Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Eunchong Park"'
Autor:
Angela Rivera, Won Young Lim, Eunchong Park, Patrick A. Dome, Michael J. Hoy, Ivan Spasojevic, Sheng Sun, Anna Floyd Averette, Sergio Pina-Oviedo, Praveen R. Juvvadi, William J. Steinbach, Maria Ciofani, Jiyong Hong, Joseph Heitman
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Fungal infections are of mounting global concern, and the current limited treatment arsenal poses challenges when treating such infections. In particular, infections by Cryptococcus neoformans are associated with high mortality, emphasizing
Externí odkaz:
https://doaj.org/article/ce0b324bccb346759ee1b133f5211833
Autor:
Michael J. Hoy, Eunchong Park, Hyunji Lee, Won Young Lim, D. Christopher Cole, Nicholas D. DeBouver, Benjamin G. Bobay, Phillip G. Pierce, David Fox, Maria Ciofani, Praveen R. Juvvadi, William Steinbach, Jiyong Hong, Joseph Heitman
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Calcineurin is an essential virulence factor that is conserved across human fungal pathogens, including Cryptococcus neoformans, Aspergillus fumigatus, and Candida albicans. Although an excellent target for antifungal drug development, the s
Externí odkaz:
https://doaj.org/article/117f01418524456e8457bbd3d23cdecf
Autor:
Gregory Swan, Jia Geng, Eunchong Park, Quanquan Ding, John Zhou, Ciana Walcott, Junyi J. Zhang, Hsin-I. Huang, Gianna Hammer, Donghai Wang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/63c5e741ca184f288493a9c234bbd1f8
Autor:
Gregory Swan, Jia Geng, Eunchong Park, Quanquan Ding, John Zhou, Ciana Walcott, Junyi J. Zhang, Hsin-I Huang, Gianna Elena Hammer, Donghai Wang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Precisely controlled lymphocyte migration is critically required for immune surveillance and successful immune responses. Lymphocyte migration is strictly regulated by chemokines and chemokine receptors. Here we show that protein geranylgeranylation,
Externí odkaz:
https://doaj.org/article/1a6ba6bd98644d0d8c2cfc80690dd3da
Publikováno v:
Korean Journal of Human Ecology. 31:275-288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::305132ae73b2706b05e3ec4a00ea4c68
https://doi.org/10.5934/kjhe.2022.31.2.275
https://doi.org/10.5934/kjhe.2022.31.2.275
Autor:
Michael J. Hoy, Eunchong Park, Hyunji Lee, Won Young Lim, D. Christopher Cole, Nicholas D. DeBouver, Benjamin G. Bobay, Phillip G. Pierce, David Fox, Maria Ciofani, Praveen R. Juvvadi, William Steinbach, Jiyong Hong, Joseph Heitman
Publikováno v:
mBio. 13
Due to rising rates of antifungal drug resistance and a limited armamentarium of antifungal treatments, there is a paramount need for novel antifungal drugs to treat systemic fungal infections. Calcineurin has been established as an essential and con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89d5e3691f424b12df939e277bf0aabc
https://doi.org/10.1128/mbio.01049-22
https://doi.org/10.1128/mbio.01049-22
Publikováno v:
The transactions of The Korean Institute of Electrical Engineers. 68:1694-1703
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04b973af35d56c6339235de4e063399b
https://doi.org/10.5370/kiee.2019.68.12.1694
https://doi.org/10.5370/kiee.2019.68.12.1694
Autor:
Tae Sung Kim, Jaekyoon Shin, Hyun Kyu Song, Eunju Kim, In Young Lee, Yeojin Lee, Dae-Sik Lim, Eui Ju Choi, Danbi Lee, Je-Hyun Yoon, Eunchong Park, Kyung Hye Roh
Publikováno v:
Cellular and molecular life sciences : CMLS. 78(5)
Pattern-recognition receptors including Toll-like receptors (TLRs) recognize invading pathogens and trigger an immune response in mammals. Here we show that mammalian ste20-like kinase 1/serine/threonine kinase 4 (MST1/STK4) functions as a negative r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346799a7012fa6075ba21e13d3c4ad69
https://pubmed.ncbi.nlm.nih.gov/32975614
https://pubmed.ncbi.nlm.nih.gov/32975614
Publikováno v:
Biochemical and Biophysical Research Communications. 489:56-62
MST1 deficiency causes T and B cell lymphopenia, resulting in combined immunodeficiency. However, MST1-deficient patients also exhibit autoimmune-like symptoms such as hypergammaglobulinemia and autoantibody production. Recent studies have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94748dda06466bc1203eae7b4b03fe10
https://doi.org/10.1016/j.bbrc.2017.05.094
https://doi.org/10.1016/j.bbrc.2017.05.094
Publikováno v:
International Immunopharmacology. 40:508-516
CD4+ T cell activation and adequate differentiation into effector T helper (Th) cells are crucial for mediating adaptive immune responses to cope with foreign pathogens. Despite the significant role of Th cells, excessive increases in their numbers r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3b98a12f8dcabff0e3616fdc202df58
https://doi.org/10.1016/j.intimp.2016.10.006
https://doi.org/10.1016/j.intimp.2016.10.006