An in vivo model of glioblastoma radiation resistance identifies long noncoding RNAs and targetable kinases.

Autor: Stackhouse CT; Department of Neurosurgery.; Department of Radiation Oncology, and., Anderson JC; Department of Radiation Oncology, and., Yue Z; Informatics Institute, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. Birmingham, Alabama, USA., Nguyen T; Informatics Institute, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. Birmingham, Alabama, USA., Eustace NJ; Department of Radiation Oncology, and., Langford CP; Department of Neurosurgery., Wang J; Informatics Institute, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. Birmingham, Alabama, USA., Rowland JR 4th; Department of Physics, The Ohio State University, Columbus, Ohio, USA., Xing C; Department of Radiation Oncology, and., Mikhail FM; Department of Genetics, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Cui X; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA., Alrefai H; Department of Radiation Oncology, and., Bash RE; Division of Neuropathology, Department of Pathology, and., Lee KJ; Department of Radiation Oncology, and., Yang ES; Department of Radiation Oncology, and., Hjelmeland AB; Department of Cell, Developmental, and Integrative Biology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Miller CR; Division of Neuropathology, Department of Pathology, and., Chen JY; Informatics Institute, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. Birmingham, Alabama, USA., Gillespie GY; Department of Neurosurgery., Willey CD; Department of Radiation Oncology, and.

Publikováno v: JCI insight [JCI Insight] 2022 Aug 22; Vol. 7 (16). Date of Electronic Publication: 2022 Aug 22.

Myristoylated alanine-rich C-kinase substrate effector domain phosphorylation regulates the growth and radiation sensitization of glioblastoma.

Autor: Eustace NJ; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Anderson JC; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Langford CP; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Trummell HQ; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Hicks PH; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Jarboe JS; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL 33136, USA., Mobley JA; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Hjelmeland AB; Department of Cell molecular and Developmental Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Hackney JR; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Pedersen RT; ChemoMetec, DK-3450 Allerod, Denmark., Cosby K; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Gillespie GY; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Bonner JA; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Willey CD; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Publikováno v: International journal of oncology [Int J Oncol] 2019 Jun; Vol. 54 (6), pp. 2039-2053. Date of Electronic Publication: 2019 Mar 29.

MARCKS phosphorylation is modulated by a peptide mimetic of MARCKS effector domain leading to increased radiation sensitivity in lung cancer cell lines.

Autor: Rohrbach TD; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Jones RB; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Hicks PH; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Weaver AN; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Cooper TS; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Eustace NJ; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Yang ES; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Jarboe JS; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Anderson JC; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA., Willey CD; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

Publikováno v: Oncology letters [Oncol Lett] 2017 Mar; Vol. 13 (3), pp. 1216-1222. Date of Electronic Publication: 2016 Dec 29.