Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eung Jun Im"'
Autor:
Eung Jun Im, Anthony J Bais, Wen Yang, Qiangzhong Ma, Xiuyang Guo, Steven M Sepe, Richard P Junghans
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Transduction and expression procedures in gene therapy protocols may optimally transfer more than a single gene to correct a defect and/or transmit new functions to recipient cells or organisms. This may be accomplished by transduction with two (or m
Externí odkaz:
https://doaj.org/article/4c4ee8076b554c74bb55a77687810653
Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges.
Autor:
Eung-Jun Im, Jessie P Hong, Yaowaluck Roshorm, Anne Bridgeman, Sven Létourneau, Peter Liljeström, Mary Jane Potash, David J Volsky, Andrew J McMichael, Tomáš Hanke
Publikováno v:
PLoS Pathogens, Vol 7, Iss 5, p e1002041 (2011)
Immunodominance in T cell responses to complex antigens like viruses is still incompletely understood. Some data indicate that the dominant responses to viruses are not necessarily the most protective, while other data imply that dominant responses a
Externí odkaz:
https://doaj.org/article/57b8c2a950d448ea9a709abb743a6a71
Autor:
Sven Létourneau, Eung-Jun Im, Tumelo Mashishi, Choechoe Brereton, Anne Bridgeman, Hongbing Yang, Lucy Dorrell, Tao Dong, Bette Korber, Andrew J. McMichael, Tomáš Hanke
Publikováno v:
PLoS ONE, Vol 6, Iss 3 (2011)
Externí odkaz:
https://doaj.org/article/665799d7c59d40d683e96aee15d19384
Autor:
Narcís Saubi, Eung-Jun Im, Raquel Fernández-Lloris, Olga Gil, Pere-Joan Cardona, Josep Maria Gatell, Tomáš Hanke, Joan Joseph
Publikováno v:
Clinical and Developmental Immunology, Vol 2011 (2011)
We have evaluated the influence of age and immunization routes for induction of HIV-1- and M. tuberculosis-specific immune responses after neonatal (7 days old) and adult (7 weeks old) BALB/c mice immunization with BCG.HIVA222 prime and MVA.HIVA boos
Externí odkaz:
https://doaj.org/article/c783db36910c4221aa4ee9d6e83f50d8
Autor:
Sven Létourneau, Eung-Jun Im, Tumelo Mashishi, Choechoe Brereton, Anne Bridgeman, Hongbing Yang, Lucy Dorrell, Tao Dong, Bette Korber, Andrew J McMichael, Tomás Hanke
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e984 (2007)
BACKGROUND:One of the big roadblocks in development of HIV-1/AIDS vaccines is the enormous diversity of HIV-1, which could limit the value of any HIV-1 vaccine candidate currently under test. METHODOLOGY AND FINDINGS:To address the HIV-1 variation, w
Externí odkaz:
https://doaj.org/article/0d11f9c277e444f483ae1fa7a1fd0edf
Autor:
Fred R. Frankel, Dan H. Barouch, Erica N. Borducchi, Anna McNally, Nicholas M. Provine, Eung-Jun Im, Sufen Li
Publikováno v:
Journal of Virology. 87:4751-4755
A human immunodeficiency virus type 1 (HIV-1) vaccine that induces potent immune responses in the gastrointestinal mucosa would be highly desirable. Here we show that attenuated recombinant Listeria monocytogenes , administered orally utilizing its n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae81c92fe22918cf370abce09cc5e447
https://doi.org/10.1128/jvi.03085-12
https://doi.org/10.1128/jvi.03085-12
Autor:
Tomáš Hanke, Eung-Jun Im
A vaccine against HIV Type 1 (HIV-1) is urgently needed. Modified vaccinia virus Ankara is an attenuated smallpox vaccine which can be adapted to express HIV-1 antigens. In this review, we discuss the features which make modified vaccinia virus Ankar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b432fc3af2b8d00e85b4f03388ce629
https://ora.ox.ac.uk/objects/uuid:8390a6cd-254c-4cb0-8e20-627ea273cf35
https://ora.ox.ac.uk/objects/uuid:8390a6cd-254c-4cb0-8e20-627ea273cf35
Autor:
Tomáš Hanke, Joe Parker, Charles Bourne, Eung Jun Im, Nicola Borthwick, Anne Bridgeman, Shamit Soneji, Jerald C. Sadoff, Joan Joseph, Maximillian Rosario, John Fulkerson
Although major inroads into making antiretroviral therapy available in resource-poor countries have been made, there is an urgent need for an effective vaccine administered shortly after birth, which would protect infants from acquiring human immunod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b491c2dfa47d44259b38c43ddb983ec
https://doi.org/10.1128/jvi.00726-10
https://doi.org/10.1128/jvi.00726-10
Autor:
Carolyn Williamson, Eung-Jun Im, Ralf Wagner, Natasha Larke, Andrew J. McMichael, Anna-Lise Williamson, Tomáš Hanke
We assessed in mice whether broad CD8+ T cell responses capable of efficient recognition of multiple HIV-1 clades could be induced using current single-clade vaccine constructs that were or will be used in clinical trials in Europe and Africa. We fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7464b0e7c2f473955ac1487c5159a0
https://doi.org/10.1002/eji.200636711
https://doi.org/10.1002/eji.200636711
As a part of a long-term effort to develop vaccine against HIV-1 clade A inducing protective T cell responses in humans, we run mutually complementing studies in humans and non-human primates (NHP) with the aim to maximize vaccine immunogenicity. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99391abd965ef17e17c439b87e023176
https://ora.ox.ac.uk/objects/uuid:692de478-f339-4fd0-9e92-9bb0c3c0d2c6
https://ora.ox.ac.uk/objects/uuid:692de478-f339-4fd0-9e92-9bb0c3c0d2c6