Zobrazeno 1 - 10
of 4 629
pro vyhledávání: '"Eun Sung"'
Autor:
Jianliang Xu, Tongqing Zhou, Krisha McKee, Baoshan Zhang, Cuiping Liu, Alexandra F. Nazzari, Amarendra Pegu, Chen‐Hsiang Shen, Jordan E. Becker, Michael F. Bender, Payton Chan, Anita Changela, Ridhi Chaudhary, Xuejun Chen, Tal Einav, Young Do Kwon, Bob C. Lin, Mark K. Louder, Jonah S. Merriam, Nicholas C. Morano, Sijy O'Dell, Adam S. Olia, Reda Rawi, Ryan S. Roark, Tyler Stephens, I‐Ting Teng, Emily Tourtellott‐Fogt, Shuishu Wang, Eun Sung Yang, Lawrence Shapiro, Yaroslav Tsybovsky, Nicole A. Doria‐Rose, Rafael Casellas, Peter D. Kwong
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Broadly neutralizing antibodies are proposed as therapeutic and prophylactic agents against HIV‐1, but their potency and breadth are less than optimal. This study describes the immunization of a llama with the prefusion‐stabilized HIV‐
Externí odkaz:
https://doaj.org/article/2af27b428ce0453586e0f60b99fd2446
Autor:
Hyekyung Yang, Dong Ho Suh, Eun Sung Jung, Yoonjin Lee, Kwang-Hyeon Liu, In-Gu Do, Choong Hwan Lee, Cheol-Young Park
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundEzetimibe, which lowers cholesterol by blocking the intestinal cholesterol transporter Niemann-Pick C1 like 1, is reported to reduce hepatic steatosis in humans and animals. Here, we demonstrate the changes in hepatic metabolites and lipids
Externí odkaz:
https://doaj.org/article/bcff0589bbb74f7c85b4b09df7c91925
Autor:
Ye Ji Kim, Zinah Hilal Khaleel, Myeongji Jin, Jo Woon Yi Lee, Seongchan Park, Seongmin Ga, Nam Hyeong Kim, Deok Hyang Sa, Eun Sung Kang, Seul Hee Han, Ji Yeun Lee, Hyo Jung Ku, Sang-Wook Kim, Ki Yong Kim, Jeong Euy Park, Yong Ho Kim, Bok-Soo Lee
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract High-density lipoprotein (HDL) therapy has demonstrated beneficial effects in acute stroke and acute myocardial infarction models by reducing infarct size. In this study, we investigated the inhibitory effects of reconstituted HDL (rHDL) on
Externí odkaz:
https://doaj.org/article/6fb0e83fab8845be809ea143587e0f00
Publikováno v:
Biosensors, Vol 14, Iss 10, p 454 (2024)
Mercury ions (Hg2+) are toxic heavy metals present in the environment that pose significant health risks. An advanced detection system could allow for a prompt response and alleviate serious damage to humans. In this study, we developed a cost-effect
Externí odkaz:
https://doaj.org/article/95a096ef09db42dcb5206497d0c59ea4
Autor:
Chae-Lin Park, Byeonghwa Goh, Keon Jung Kim, Seongjae Oh, Dongseok Suh, Young-Chul Song, Hyun Kim, Eun Sung Kim, Habeom Lee, Dong Wook Lee, Joonmyung Choi, Shi Hyeong Kim
Publikováno v:
Materials Today Advances, Vol 21, Iss , Pp 100459- (2024)
Electrochemically powered carbon nanotube (CNT) yarn muscles are of increasing interest because of their advantageous features as artificial muscles. They are light, and have high electrical properties, mechanical strength, and chemical stability. Tw
Externí odkaz:
https://doaj.org/article/ff82f41266e84db8abefb39fc1aecc79
Publikováno v:
Foods, Vol 13, Iss 14, p 2227 (2024)
The beneficial effects of probiotics for the improvement of metabolic disorders have been studied intensively; however, these effects are evident in a probiotic strain-specific and disease-specific manner. Thus, it is still essential to evaluate the
Externí odkaz:
https://doaj.org/article/c675a1920bbc46ed995bb15545bfd9a4
Autor:
Cuiping Liu, Lingshu Wang, Jonah S. Merriam, Wei Shi, Eun Sung Yang, Yi Zhang, Man Chen, Wing-Pui Kong, Cheng Cheng, Yaroslav Tsybovsky, Tyler Stephens, Raffaello Verardi, Kwanyee Leung, Cody Stein, Adam S. Olia, Darcy R. Harris, Misook Choe, Baoshan Zhang, Barney S. Graham, Peter D. Kwong, Richard A. Koup, Amarendra Pegu, John R. Mascola
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract While several COVID-19 vaccines have been in use, more effective and durable vaccines are needed to combat the ongoing COVID-19 pandemic. Here, we report highly immunogenic self-assembling SARS-CoV-2 spike-HBsAg nanoparticles displaying a si
Externí odkaz:
https://doaj.org/article/9b37253d44914adeb9ec845f4062bcd4
Autor:
Boyeon Kim, Jiwon Lee, Eun Sung Jung, Sunyoung Lee, Dong Ho Suh, Yu Jin Park, Jin Kim, Jung-Myun Kwak, Soohyeon Lee
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
A high-fiber diet is widely recognized for its positive effects on the gut microbiome. However, the specific impact of a high-fiber diet on the gut microbiome and bowel habits of patients with colon cancer remains poorly understood. In this study, we
Externí odkaz:
https://doaj.org/article/a5078cde82824ea8898afa95e8803dbe
Autor:
Young D. Kwon, Amarendra Pegu, Eun Sung Yang, Baoshan Zhang, Michael F. Bender, Mangaiarkarasi Asokan, Qingbo Liu, Krisha McKee, Bob C. Lin, Tracy Liu, Mark K. Louder, Reda Rawi, Mateo Reveiz, Andrew J. Schaub, Chen-Hsiang Shen, Nicole A. Doria-Rose, Paolo Lusso, John R. Mascola, Peter D. Kwong
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTThe amino-acid composition of the immunoglobulin variable region has been observed to impact antibody pharmacokinetics (PK). Here, we sought to improve the PK of the broad HIV−1-neutralizing VRC01-class antibodies, VRC07-523LS and N6LS, by
Externí odkaz:
https://doaj.org/article/404c6bcba63e47658183c99f62376df3
Autor:
Baoshan Zhang, Jason Gorman, Young D. Kwon, Amarendra Pegu, Cara W. Chao, Tracy Liu, Mangaiarkarasi Asokan, Michael F. Bender, Tatsiana Bylund, Leland Damron, Deepika Gollapudi, Paula Lei, Yile Li, Cuiping Liu, Mark K. Louder, Krisha McKee, Adam S. Olia, Reda Rawi, Arne Schön, Shuishu Wang, Eun Sung Yang, Yongping Yang, Kevin Carlton, Nicole A. Doria-Rose, Lawrence Shapiro, Michael S. Seaman, John R. Mascola, Peter D. Kwong
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAntibody CAP256-VRC26.25 targets the second hypervariable region (V2) at the apex of the HIV envelope (Env) trimer with extraordinary neutralization potency, although less than optimal breadth. To improve breadth, we linked the light chain of
Externí odkaz:
https://doaj.org/article/bddbe9ec6f5b4b779bcbe4b49830cab8