Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Eunchai Kang"'
Publikováno v:
Communicative & Integrative Biology, Vol 11, Iss 2, Pp 1-4 (2018)
Experiments conducted in non-human primates have recently provided new evidence supporting a longstanding concern that exposure to general anesthesia during late intrauterine life or early childhood can cause lasting cognitive deficits through harmfu
Externí odkaz:
https://doaj.org/article/3224c11312c843409b2775041fb20bdb
Autor:
Hongsheng Zhang, Eunchai Kang, Yaqing Wang, Chaojuan Yang, Hui Yu, Qin Wang, Zheyu Chen, Chen Zhang, Kimberly M. Christian, Hongjun Song, Guo-li Ming, Zhiheng Xu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The in vivo function of CRMP2 is unclear. Zhang et al. generate and characterize brain-specific Crmp2knockout mice. These mice show impairments in hippocampal neurogenesis, neuronal maturation and synaptic transmission, and exhibit schizophrenia-rela
Externí odkaz:
https://doaj.org/article/606608a70bca406f8d586bffd848128c
Autor:
Eunchai Kang, Danye Jiang, Yun Kyoung Ryu, Sanghee Lim, Minhye Kwak, Christy D Gray, Michael Xu, Jun H Choi, Sue Junn, Jieun Kim, Jing Xu, Michele Schaefer, Roger A Johns, Hongjun Song, Guo-Li Ming, C David Mintz
Publikováno v:
PLoS Biology, Vol 15, Iss 7, p e2001246 (2017)
Clinical and preclinical studies indicate that early postnatal exposure to anesthetics can lead to lasting deficits in learning and other cognitive processes. The mechanism underlying this phenomenon has not been clarified and there is no treatment c
Externí odkaz:
https://doaj.org/article/5d764841eacc4757a5a6daeaa9528be3
Autor:
Hongsheng Zhang, Eunchai Kang, Yaqing Wang, Chaojuan Yang, Hui Yu, Qin Wang, Zheyu Chen, Chen Zhang, Kimberly M. Christian, Hongjun Song, Guo-li Ming, Zhiheng Xu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 7: Article number: 11773 (2016); Published 1 June 2016, Updated 18 July 2018 The original HTML version of this Article had an incorrect article number of ‘0’; it should have been ‘11773’. This has now been corrected in t
Externí odkaz:
https://doaj.org/article/ad5be1823bd64af1a5db6f14722b290c
Autor:
Viola Neudecker, Jing Xu, Monica A. Thomas, Kristen K. Penberthy, Eunchai Kang, Daniel A. Berg, Alia M.I. O’Meara, Ansgar M. Brambrink, Cyrus David Mintz
Publikováno v:
Journal of Neurosurgical Anesthesiology. 35:104-113
Publikováno v:
Expert Reviews in Molecular Medicine. 25
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterised by gradual memory loss and declining cognitive and executive functions. AD is the most common cause of dementia, affecting more than 50 million people worldwide, and i
Autor:
Yaqing Wang, Hongjun Song, Chen Zhang, Guo Li Ming, Hongsheng Zhang, Chaojuan Yang, Qin Wang, Kimberly M. Christian, Eunchai Kang, Zhiheng Xu, Hui Yu, Zheyu Chen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
Several genome- and proteome-wide studies have associated transcription and translation changes of CRMP2 (collapsing response mediator protein 2) with psychiatric disorders, yet little is known about its function in the developing or adult mammalian
Autor:
Eunchai Kang, Guo Li Ming, Jieun Kim, Mao Mao, Cong Yu, Xuyu Qian, Mingjie Zhang, Fadi Jacob, Fei Ye, Chuan Yu, Hongjun Song, Randy Yat Choi Poon
Summary Mutations of DISC1 (disrupted-in-schizophrenia 1) have been associated with major psychiatric disorders. Despite the hundreds of DISC1-binding proteins reported, almost nothing is known about how DISC1 interacts with other proteins structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1064c21a208d8fb27eb1e0f56147da
https://europepmc.org/articles/PMC5902170/
https://europepmc.org/articles/PMC5902170/
Autor:
Hongjun Song, Yun Kyoung Ryu, Minhye Kwak, Sanghee Lim, C. David Mintz, Eunchai Kang, Orion Furmanski
Publikováno v:
Developmental Neuroscience. 37:428-439
Neonatal hypoxic-ischemic injury (HI) results in widespread cerebral encephalopathy and affects structures that are essential for neurocognitive function, such as the hippocampus. The dentate gyrus contains a reservoir of neural stem and progenitor c
Autor:
Benedikt Berninger, Guo Li Ming, Jennifer H. Lee, Jaesuk Park, Qassim Hussani, Shaoyu Ge, Yu-Ting Lin, Hongjun Song, Kuei Sen Hsu, Weidong Li, Juan Song, Yan Gu, Kimberly M. Christian, Eunchai Kang
Publikováno v:
Cell Reports. 28:1419-1428.e3
Excitation-inhibition (E-I) imbalance is considered a hallmark of various neurodevelopmental disorders, including schizophrenia and autism. How genetic risk factors disrupt coordinated glutamatergic and GABAergic synapse formation to cause an E-I imb