Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Eun Young Shin"'
Publikováno v:
Journal of Pharmaceutical Policy and Practice, Vol 17, Iss 1 (2024)
Introduction: In this study, we aimed to comparatively analyse the indicators of availability to orphan drugs in South Korea, the United States of America, Europe Union, and Japan.Methods: For 169 drugs designated as orphan drugs in South Korea betwe
Externí odkaz:
https://doaj.org/article/de3377690b5e410cb69b0cc9610064ee
Publikováno v:
International Journal of Ophthalmology, Vol 10, Iss 11, Pp 1647-1654 (2017)
AIM: To investigate the anti-(lymph)angiogenic and/or anti-inflammatory effect of itraconazole in a corneal suture model and penetrating keratoplasty (PK) model. METHODS: Graft survival, corneal neovascularization, and corneal lymphangiogenesis were
Externí odkaz:
https://doaj.org/article/f89405b8704d43729e95a18ae50e0ed8
Publikováno v:
International Journal of Ophthalmology, Vol 10, Iss 6, Pp 834-839 (2017)
AIM: To evaluate the effect of sorafenib in murine high risk keratoplasty model. METHODS: Graft survival, corneal neovascularization, and corneal lymphangiogenesis were compared among the sorafenib, dexamethasone, dimethyl sulfoxide (DMSO), and phos
Externí odkaz:
https://doaj.org/article/d7a5bb582aae4ed2982224c050ea4692
Autor:
Jin Woo Kwon, Jin A Choi, Eun Young Shin, Tae Yoon La, Dong Hyun Jee, Yeon Woong Chung, Yang Kyung Cho
Publikováno v:
International Journal of Ophthalmology, Vol 9, Iss 11, Pp 1541-1548 (2016)
AIM: To evaluate whether trapping vascular endothelial growth factor A (VEGF-A) would suppress angiogenesis and inflammation in dry eye corneas in a murine corneal suture model. METHODS: We established two groups of animals, one with non-dry eyes an
Externí odkaz:
https://doaj.org/article/9d3d35092b1c4450b71a736297fb56b1
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Sertoli cells (SCs) in the mammalian testes are well known as supporting cells of spermatogenesis, but have recently become an attractive source of cell therapy because of their capacity for immune modulation and trophic effects. In order to increase
Externí odkaz:
https://doaj.org/article/5c15fef20ad644a68092be9f4e84d40c
Autor:
Jung-Jin Park, Kwangseok Oh, Gun-Wu Lee, Geul Bang, Jin-Hee Park, Han-Byeol Kim, Jin Young Kim, Eun-Young Shin, Eung-Gook Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 4, Pp 794-805 (2023)
Abstract Senescence, a hallmark of aging, is a factor in age-related diseases (ARDs). Therefore, targeting senescence is widely regarded as a practicable method for modulating the effects of aging and ARDs. Here, we report the identification of regor
Externí odkaz:
https://doaj.org/article/596467903462476eabef0d4df5a126ae
Autor:
So-Yoon Won, Jung-Jin Park, Soon-Tae You, Jong-A Hyeun, Hyong-Kyu Kim, Byung Kwan Jin, Catriona McLean, Eun-Young Shin, Eung-Gook Kim
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-13 (2022)
Abstract Aggregation of misfolded alpha-synuclein (α-synuclein) is a central player in the pathogenesis of neurodegenerative diseases. Therefore, the regulatory mechanism underlying α-synuclein aggregation has been intensively studied in Parkinson
Externí odkaz:
https://doaj.org/article/ea5257c7141342b589cea8d0d933be1d
Autor:
