Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eunice J. Park"'
Autor:
Veronica G Beaudry, Dadi Jiang, Rachel L Dusek, Eunice J Park, Stevan Knezevich, Katie Ridd, Hannes Vogel, Boris C Bastian, Laura D Attardi
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001168 (2010)
Dysregulated cell-cell adhesion plays a critical role in epithelial cancer development. Studies of human and mouse cancers have indicated that loss of adhesion complexes known as adherens junctions contributes to tumor progression and metastasis. In
Externí odkaz:
https://doaj.org/article/693419627b644e96adabff8564c09e92
Autor:
Bichchau Nguyen, Suzanne B.R. Jacobs, Navneeta Pathak, Rebecca A. Ihrie, Veronica G. Beaudry, Laura D. Attardi, Eunice J. Park
Publikováno v:
Dermatology Research and Practice, Vol 2010 (2010)
Dermatology Research and Practice
Dermatology Research and Practice
Epithelial wound closure is a complex biological process that relies on the concerted action of activated keratinocytes and dermal fibroblasts to resurface and close the exposed wound. Modulation of cell-cell adhesion junctions is thought to facilita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ffba5ef9a14b6e027eeaf20d72a20e
https://doi.org/10.1155/2010/759731
https://doi.org/10.1155/2010/759731
Autor:
Hannes Vogel, Daniela Kenzelmann Broz, Stephano S. Mello, Dadi Jiang, Colleen A. Brady, Laura D. Attardi, Eunice J. Park
Publikováno v:
Genetics.
The essential role of p53 in tumor suppression is highlighted by the observations that p53 is mutated in over half of human cancers and that p53-null mice are highly predisposed to developing cancer. Although p53 is thought to suppress cancer by indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb7b0a4e09552fb1f5628f33c51e188a
https://doi.org/10.1158/1538-7445.panca2012-b12
https://doi.org/10.1158/1538-7445.panca2012-b12
Autor:
Eunice Y. Lee, Laura D. Attardi, Thomas M. Johnson, Matthew P. Scott, Eunice J. Park, Dadi Jiang, Colleen A. Brady
Over half of all human cancers, of a wide variety of types, sustain mutations in the p53 tumor suppressor gene. Although p53 limits tumorigenesis through the induction of apoptosis or cell cycle arrest, its molecular mechanism of action in tumor supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4232f3665491934c22066f3c32ffab21
https://europepmc.org/articles/PMC3193184/
https://europepmc.org/articles/PMC3193184/
Autor:
Lesley A. Jarvis, Daniela Kenzelmann Broz, Anthony N. Karnezis, Colleen A. Brady, Margaret M. Kozak, Eunice J. Park, Dadi Jiang, Laura D. Attardi, Shashwati Basak, Stephano S. Mello, Thomas M. Johnson, Margaret McLaughlin
Publikováno v:
Cell. (4):571-583
The molecular basis for p53-mediated tumor suppression remains unclear. Here, to elucidate mechanisms of p53 tumor suppression, we use knockin mice expressing an allelic series of p53 transcriptional activation mutants. Microarray analysis reveals th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c232f24241d0403351240cb2b2b8b2