Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Eunhwa, Ko"'
Autor:
Soochan Kim, Eunhwa Ko, Hwan Geun Choi, Daekwon Kim, Monica Luchi, Bernard Khor, Sunghwan Kim
Publikováno v:
Journal of Translational Autoimmunity, Vol 6, Iss , Pp 100185- (2023)
Dual-specificity tyrosine phosphorylation-regulated kinase 1 A (DYRK1A) has been proposed as a novel regulator of adaptive immune homeostasis through modulating T cell polarization. Thus, DYRK1A could present a potential target in autoimmune disorder
Externí odkaz:
https://doaj.org/article/37e1bd99114844d1b6ad44b987dd352f
Autor:
Yikyung Ko, Jihye yoo, Hong-ryul Jung, Hyerim Lim, YeongDeok Lee, Se Hyuk Kim, Dong Guk Shin, Serin Cho, Myung hoe Heo, Haelee Kim, Ha Yeon Cho, Ah Reum Han, Eunhwa Ko, Hwan Geun Choi, Deakwon Kim, Sunghwan Kim
Publikováno v:
Cancer Research. 83:P1-11
The brain is a common target organ for breast cancer metastasis, and the risk of brain metastasis is usually high for patients with HER2-positive breast cancer. While T-DXd showed positive results in HER2-positive breast cancer brain metastasis (BCBM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2312641c1587a804507c69288b933ae0
https://doi.org/10.1158/1538-7445.sabcs22-p1-11-03
https://doi.org/10.1158/1538-7445.sabcs22-p1-11-03
Autor:
Ju-Young Lee, Jin Han Nam, Youngpyo Nam, Hye Yeon Nam, Gwangho Yoon, Eunhwa Ko, Sang-Bum Kim, Mahealani R Bautista, Christina C Capule, Takaoki Koyanagi, Geoffray Leriche, Hwan Geun Choi, Jerry Yang, Jeongyeon Kim, Hyang-Sook Hoe
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-23 (2018)
Abstract Background Neuroinflammation is associated with neurodegenerative diseases, including Alzheimer’s disease (AD). Thus, modulating the neuroinflammatory response represents a potential therapeutic strategy for treating neurodegenerative dise
Externí odkaz:
https://doaj.org/article/dfda851a974a40adb2093666dc7b1d5f
Autor:
Hong-ryul Jung, Sunghwan Kim, Jihye Yoo, Chan mi Park, Somi Lee, Hyoju Lee, Youngyi Lee, Jinhee Park, Kyungah Seo, Dong-Hyuk Seo, Eunhwa Ko, Jung Beom Son, Deakwon Kim, Hwan Geun Choi, Nam Doo Kim
Publikováno v:
Cancer Research. 82:P2-13
Breast cancer (BC) is the second most common cancer associated with brain metastasis (BM) and among patients with breast cancer brain metastasis (BCBM), human epidermal growth factor receptor 2 (HER2)-positive breast cancer is most likely to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3170c068e75cf611b8cd2ba82f43cac3
https://doi.org/10.1158/1538-7445.sabcs21-p2-13-15
https://doi.org/10.1158/1538-7445.sabcs21-p2-13-15
Autor:
Seo Kyung Ah, Son Jung Beom, Ikyon Kim, Jun Goo Jee, Nam Doo Kim, Kim Hyunkyung, Haelee Kim, Eunhwa Ko, Hwan Geun Choi, Younho Lee, Ha Yeon Cho
Publikováno v:
Journal of Medicinal Chemistry. 64:6985-6995
Triple-negative breast cancer (TNBC) is an aggressive breast-cancer subtype associated with poor prognosis and high relapse rates. Monopolar spindle 1 kinase (MPS1) is an apical dual-specificity protein kinase that is over-expressed in TNBC. We herei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd1e225ff0d0ed781f23a424e08089d
https://doi.org/10.1021/acs.jmedchem.1c00542
https://doi.org/10.1021/acs.jmedchem.1c00542
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89617 (2014)
A library of peptidomimetics was assembled combinatorially into dimers on a triazine-based core. The pharmacophore corresponds to β-turns of the neurotrophin polypeptides neurotrophin-3 (NT-3), nerve growth factor (NGF), or brain-derived neurotrophi
Externí odkaz:
https://doaj.org/article/1d45cf5a339440e39a7fc017f9cb33fe
Autor:
Younho, Lee, Hyunkyung, Kim, Haelee, Kim, Ha Yeon, Cho, Jun-Goo, Jee, Kyung-Ah, Seo, Jung Beom, Son, Eunhwa, Ko, Hwan Geun, Choi, Nam Doo, Kim, Ikyon, Kim
Publikováno v:
Journal of medicinal chemistry. 64(10)
Triple-negative breast cancer (TNBC) is an aggressive breast-cancer subtype associated with poor prognosis and high relapse rates. Monopolar spindle 1 kinase (MPS1) is an apical dual-specificity protein kinase that is over-expressed in TNBC. We herei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5318148535a7bed12adc0dfbcf524041
https://pubmed.ncbi.nlm.nih.gov/33942608
https://pubmed.ncbi.nlm.nih.gov/33942608
Autor:
Somi Lee, Eunhwa Ko, Nam Doo Kim, Sunghwan Kim, Hwan Geun Choi, Kim Hwan, Ji Eun Choi, Younho Lee, Chanmi Park, Jihye Yoo, Son Jung Beom, Daekwon Kim, Park Jin-Hee, Youngyi Lee
Publikováno v:
Cancer Research. 81:LB139-LB139
Human epidermal growth factor receptor 2 (HER2) amplification is one of oncogenic drivers most found in breast cancer but also occurs in multiple other tumor types. Approximately 10-30% of patients with breast cancer develop brain metastases (BCBM),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b365ccbefb06004be8e8ee65e5554603
https://doi.org/10.1158/1538-7445.am2021-lb139
https://doi.org/10.1158/1538-7445.am2021-lb139
Autor:
Geoffray Leriche, Gwangho Yoon, Hye Yeon Nam, Jin Han Nam, Kim Sang Bum, Juyoung Lee, Christina C. Capule, Hwan Geun Choi, Jeongyeon Kim, Takaoki Koyanagi, Hyang-Sook Hoe, Eunhwa Ko, Jerry Yang, Mahealani R. Bautista, Youngpyo Nam
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-23 (2018)
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-23 (2018)
Background Neuroinflammation is associated with neurodegenerative diseases, including Alzheimer’s disease (AD). Thus, modulating the neuroinflammatory response represents a potential therapeutic strategy for treating neurodegenerative diseases. Sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad159b33bf59a658b236738c5222ac16
https://pubmed.ncbi.nlm.nih.gov/30309372
https://pubmed.ncbi.nlm.nih.gov/30309372
Autor:
Lee, Ju-Young, Nam, Jin, Youngpyo Nam, Nam, Hye, Gwangho Yoon, Eunhwa Ko, Sang-Bum Kim, Mahealani Bautista, Capule, Christina, Takaoki Koyanagi, Geoffray Leriche, Choi, Hwan Geun, Yang, Jerry, Jeongyeon Kim, Hyang-Sook Hoe
Figure S1. Post-treatment with CA140 at 5 μM only significantly reduced LPS-induced IL-1β mRNA levels. Figure S2. Post-treatment with CA140 significantly reduced LPS-induced proinflammatory cytokine levels in a longer treatment. Figure S3. Pretreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84118a9fe61eb72c856642d140ff4318
