Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eunsin Ha"'
Autor:
Seok-Jun Kim, Kyung-Hee Chun, Hyunwoo Park, Sanghoon Lee, Seul Lee, Kim Dongin, Hyeok Gu Kang, Weon-Kyoo You, Da-Hyun Kim, Ahn Jinhyung, Han Woong Lee, Eunsin Ha, Dong-Hoon Yoem
Publikováno v:
BMB Reports
Notch signaling has been identified as a critical pathway in gastric cancer (GC) progression and metastasis, and inhibition of Delta-like ligand 4 (DLL4), a Notch ligand, is suggested as a potent therapeutic approach for GC. Expression of both DLL4 a
Autor:
Jeeyun Lee, SeungTae Kim, JungYong Hong, YoungSuk Park, JoonOh Park, WonKi Kang, Keun-Wook Lee, Jin Won Kim, Ji-Won Kim, Se Hyun Kim, Eunsin Ha, Sangmi Lee, JongRan Kim, Weon-Kyoo You
Publikováno v:
Molecular Cancer Therapeutics. 20:P02-03
VEGF blockade is a validated therapeutic approach and anti-VEGF antibodies are established components of several standard regimens for various malignancies. However, the overall response rate to single agent VEGF blockers is extremely low and many pa
Autor:
Han-Byul Lee, Sunju Lee, Kim Dongin, Ahn Jinhyung, Yong-Soo Choi, Ilhwan Ryu, Sanghoon Lee, Yoseob Lee, Weon-Kyoo You, Eunsin Ha, Sung Byungje, Yeom Donghoon
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 241, p 241 (2021)
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 241, p 241 (2021)
Volume 22
Issue 1
Delta-like-ligand 4 (DLL4) is a promising target to augment the effects of VEGF inhibitors. A simultaneous blockade of VEGF/VEGFR and DLL4/Notch signaling pathways leads to more potent anti-cancer effects by synergistic anti-angiogenic mechanisms in
Autor:
Hoon-Kyo Kim, Doo-Hong Park, Young Suk Park, Ho Yeong Lim, Eunsin Ha, Su Jin Lee, Neunggyu Park, Joon Oh Park, Seung Hoon Kim, Sang-Hoon Lee, Won Ki Kang, Se Hoon Park, Weon-Kyoo You, Jeeyun Lee
Publikováno v:
Journal of Clinical Oncology. 37:3023-3023
3023 Background: Antiangiogenic therapy has been a successful clinical strategy for the treatment of various cancer types. To date, all approved antiangiogenic drugs primarily inhibit the VEGF/VEGFR pathway. Delta-like ligand 4 (DLL4) has been identi
Publikováno v:
FEBS Letters. 583:2720-2726
Steatosis is an established risk factor for disease progression in cases of chronic hepatitis C. Recently it was demonstrated that Hepatitis C virus (HCV) core and non-structural (NS) 2 proteins (NS2) induce lipid accumulation in hepatic cells. Howev