Výsledky vyhledávání - "Eunice M Betouke Ongwe"

Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial

Publikováno v: The Lancet Infectious Diseases
The Lancet Infectious Diseases, 21(2), 275-285. ELSEVIER SCI LTD

Background Hookworms cause substantial morbidity in children and women of reproductive age. The control strategy of mass drug administration is suboptimal, hence the need for a vaccine. Necator americanus aspartic protease-1 (Na-APR-1) and N american

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb55fd2ffad7c271f775a2b2d818cb0
https://hdl.handle.net/1887/3214678

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Controlled Human Malaria Infection of Healthy Adults With Lifelong Malaria Exposure to Assess Safety, Immunogenicity, and Efficacy of the Asexual Blood Stage Malaria Vaccine Candidate GMZ2

Autor: Marguerite Massinga-Loembe, José Francisco Fernandes, Ulysse Ateba-Ngoa, Jean Claude Dejon-Agobé, Peter G. Kremsner, Julie Engelhorn, Michael Theisen, Ayola A. Adegnika, Eunice M Betouke Ongwe, Albert Lalremruata, Yoanne D. Mouwenda, Odilon Nouatin, Bertrand Lell, Stephen L. Hoffman, Jean Ronald Edoa, Benjamin Mordmüller, Meral Esen, Andreas Homoet, B. Kim Lee Sim

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69(8)

BackgroundGMZ2 is a recombinant malaria vaccine inducing immune responses against Plasmodium falciparum (Pf) merozoite surface protein-3 and glutamate-rich protein. We used standardized controlled human malaria infection (CHMI) to assess the efficacy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bceb87f9875702b6bf09c35c6b3529
https://pubmed.ncbi.nlm.nih.gov/30561539

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