Zobrazeno 1 - 10
of 154
pro vyhledávání: '"EunYoung Choi"'
Autor:
Jaeseung Song, Daeun Kim, Junghyun Jung, Eunyoung Choi, Yubin Lee, Yeonbin Jeong, Byungjo Lee, Sora Lee, Yujeong Shim, Youngtae Won, Hyeki Cho, Dong Kee Jang, Hyoun Woo Kang, Jong Wha J. Joo, Wonhee Jang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Colorectal cancer (CRC) is one of the top five most common and life-threatening malignancies worldwide. Most CRC develops from advanced colorectal adenoma (ACA), a precancerous stage, through the adenoma-carcinoma sequence. However, its unde
Externí odkaz:
https://doaj.org/article/27d64cc284da4f30a0856a4aae197197
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-15 (2024)
Abstract Background Male-pattern baldness (MPB) is the most common cause of hair loss in men. It can be categorized into three types: type 2 (T2), type 3 (T3), and type 4 (T4), with type 1 (T1) being considered normal. Although various MPB-associated
Externí odkaz:
https://doaj.org/article/d53c906b15c44335a0e6cfb284ada755
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 671-678 (2024)
Numerous recent studies using single cell RNA sequencing and spatial transcriptomics have shown the vast cell heterogeneity, including epithelial, immune, and stromal cells, present in the normal human stomach and at different stages of gastric carci
Externí odkaz:
https://doaj.org/article/947d05aa076f4c58b9466f5d15e7bbcd
Autor:
Ela W. Contreras-Panta, Su-Hyung Lee, Yoonkyung Won, Allison E. Norlander, Alan J. Simmons, R. Stokes Peebles, Jr., Ken S. Lau, Eunyoung Choi, James R. Goldenring
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 3, Pp 101366- (2024)
Background & Aims: Type 2 innate lymphoid cells (ILC2s) and interleukin-13 (IL-13) promote the onset of spasmolytic polypeptide-expressing metaplasia (SPEM) cells. However, little is known about molecular effects of IL-13 in SPEM cells. We now sought
Externí odkaz:
https://doaj.org/article/3f940af3bdcd40e5b822af7b7b0a90b6
Autor:
Yoojin Sohn, Blake Flores Semyonov, Hilana El-Mekkoussi, Christopher V.E. Wright, Klaus H. Kaestner, Eunyoung Choi, James R. Goldenring
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 2, Pp 101347- (2024)
Background & Aim: Telocytes, a recently identified type of subepithelial interstitial cell, have garnered attention for their potential roles in tissue homeostasis and repair. However, their contribution to gastric metaplasia remains unexplored. This
Externí odkaz:
https://doaj.org/article/7b0dd0e94c0442778503ccb239bcf01f
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0300745 (2024)
ObjectiveThis study aimed to investigate the impacts of continuity of care (COC) between patients and multiple providers, i.e., doctors and community pharmacists, on clinical and economic outcomes.MethodsThis is a retrospective cohort study and analy
Externí odkaz:
https://doaj.org/article/67c0032fcd254e2ab66562a1dd6f596f
Autor:
Bogun Jang, Hyesung Kim, Su‐Hyung Lee, Yoonkyung Won, Izumi Kaji, Robert J Coffey, Eunyoung Choi, James R Goldenring
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract Tuft cells are chemosensory cells associated with luminal homeostasis, immune response, and tumorigenesis in the gastrointestinal tract. We aimed to elucidate alterations in tuft cell populations during gastric atrophy and tumorigenesis in h
Externí odkaz:
https://doaj.org/article/a2ba229ff5854ec7a9ed6d4404be232c
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 131-142 (2022)
RNA-guided CRISPR-Cas12a endonucleases are promising tools for genome engineering. Here we demonstrate that LbCas12a variants derived from Lachnospiraceae bacterium show a broad PAM preference, recognizing certain non-canonical PAMs with high efficie
Externí odkaz:
https://doaj.org/article/28487c51b2054be69abf5d9e4a62a820
Autor:
Deronisha Arceneaux, Zhengyi Chen, Alan J. Simmons, Cody N. Heiser, Austin N. Southard-Smith, Michael J. Brenan, Yilin Yang, Bob Chen, Yanwen Xu, Eunyoung Choi, Joshua D. Campbell, Qi Liu, Ken S. Lau
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107242- (2023)
Summary: Droplet-based single-cell RNA-seq (scRNA-seq) data are plagued by ambient contaminations caused by nucleic acid material released by dead and dying cells. This material is mixed into the buffer and is co-encapsulated with cells, leading to a
Externí odkaz:
https://doaj.org/article/023e2b611ee743e9a29a87c90b558a38
Publikováno v:
EClinicalMedicine, Vol 58, Iss , Pp 101911- (2023)
Summary: Background: Socioeconomic inequality in access to and use of health services and social care provided near the end of life, or end-of-life care (EOLC), is not well understood in many countries. We examined wealth inequality in EOLC—hospita
Externí odkaz:
https://doaj.org/article/fd4819f8cdd0423e93c359fb3a6132db