Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Eusondia Arnett"'
Autor:
Eusondia Arnett, Susanta Pahari, Chrissy M. Leopold Wager, Elizabeth Hernandez, Jordan R. Bonifacio, Miranda Lumbreras, Charles Renshaw, Maria J. Montoya, Joseph T. Opferman, Larry S. Schlesinger
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115738- (2023)
Tuberculosis (TB) accounts for 1.6 million deaths annually and over 25% of deaths due to antimicrobial resistance. Mycobacterium tuberculosis (M.tb) drives MCL-1 expression (family member of anti-apoptotic BCL-2 proteins) to limit apoptosis and grow
Externí odkaz:
https://doaj.org/article/f64293c1f955435bbace452bda940057
Autor:
Susanta Pahari, Eusondia Arnett, Jan Simper, Abul Azad, Israel Guerrero-Arguero, Chengjin Ye, Hao Zhang, Hong Cai, Yufeng Wang, Zhao Lai, Natalie Jarvis, Miranda Lumbreras, Diego Jose Maselli, Jay Peters, Jordi B. Torrelles, Luis Martinez-Sobrido, Larry S. Schlesinger
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Alveolar macrophages (AMs) are unique lung resident cells that contact airborne pathogens and environmental particulates. The contribution of human AMs (HAMs) to pulmonary diseases remains poorly understood due to the difficulty in accessing
Externí odkaz:
https://doaj.org/article/1606ea0b7b6449dabb3bd799cf4140d6
Autor:
Chrissy M Leopold Wager, Jordan R Bonifacio, Jan Simper, Adrian A Naoun, Eusondia Arnett, Larry S Schlesinger
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011297 (2023)
Macrophages are a first line of defense against pathogens. However, certain invading microbes modify macrophage responses to promote their own survival and growth. Mycobacterium tuberculosis (M.tb) is a human-adapted intracellular pathogen that explo
Externí odkaz:
https://doaj.org/article/86c951c3530c4adb9cc0e3e348070ab8
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The risk of active tuberculosis disease is 15-21 times higher in those coinfected with human immunodeficiency virus-1 (HIV) compared to tuberculosis alone, and tuberculosis is the leading cause of death in HIV+ individuals. Mechanisms driving synergy
Externí odkaz:
https://doaj.org/article/91f0d61f6b0643eda98e796045ae7fca
Autor:
Murugesan V.S. Rajaram, Eusondia Arnett, Abul K. Azad, Evelyn Guirado, Bin Ni, Abigail D. Gerberick, Li-Zhen He, Tibor Keler, Lawrence J. Thomas, William P. Lafuse, Larry S. Schlesinger
Publikováno v:
Cell Reports, Vol 21, Iss 1, Pp 126-140 (2017)
Despite its prominent role as a C-type lectin (CTL) pattern recognition receptor, mannose receptor (MR, CD206)-specific signaling molecules and pathways are unknown. The MR is highly expressed on human macrophages, regulating endocytosis, phagocytosi
Externí odkaz:
https://doaj.org/article/5a0913fd2f82491fa5938f195a20e76c
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007585 (2019)
Nuclear receptors (NRs) are ligand-activated transcription factors that are expressed in a variety of cells, including macrophages. For decades, NRs have been therapeutic targets because their activity can be pharmacologically modulated by specific l
Externí odkaz:
https://doaj.org/article/a9dac933679a464ab9c3ab55c977fba1
Autor:
Natalie Zimmermann, Verena Thormann, Bo Hu, Anne‐Britta Köhler, Aki Imai‐Matsushima, Camille Locht, Eusondia Arnett, Larry S Schlesinger, Thomas Zoller, Mariana Schürmann, Stefan HE Kaufmann, Hedda Wardemann
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 11, Pp 1325-1339 (2016)
Abstract Accumulating evidence from experimental animal models suggests that antibodies play a protective role against tuberculosis (TB). However, little is known about the antibodies generated upon Mycobacterium tuberculosis (MTB) exposure in humans
Externí odkaz:
https://doaj.org/article/b7388aeba1964598a12b5101a04b9133
Autor:
Eusondia Arnett, Ashlee M Weaver, Kiersten C Woodyard, Maria J Montoya, Michael Li, Ky V Hoang, Andrew Hayhurst, Abul K Azad, Larry S Schlesinger
Publikováno v:
PLoS Pathogens, Vol 14, Iss 6, p e1007100 (2018)
Peroxisome proliferator-activated receptor (PPAR)γ is a global transcriptional regulator associated with anti-inflammatory actions. It is highly expressed in alveolar macrophages (AMs), which are unable to clear the intracellular pathogen Mycobacter
Externí odkaz:
https://doaj.org/article/c0f1aa418ee74f7fbdf7bf3373fca157
Autor:
Stephen Vadia, Eusondia Arnett, Anne-Cécile Haghighat, Elisabeth M Wilson-Kubalek, Rodney K Tweten, Stephanie Seveau
Publikováno v:
PLoS Pathogens, Vol 7, Iss 11, p e1002356 (2011)
Intracellular pathogens have evolved diverse strategies to invade and survive within host cells. Among the most studied facultative intracellular pathogens, Listeria monocytogenes is known to express two invasins-InlA and InlB-that induce bacterial i
Externí odkaz:
https://doaj.org/article/310b350d4cfd4f7c9606eae8cd4a4437
Autor:
Wolfgang Sadee, Ian H. Cheeseman, Audrey Papp, Maciej Pietrzak, Michal Seweryn, Xiaofei Zhou, Shili Lin, Amanda M. Williams, Eusondia Arnett, Abul K. Azad, Larry S. Schlesinger
Mycobacterium tuberculosis(M.tb) establishes residence and growth in human alveolar macrophages (AMs). Large inter-individual variation inM.tb-AM interactions is a potential early indicator of TB risk and efficacy of therapies and vaccines. Herein, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab228aaba52700666df5c9d19599e81b
https://doi.org/10.1101/2022.03.14.484235
https://doi.org/10.1101/2022.03.14.484235
