Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eunsoo Yu"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The methods for investigation of DNA-binding proteins require site-selective chemical modifications to be introduced into oligonucleotides. Here, the authors report a chemo- and regioselective method for the modification of unpaired guanosines in sin
Externí odkaz:
https://doaj.org/article/a87f440e559c43fb9ceb54897722cfc7
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
[2 + 2] cycloaddition of alkynes with alkenes would normally require UV light irradiation. Here, the authors report an alkyne–alkene [2 + 2] cycloaddition based on visible light energy transfer photocatalysis, both inter- and intramolecularly, to a
Externí odkaz:
https://doaj.org/article/6bc8f7e905284ef1bc6beb5c43d30257
Autor:
Ju Youn Lee, Seung Hoon Han, Min Hee Park, Im-Sook Song, Min-Koo Choi, Eunsoo Yu, Cheol-Min Park, Hee-Jin Kim, Seung Hyun Kim, Edward H. Schuchman, Hee Kyung Jin, Jae-sung Bae
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Neuronal sphingosine kinase 1 (SphK1) acetylates COX2 which is needed for microglial phagocytosis activity, and release of pro-resolving mediators (SPMs) from neurons. Here the authors examine how SphK1-mediates COX2 acetylation, and how this leads t
Externí odkaz:
https://doaj.org/article/3035df8592594ac98f3be370c56a59d8
Publikováno v:
Organicbiomolecular chemistry. 20(37)
The synthesis of benzothiophenes through electrosynthesis under oxidant- and metal-free conditions has been discovered. Electrolysis of symmetrical 2-alkenylaryl disulfides using an undivided cell leads to the formation of the corresponding benzothio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582663be9d695de2064bb278c5ffe872
https://pubmed.ncbi.nlm.nih.gov/36106773
https://pubmed.ncbi.nlm.nih.gov/36106773
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Site-selective modification of oligonucleotides serves as an indispensable tool in many fields of research including research of fundamental biological processes, biotechnology, and nanotechnology. Here we report chemo- and regioselective modificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcbfd8d0624a88d271716d9a6d16691
https://doaj.org/article/a87f440e559c43fb9ceb54897722cfc7
https://doaj.org/article/a87f440e559c43fb9ceb54897722cfc7
Publikováno v:
Angewandte Chemie International Edition. 59:11886-11891
Oxidative [3+3] cycloadditions offer an efficient route for six-membered-ring formation. This approach has been realized based on an electrochemical oxidative coupling of indoles/enamines with active methylene compounds followed by tandem 6π-electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842f15bf7d6076687f4a5d959ec34aba
https://doi.org/10.1002/anie.202003364
https://doi.org/10.1002/anie.202003364
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
UV-activated alkyne–alkene [2 + 2] cycloaddition has served as an important tool to access cyclobutenes. Although broadly adopted, the limitations with UV light as an energy source prompted us to explore an alternative method. Here we report alkyne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9f93fac2f059d389758bef0fc95bed
http://link.springer.com/article/10.1038/s41467-020-16283-9
http://link.springer.com/article/10.1038/s41467-020-16283-9
Autor:
Hee Jin Kim, Seung Hyun Kim, Cheol-Min Park, Jae-sung Bae, Ju Youn Lee, Min-Koo Choi, Min Hee Park, Eunsoo Yu, Hee Kyung Jin, Edward H. Schuchman, Seung Hoon Han, Im-Sook Song
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications
Sphingosine kinase1 (SphK1) is an acetyl-CoA dependent acetyltransferase which acts on cyclooxygenase2 (COX2) in neurons in a model of Alzheimer’s disease (AD). However, the mechanism underlying this activity was unexplored. Here we show that N-ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782a4eb0726efb66ab89568cfe37f061
https://doaj.org/article/3035df8592594ac98f3be370c56a59d8
https://doaj.org/article/3035df8592594ac98f3be370c56a59d8
Publikováno v:
Organic letters. 22(14)
The synthesis of versatile scaffold indolopyrans based on C-C radical-radical cross-coupling under metal-free conditions is described. The reaction involving single electron transfer between coupling partners followed by cage collapse allows highly s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31831ded37d4a50a1d6df24e78170763
https://pubmed.ncbi.nlm.nih.gov/32628496
https://pubmed.ncbi.nlm.nih.gov/32628496