Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Eunice Hui Yen Li"'
Autor:
Eunice Hui Yen Li, Barindra Sana, Timothy Ho, Ding Ke, Farid J. Ghadessy, Hung A. Duong, Jayasree Seayad
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Biocatalytic C-H halogenation is becoming increasingly attractive due to excellent catalyst-controlled selectivity and environmentally benign reaction conditions. Significant efforts have been made on enzymatic halogenation of industrial arenes in a
Externí odkaz:
https://doaj.org/article/70f54ed26d54420a9b110cbc8ee41f51
Autor:
Barindra Sana, Ding Ke, Eunice Hui Yen Li, Timothy Ho, Jayasree Seayad, Hung A. Duong, Farid J. Ghadessy
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1841 (2022)
Halogenation of bioactive peptides via incorporation of non-natural amino acid derivatives during chemical synthesis is a common strategy to enhance functionality. Bacterial tyrptophan halogenases efficiently catalyze regiospecific halogenation of th
Externí odkaz:
https://doaj.org/article/f48b338e0b4a4a07b8e703bd51df862a
Autor:
Barindra Sana, Ding Ke, Eunice Hui Yen Li, Timothy Ho, Jayasree Seayad, Hung A Duong, Farid J Ghadessy
We demonstrate novel in vitro halogenation of peptides by halogenase enzymes, and identify the (G/S)GW motif (HaloTryp Tag) as a preferred substrate. We further derive PyrH halogenase mutants showing improved halogenation of the HaloTryp Tag, both as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c242b1bc837ef1d5f9530c958f50bc8
https://doi.org/10.1101/2022.07.19.500721
https://doi.org/10.1101/2022.07.19.500721
