Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Eunju, Hurh"'
Autor:
Maria C. Foss-Freitas, Baris Akinci, Adam Neidert, Victoria J. Bartlett, Eunju Hurh, Ewa Karwatowska-Prokopczuk, Elif A. Oral
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background Familial partial lipodystrophy (FPLD) is a rare disease characterized by selective loss of peripheral subcutaneous fat, associated with dyslipidemia and diabetes mellitus. Reductions in circulating levels of ANGPTL3 are associated
Externí odkaz:
https://doaj.org/article/50ffdd79d6e14f6093c4b51acb7bcb51
Autor:
Ewa Karwatowska‑Prokopczuk, Anastasia Lesogor, Jing-He Yan, Eunju Hurh, Angelika Hoenlinger, Alison Margolskee, Shuting Xia, Sotirios Tsimikas
Publikováno v:
Journal of Clinical Lipidology. 17:181-188
Pelacarsen is a liver-targeted antisense oligonucleotide that potently lowers lipoprotein(a) [Lp(a)] levels. Its safety and efficacy in diverse populations has not been extensively studied.To assess the effect of pelacarsen, including monthly dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881353bc28a966e5c7705b04cba83629
https://doi.org/10.1016/j.jacl.2022.12.001
https://doi.org/10.1016/j.jacl.2022.12.001
Autor:
Colby S. Shemesh, Rosie Z. Yu, Mark S. Warren, Michael Liu, Mirza Jahic, Brandon Nichols, Noah Post, Song Lin, Daniel A. Norris, Eunju Hurh, Jane Huang, Tanya Watanabe, Scott P. Henry, Yanfeng Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 34-47 (2017)
Antisense oligonucleotides are metabolized by nucleases and drug interactions with small drug molecules at either the cytochrome P450 (CYP) enzyme or transporter levels have not been observed to date. Herein, a comprehensive in vitro assessment of th
Externí odkaz:
https://doaj.org/article/e207d7ae85c046919a7c54818f631e90
Autor:
Elif A. Oral, Abhimanyu Garg, Joseph Tami, Eric A. Huang, Louis St.L. O'Dea, Hartmut Schmidt, Anatoly Tiulpakov, Ann Mertens, Veronica J. Alexander, Lynnetta Watts, Eunju Hurh, Joseph L. Witztum, Richard S. Geary, Sotirios Tsimikas
Publikováno v:
Journal of Clinical Lipidology. 16:833-849
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a511815ca92594eaecdb3be627b967ea
https://doi.org/10.1016/j.jacl.2022.08.008
https://doi.org/10.1016/j.jacl.2022.08.008
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Figure 3 from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2934ed8c6f207f77eea17ceb99211e41
https://doi.org/10.1158/1535-7163.22486041.v1
https://doi.org/10.1158/1535-7163.22486041.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
AMG 386 is an investigational first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the interaction of angiopoietin-1 (Ang1) and Ang2 with their receptor, Tie2. Although the therapeutic value of blocking Ang2 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fc85f3746b4b3881e43684fd11d58a
https://doi.org/10.1158/1535-7163.c.6532206.v1
https://doi.org/10.1158/1535-7163.c.6532206.v1
Autor:
Alain C. Mita, Reinhard Dummer, Dereck D. Amakye, Kristine L. Rose, Eunju Hurh, Camille Granvil, Lin Yang, Melissa A. Moles, Yaping Shou, Devalingam Mahalingam, John Sarantopoulos, Jose Baselga, Christian P. Turtschi, Ronald G. Stoller, Anne L. Thomas, Hussein A. Tawbi, Jordi Rodon
PDF file - 97K, Reduction in glioma-associated oncogene homolog 1 in patients with available tumor and matching skin specimens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1140d13f47583fd1eb58a33f2ce7eef4
https://doi.org/10.1158/1078-0432.22450847
https://doi.org/10.1158/1078-0432.22450847
Autor:
Alain C. Mita, Reinhard Dummer, Dereck D. Amakye, Kristine L. Rose, Eunju Hurh, Camille Granvil, Lin Yang, Melissa A. Moles, Yaping Shou, Devalingam Mahalingam, John Sarantopoulos, Jose Baselga, Christian P. Turtschi, Ronald G. Stoller, Anne L. Thomas, Hussein A. Tawbi, Jordi Rodon
PDF file - 29K, Chemical structures of sonidegib and cyclopamine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c2cdb2ec08f0741538518a6fa3b997
https://doi.org/10.1158/1078-0432.22450856.v1
https://doi.org/10.1158/1078-0432.22450856.v1
Autor:
Jonathan D. Oliner, Robert Radinsky, Richard Kendall, Tom Boone, Luke Li, Donald M. McDonald, Beverly L. Falcón, Isaac J. Hayward, Anthony Ndifor, Shao Xiong Wang, Linh Nguyen, Eunju Hurh, Russell Cattley, Grant Shimamoto, Eric Hsu, Mark L. Michaels, Seog Joon Han, Haejin Kim, David Cordover, Paul Hughes, Sean Caenepeel, Karen Rex, Ling Wang, James McCabe, Brad Bolon, Juan Estrada, Ji-Rong Sun, Tani Ann Lee, Dongyin Yu, Juan Leal, Stephen Kaufman, Hosung Min, James Bready, Angela Coxon
Supplementary Methods, Figure Legends, and References from Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2–Neutralizing Peptibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f1f07abbb748f03b8d216b421c4503
https://doi.org/10.1158/1535-7163.22486035
https://doi.org/10.1158/1535-7163.22486035
Autor:
Alain C. Mita, Reinhard Dummer, Dereck D. Amakye, Kristine L. Rose, Eunju Hurh, Camille Granvil, Lin Yang, Melissa A. Moles, Yaping Shou, Devalingam Mahalingam, John Sarantopoulos, Jose Baselga, Christian P. Turtschi, Ronald G. Stoller, Anne L. Thomas, Hussein A. Tawbi, Jordi Rodon
PDF file - 71K, Supplementary data includes a table summarizing cohort enrollment and dose-limiting toxicities (Table S1) and a table showing the association between tumor response and Hh pathway activity in medulloblastoma and basal cell carcinoma (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b07f14e646a5aafc938b4bbaad02fc
https://doi.org/10.1158/1078-0432.22450844
https://doi.org/10.1158/1078-0432.22450844