Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Eunkyeong Jung"'
Publikováno v:
Small Science, Vol 4, Iss 7, Pp n/a-n/a (2024)
Intratumoral immunotherapies are those that are administered directly into a tumor to remodel the local tumor microenvironment and stimulate systemic anti‐tumor immunity. Small molecule toll‐like receptor (TLR) agonists are undergoing development
Externí odkaz:
https://doaj.org/article/035699a60964485381650ac24c04dcf9
Autor:
Young Hun Chung, Zhongchao Zhao, Eunkyeong Jung, Anthony O. Omole, Hanyang Wang, Lucas Sutorus, Nicole F. Steinmetz
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract The key challenge in cancer treatment is prevention of metastatic disease which is therapeutically resistant and carries poor prognoses necessitating efficacious prophylactic approaches that prevent metastasis and recurrence. It is previousl
Externí odkaz:
https://doaj.org/article/bb757b911d0641339814a8f2c442a05a
Autor:
Matthew D. Shin, Eunkyeong Jung, Miguel A. Moreno‐Gonzalez, Oscar A. Ortega‐Rivera, Nicole F. Steinmetz
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 1, Pp n/a-n/a (2024)
Abstract Our lab demonstrated that intratumoral Cowpea mosaic virus (CPMV) is a potent antitumor immunotherapy when used as in situ vaccine. As we pave the way for human clinical translation, formulation chemistry needs to be optimized for long‐ter
Externí odkaz:
https://doaj.org/article/7d5a2e44f4174f4c856fae619e7e70c4
Autor:
Donghyuck Yoo, Eunkyeong Jung, Joungyoun Noh, Hyejin Hyun, Semee Seon, Seri Hong, Dongin Kim, Dongwon Lee
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 10070-10077 (2019)
Externí odkaz:
https://doaj.org/article/74dd33eeac1640029d3c894bd1ec2e24
Autor:
Eunkyeong Jung, Chenkai Mao, Misha Bhatia, Edward C. Koellhoffer, Steven N. Fiering, Nicole F. Steinmetz
Publikováno v:
Mol Pharm
Cowpea mosaic virus (CPMV) has been developed as a promising nanoplatform technology for cancer immunotherapy; when applied as in situ vaccine, CPMV exhibits potent, systemic, and durable efficacy. While CPMV is not infectious to mammals, it is infec
Autor:
Mansur A. Ghani, Amandip Bangar, Yunpeng Yang, Eunkyeong Jung, Consuelo Sauceda, Tyler Mandt, Sourabh Shukla, Nicholas J.G. Webster, Nicole F. Steinmetz, Isabel G. Newton
Publikováno v:
Journal of Vascular and Interventional Radiology.
Autor:
Young Hun Chung, Ortega-Rivera, Oscar A., Volckaert, Britney A., Eunkyeong Jung, Zhongchao Zhao, Steinmetz, Nicole F.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/24/2023, Vol. 120 Issue 43, p1-11, 33p
Publikováno v:
Biomaterials science. 10(21)
Compared to normal cells, cancer cells are more susceptible to insults of prooxidants that generate ROS (reactive oxygen species) or scavenge antioxidants such as glutathione (GSH). Cancer cells undergo immunogenic cell death (ICD) by elevated oxidat
Autor:
Eunkyeong Jung, Soonyoung Kwon, Nanhee Song, Nuri Kim, Hanui Jo, Manseok Yang, Sangjun Park, Chunho Kim, Dongwon Lee
Publikováno v:
Biomaterials. 298:122127
Oxidative Stress Amplifying Polyprodrug Micelles as Drug Carriers for Combination Anticancer Therapy
Autor:
Yujin Lee, Nanhee Song, Nuri Kim, Manseok Yang, Gayoung Kwon, Hyejin Hyeon, Eunkyeong Jung, Seong-Cheol Park, Chunho Kim, Dongwon Lee
Publikováno v:
Biomacromolecules. 23(9)
Cancer cells are more vulnerable to reactive oxygen species (ROS)-mediated oxidative stress than normal cells due to disturbed redox balance. It can be postulated that ROS-generating drug carriers exert anticancer actions, leading to combination anti