Ho Won Kang, Xuan-Mei Piao, Hee Youn Lee, Kyeong Kim, Sung Pil Seo, Yun-Sok Ha, Yeong Uk Kim, Won Tae Kim, Yong-June Kim, Sang-Cheol Lee, Wun-Jae Kim, Eun-Young Shin, Eung-Gook Kim, Seok Joong Yun
Publikováno v:
Investigative and Clinical Urology, Vol 62, Iss 4, Pp 399-407 (2021)
Purpose: P21-activated kinase 4 (PAK4), a serine/threonine kinase that regulates a number of fundamental cellular processes, has been suggested as a prognostic factor for various human tumors. The aim of the present study was to evaluate the clinical
Externí odkaz:
https://doaj.org/article/db26c594e7e4403ca5664ddc2674a56a
Autor:
Eun-Young Shin, Da-Seul Kim, Min Ji Lee, Ah Reum Lee, Sung Han Shim, Seung Woon Baek, Dong Keun Han, Dong Ryul Lee
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-20 (2021)
Abstract Background Premature ovarian insufficiency (POI) is one of the most serious side effects of chemotherapy in young cancer survivors. It may not only reduce fecundity but also affect lifelong health. There is no standard therapy for preserving
Externí odkaz:
https://doaj.org/article/31f3742fd58e4e528fcbaaa63d14deb3
Autor:
Fotis Tsetsos, Dongmei Yu, Jae Hoon Sul, Alden Y. Huang, Cornelia Illmann, Lisa Osiecki, Sabrina M. Darrow, Matthew E. Hirschtritt, Erica Greenberg, Kirsten R. Muller-Vahl, Manfred Stuhrmann, Yves Dion, Guy A. Rouleau, Harald Aschauer, Mara Stamenkovic, Monika Schlögelhofer, Paul Sandor, Cathy L. Barr, Marco A. Grados, Harvey S. Singer, Markus M. Nöthen, Johannes Hebebrand, Anke Hinney, Robert A. King, Thomas V. Fernandez, Csaba Barta, Zsanett Tarnok, Peter Nagy, Christel Depienne, Yulia Worbe, Andreas Hartmann, Cathy L. Budman, Renata Rizzo, Gholson J. Lyon, William M. McMahon, James R. Batterson, Danielle C. Cath, Irene A. Malaty, Michael S. Okun, Cheston Berlin, Douglas W. Woods, Paul C. Lee, Joseph Jankovic, Mary M. Robertson, Donald L. Gilbert, Lawrence W. Brown, Barbara J. Coffey, Andrea Dietrich, Pieter J. Hoekstra, Samuel Kuperman, Samuel H. Zinner, Michael Wagner, James A. Knowles, A. Jeremy Willsey, Jay A. Tischfield, Gary A. Heiman, Nancy J. Cox, Nelson B. Freimer, Benjamin M. Neale, Lea K. Davis, Giovanni Coppola, Carol A. Mathews, Jeremiah M. Scharf, Peristera Paschou, on behalf of the Tourette Association of America International Consortium for Genetics, Sabrina Darrow, Roger Kurlan, James F. Leckman, Jan H. Smit, the Gilles de la Tourette GWAS Replication Initiative, Harald Aschauer Harald Aschauer, Anastasios Konstantinidis, Kirsten Müller-Vahl, Tomasz Wolanczyk, the Tourette International Collaborative Genetics Study, Lawrence Brown, Keun-Ah Cheon, Blanca Garcia-Delgar, Donald Gilbert, Dorothy E. Grice, Julie Hagstrøm, Tammy Hedderly, Isobel Heyman, Chaim Huyser, Young Key Kim, Young-Shin Kim, Yun-Joo Koh, Sodahm Kook, Bennett L. Leventhal, Marcos Madruga-Garrido, Pablo Mir, Astrid Morer, Alexander Münchau, Kerstin J. Plessen, Veit Roessner, Eun-Young Shin, Dong-Ho Song, Jungeun Song, Samuel Zinner, and the Psychiatric Genomics Consortium Tourette Syndrome Working Group, Thomas Fernandez, Gary Heiman, Pieter Hoekstra, Jay Tischfield, Douglas Woods
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie the neurobiology of the disorder through genome-wide analysis
Externí odkaz:
https://doaj.org/article/1e03ee514141459ab171b2316307b113