factors of intussusception and to test whether intussusception can be managed surgically during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::58ddce6fa3532473493f01d2ee553968
https://pubmed.ncbi.nlm.nih.gov/17605344

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